Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange
about
Cellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegenerationAstrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegenerationCentral Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic BrainLong-range and short-range tumor-stroma networks synergistically contribute to tumor-associated epilepsy.Perspectives in Intraoperative Diagnostics of Human GliomasEpilepsy related to developmental tumors and malformations of cortical developmentThinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signalingSLC7A11 expression is associated with seizures and predicts poor survival in patients with malignant gliomaGABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy.High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma CellsAttenuated AMPA receptor expression allows glioblastoma cell survival in glutamate-rich environmentMetabotropic glutamate receptors as a new therapeutic target for malignant gliomasRole of glutamate transporters in redox homeostasis of the brain.Phase 2 trial of talampanel, a glutamate receptor inhibitor, for adults with recurrent malignant gliomas.Glutamate as a neurotransmitter in the healthy brainSystem x(c)(-) regulates microglia and macrophage glutamate excitotoxicity in vivoGlioblastoma development in mouse brain: general reduction of OCTs and mislocalization of OCT3 transporter and subsequent uptake of ASP(+) substrate to the nucleiSystem xc⁻ cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS.Isoxazole analogues bind the system xc- transporter: structure-activity relationship and pharmacophore model.The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.Hypoxia increases the dependence of glioma cells on glutathioneA role for ion channels in glioma cell invasionOverexpression of calcium-permeable glutamate receptors in glioblastoma derived brain tumor initiating cells.Sulfasalazine inhibits the growth of primary brain tumors independent of nuclear factor-kappaB.Functional changes in glutamate transporters and astrocyte biophysical properties in a rodent model of focal cortical dysplasiaSynergistic inhibition of survival, proliferation, and migration of U87 cells with a combination of LY341495 and Iressa.Augmented cystine-glutamate exchange by pituitary adenylate cyclase-activating polypeptide signaling via the VPAC1 receptor.Efficacy of local polymer-based and systemic delivery of the anti-glutamatergic agents riluzole and memantine in rat glioma models.Glutamate release by primary brain tumors induces epileptic activityOncogene AEG-1 promotes glioma-induced neurodegeneration by increasing glutamate excitotoxicity.The role of metabolic therapy in treating glioblastoma multiforme.Cortical GABAergic excitation contributes to epileptic activities around human glioma.The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells.Regulation of system x(c)(-)activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injuryIon channels and amino acid transporters support the growth and invasion of primary brain tumors.Non-cell autonomous influence of the astrocyte system xc- on hypoglycaemic neuronal cell death.Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo.Elevated GFAP induces astrocyte dysfunction in caudal brain regions: A potential mechanism for hindbrain involved symptoms in type II Alexander disease.Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains.Transporters for L-glutamate: an update on their molecular pharmacology and pathological involvement.
P2860
Q24654460-85BEB46A-B5F5-4ADB-B8BA-658C48BDB46BQ24676501-C25FD568-D973-44D0-AF38-8FED49A06171Q26749567-CAF6728B-355E-41C0-A2A9-3980179F6A73Q26766290-87AC63F0-DF4E-4391-A26B-286BDF489A1FQ26778788-726F4497-9C64-400D-B3E5-5DB9AAB10ABEQ26829946-4443AA4F-59BD-4E32-A1AA-2CD2FFB61E31Q26864995-4159E6F3-555D-411C-BE9B-68D027D9AC4CQ27325399-355F8038-D1F8-4ACF-91E4-EE7C914BD6E1Q27335346-AA565431-2E0C-4938-BA80-4F8C750ED0E8Q28547125-59723960-1869-49A1-A823-A04990513749Q33470255-FD40E201-5AA5-4F72-A2A1-BCA5D1819636Q33591900-4DBEB494-59C3-4345-BF0B-88C74F3EED2BQ33758360-DA33B197-F8AB-4033-BBC1-221CA5FB9C28Q33759231-AEFA3D10-22E8-46AD-AA9B-BD054AC5C2FDQ34048502-9E2EC15E-96CC-4E54-BD6B-05134D1DC3B4Q34073426-CBECDB1C-7A66-410B-BCD8-79DD6EE698F4Q34083251-A5FF30FF-282C-45E2-998A-9077DECBDC39Q34184493-0BFB514C-1C02-43E6-ADFB-349730E98868Q34259173-5913728B-6DA7-4F54-9444-9C383B51C9DCQ34279067-7E496DA9-8DD7-40F6-AF3B-096E3D9E736CQ34333783-B3E25BC2-C27F-412A-BD78-E748E1D41EB0Q34424994-7ECDAE7F-DD8C-4C1A-AA80-E22D57BE35BAQ34460630-E061B263-8659-4E2F-BC1A-1D3FD31231DDQ34543666-FE96FF84-8E42-418E-BBF4-15899C766537Q34722256-073ADCAF-A62D-49E1-B90E-176804E94ED6Q34749647-DB8A80E1-5DDE-430F-87CB-E7A1A90D2169Q35024151-558FF822-140E-43B1-B912-3705D3521AC6Q35067815-E5A2A61E-84BD-4B59-92AE-16AFFE736135Q35331983-A38A5A63-767F-489E-983B-012F92F3E044Q35349743-54009691-78FD-4F15-B001-DECE963CE79BQ35519662-DF49FFC2-92EA-4ADC-BB79-4B221D6CBF72Q35535883-1066A6A0-1721-4372-B3F1-E04ADCB8E337Q35633662-504B88A3-D25D-4F0B-9C4A-3CC8E21BC955Q35672546-50DCA50F-2DA0-43F1-B58B-D3FBC7CF4550Q35700625-6185137B-E609-446F-B218-D2D2F59DCF09Q35744426-FA64F4BA-A894-4E52-B71C-D44609585B7AQ35800481-86B5688D-22AB-471F-9C57-B9460672196AQ36014767-2DE57D2A-612F-41A5-948A-E942B04CE46CQ36024579-30657A98-13FE-4255-B09E-E1DAF93B0626Q36052481-5DAAE25A-F711-48BE-823A-9C03FCF7A938
P2860
Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Compromised glutamate transpor ...... of cystine-glutamate exchange
@ast
Compromised glutamate transpor ...... of cystine-glutamate exchange
@en
Compromised glutamate transpor ...... of cystine-glutamate exchange
@nl
type
label
Compromised glutamate transpor ...... of cystine-glutamate exchange
@ast
Compromised glutamate transpor ...... of cystine-glutamate exchange
@en
Compromised glutamate transpor ...... of cystine-glutamate exchange
@nl
prefLabel
Compromised glutamate transpor ...... of cystine-glutamate exchange
@ast
Compromised glutamate transpor ...... of cystine-glutamate exchange
@en
Compromised glutamate transpor ...... of cystine-glutamate exchange
@nl
P2093
P3181
P1476
Compromised glutamate transpor ...... of cystine-glutamate exchange
@en
P2093
H Sontheimer
J D Rothstein
P304
10767-10777
P3181
P356
10.1523/JNEUROSCI.19-24-10767.1999
P407
P577
1999-12-01T00:00:00Z