A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP
about
Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugatesEfficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motifStabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor proteinNovel Src homology 3 domain-binding motifs identified from proteomic screen of a Pro-rich regionBalanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/WntInteraction of nebulin SH3 domain with titin PEVK and myopalladin: implications for the signaling and assembly role of titin and nebulinMutations in STAMBP, encoding a deubiquitinating enzyme, cause microcephaly-capillary malformation syndromeThe MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradationLoss of neurons in the hippocampus and cerebral cortex of AMSH-deficient mice.The deubiquitinating enzyme USP8 promotes trafficking and degradation of the chemokine receptor 4 at the sorting endosomeThe ESCRT complexesThe FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and beta-cateninRegulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complexRegulation and cellular roles of ubiquitin-specific deubiquitinating enzymesSTAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motifAMSH is an endosome-associated ubiquitin isopeptidaseRelease of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 buddingThe ESCRT complexes: structure and mechanism of a membrane-trafficking networkThe business of deubiquitination - location, location, locationThe ESCRT machinery: from the plasma membrane to endosomes and back againUnusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysisDiverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p.Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domainThe Vps27/Hse1 Complex Is a GAT Domain-Based Scaffold for Ubiquitin-Dependent SortingUbiquitin binds to and regulates a subset of SH3 domainsProtein-protein interactions of ESCRT complexes in the yeast Saccharomyces cerevisiae.The deubiquitinating enzyme Ubp1 affects sorting of the ATP-binding cassette-transporter Ste6 in the endocytic pathway.Ras-GAP SH3 domain binding protein (G3BP) is a modulator of USP10, a novel human ubiquitin specific proteaseUCS15A, a novel small molecule, SH3 domain-mediated protein-protein interaction blocking drugStimulation of hTAFII68 (NTD)-mediated transactivation by v-SrcAmino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8)Phosphoproteomic analysis of the developing mouse brainRegulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomesFunctional and structural characterization of a novel putative cysteine protease cell wall-modifying multi-domain enzyme selected from a microbial metagenome.A graph kernel approach for alignment-free domain-peptide interaction prediction with an application to human SH3 domainsCompetitive binding of UBPY and ubiquitin to the STAM2 SH3 domain revealed by NMR.Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling.Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction
P2860
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P2860
A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
A deubiquitinating enzyme UBPY ...... inding motif PX(V/I)(D/N)RXXKP
@ast
A deubiquitinating enzyme UBPY ...... inding motif PX(V/I)(D/N)RXXKP
@en
A deubiquitinating enzyme UBPY ...... inding motif PX(V/I)(D/N)RXXKP
@nl
type
label
A deubiquitinating enzyme UBPY ...... inding motif PX(V/I)(D/N)RXXKP
@ast
A deubiquitinating enzyme UBPY ...... inding motif PX(V/I)(D/N)RXXKP
@en
A deubiquitinating enzyme UBPY ...... inding motif PX(V/I)(D/N)RXXKP
@nl
prefLabel
A deubiquitinating enzyme UBPY ...... inding motif PX(V/I)(D/N)RXXKP
@ast
A deubiquitinating enzyme UBPY ...... inding motif PX(V/I)(D/N)RXXKP
@en
A deubiquitinating enzyme UBPY ...... inding motif PX(V/I)(D/N)RXXKP
@nl
P2860
P921
P356
P1476
A deubiquitinating enzyme UBPY ...... inding motif PX(V/I)(D/N)RXXKP
@en
P2093
P2860
P304
37481-37487
P356
10.1074/JBC.M007251200
P407
P50
P577
2000-12-01T00:00:00Z