Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76
about
Efficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motifRegulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor proteinThe X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activationNovel Src homology 3 domain-binding motifs identified from proteomic screen of a Pro-rich regionExpression, refolding and crystallizations of the Grb2-like (GADS) C-terminal SH3 domain complexed with a SLP-76 motif peptideRecognition of tandem PxxP motifs as a unique Src homology 3-binding mode triggers pathogen-driven actin assemblySH3 domains of Grb2 adaptor bind to PXpsiPXR motifs within the Sos1 nucleotide exchange factor in a discriminate mannerA unique set of SH3-SH3 interactions controls IB1 homodimerization.Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complexAMSH interacts with ESCRT-0 to regulate the stability and trafficking of CXCR4Structure of the fungal beta-glucan-binding immune receptor dectin-1: implications for functionCD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76SH3 domain ligand binding: What's the consensus and where's the specificity?Membrane curvature and its generation by BAR proteinsEnterohaemorrhagic Escherichia Coli Exploits a Tryptophan Switch to Hijack Host F-Actin AssemblyThe promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A proteinOrder and disorder in large multi-site docking proteins of the Gab family--implications for signalling complex formation and inhibitor design strategiesFunctional cross-talk between ras and rho pathways: a Ras-specific GTPase-activating protein (p120RasGAP) competitively inhibits the RhoGAP activity of deleted in liver cancer (DLC) tumor suppressor by masking the catalytic arginine fingerMona/Gads SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helixThe Huntington's disease mutation impairs Huntingtin's role in the transport of NF-κB from the synapse to the nucleus.Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hubEvolution of domain-peptide interactions to coadapt specificity and affinity to functional diversitySH3 domains: modules of protein-protein interactions.Grb2 carboxyl-terminal SH3 domain can bivalently associate with two ligands, in an SH3 dependent manner.Exhaustive search of linear information encoding protein-peptide recognitionIntracellular mechanisms of molecular recognition and sorting for transport of large extracellular matrix moleculesLarge-Scale Screening of Preferred Interactions of Human Src Homology-3 (SH3) Domains Using Native Target Proteins as Affinity LigandsThe Binding of Syndapin SH3 Domain to Dynamin Proline-rich Domain Involves Short and Long Distance ElementsThe proline-rich region of 18.5 kDa myelin basic protein binds to the SH3-domain of Fyn tyrosine kinase with the aid of an upstream segment to form a dynamic complex in vitro.Novel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screenCommentary: The carboxyl-terminal Crk SH3 domain: Regulatory strategies and new perspectives.Importance of CH/π hydrogen bonds in recognition of the core motif in proline-recognition domains: an ab initio fragment molecular orbital study.Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transductionThe neuronal proteins CIPP, Cypin and IRSp53 form a tripartite complex mediated by PDZ and SH3 domains.Role of the Kaposi's sarcoma-associated herpesvirus K15 SH3 binding site in inflammatory signaling and B-cell activation.Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain.Intracellular protein interaction mapping with FRET hybrids.Regulation of RhoGEF activity by intramolecular and intermolecular SH3 domain interactions.Transactivation of Abl by the Crk II adapter protein requires a PNAY sequence in the Crk C-terminal SH3 domain.Structural basis for recognition of the T cell adaptor protein SLP-76 by the SH3 domain of phospholipase Cgamma1
P2860
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P2860
Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Structural basis for SH3 domai ...... g between Mona/Gads and SLP-76
@ast
Structural basis for SH3 domai ...... g between Mona/Gads and SLP-76
@en
Structural basis for SH3 domai ...... g between Mona/Gads and SLP-76
@nl
type
label
Structural basis for SH3 domai ...... g between Mona/Gads and SLP-76
@ast
Structural basis for SH3 domai ...... g between Mona/Gads and SLP-76
@en
Structural basis for SH3 domai ...... g between Mona/Gads and SLP-76
@nl
prefLabel
Structural basis for SH3 domai ...... g between Mona/Gads and SLP-76
@ast
Structural basis for SH3 domai ...... g between Mona/Gads and SLP-76
@en
Structural basis for SH3 domai ...... g between Mona/Gads and SLP-76
@nl
P2093
P2860
P356
P1433
P1476
Structural basis for SH3 domai ...... g between Mona/Gads and SLP-76
@en
P2093
Guy Mouchiroud
Holger Sondermann
Ismail Moarefi
Marc Lewitzky
Maria Harkiolaki
Roland P Bourette
Stephan M Feller
P2860
P304
P356
10.1093/EMBOJ/CDG258
P407
P577
2003-06-01T00:00:00Z