Isoxazole analogues bind the system xc- transporter: structure-activity relationship and pharmacophore model.
about
Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signalingHigh-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma CellsSuzuki-Miyaura Cross-Coupling of Benzylic Bromides Under Microwave Conditions.System xc⁻ cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS.The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.Oxidative stress and cancer pain.Microwave accelerated synthesis of isoxazole hydrazide inhibitors of the system xc- transporter: Initial homology modelMain path and byways: non-vesicular glutamate release by system xc(-) as an important modifier of glutamatergic neurotransmission.Sulfasalazine for brain cancer fits.Use of the hydantoin isostere to produce inhibitors showing selectivity toward the vesicular glutamate transporter versus the obligate exchange transporter system x(c)(-)Ethyl 5-(4-amino-phen-yl)isoxazole-3-carboxyl-ate.The ferroptosis inducer erastin irreversibly inhibits system xc- and synergizes with cisplatin to increase cisplatin's cytotoxicity in cancer cells.
P2860
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P2860
Isoxazole analogues bind the system xc- transporter: structure-activity relationship and pharmacophore model.
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
Isoxazole analogues bind the s ...... nship and pharmacophore model.
@ast
Isoxazole analogues bind the s ...... nship and pharmacophore model.
@en
Isoxazole analogues bind the s ...... nship and pharmacophore model.
@nl
type
label
Isoxazole analogues bind the s ...... nship and pharmacophore model.
@ast
Isoxazole analogues bind the s ...... nship and pharmacophore model.
@en
Isoxazole analogues bind the s ...... nship and pharmacophore model.
@nl
prefLabel
Isoxazole analogues bind the s ...... nship and pharmacophore model.
@ast
Isoxazole analogues bind the s ...... nship and pharmacophore model.
@en
Isoxazole analogues bind the s ...... nship and pharmacophore model.
@nl
P2093
P2860
P1476
Isoxazole analogues bind the s ...... nship and pharmacophore model.
@en
P2093
Alex Blumenfeld
Brendan Twamley
David J Burkhart
Erin O'Brien
Jared K Nelson
John M Gerdes
Monika I Szabon-Watola
Nicholas R Natale
Richard J Bridges
Sarjubhai A Patel
P2860
P304
P356
10.1016/J.BMC.2009.11.001
P407
P577
2009-11-10T00:00:00Z