CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux
about
Identification, characterization and leucocyte expression of Siglec-10, a novel human sialic acid-binding receptorIdentification of a family of Fc receptor homologs with preferential B cell expressionSiglecs in the immune systemSiglecs as sensors of self in innate and adaptive immune responsesSiglecs and immune regulationCD22 and Siglec-G in B cell function and toleranceThe Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cellsCD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1CD22: an inhibitory enigmaFCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signalingCarabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunitySialic acid binding domains of CD22 are required for negative regulation of B cell receptor signalingAmplified B lymphocyte CD40 signaling drives regulatory B10 cell expansion in mice.Differential roles for the inositol phosphatase SHIP in the regulation of macrophages and lymphocytes.Targeting CD22 with the monoclonal antibody epratuzumab modulates human B-cell maturation and cytokine production in response to Toll-like receptor 7 (TLR7) and B-cell receptor (BCR) signalingNew functions for the sialic acid-binding adhesion molecule CD22, a member of the growing family of Siglecs.Molecular underpinning of B-cell anergy.Ig beta tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization.CD19, CD21, and CD22: multifaceted response regulators of B lymphocyte signal transduction.Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosusTransmembrane adapters: attractants for cytoplasmic effectors.B Lymphocyte signaling established by the CD19/CD22 loop regulates autoimmunity in the tight-skin mouse.Isotype control of B cell signaling.Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptorsFCRL regulation in innate-like B cells.Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling.Ca(2+) signaling in antigen receptor-activated B lymphocytes.CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling.The Myc-miR-17-92 axis amplifies B-cell receptor signaling via inhibition of ITIM proteins: a novel lymphomagenic feed-forward loop.EndoU is a novel regulator of AICD during peripheral B cell selection.A reevaluation of CD22 expression in human lung cancer.Aberrant antibody affinity selection in SHIP-deficient B cells.Besides an ITIM/SHP-1-dependent pathway, CD22 collaborates with Grb2 and plasma membrane calcium-ATPase in an ITIM/SHP-1-independent pathway of attenuation of Ca2+i signal in B cells.CD22 and Siglec-G regulate inhibition of B-cell signaling by sialic acid ligand binding and control B-cell tolerance.Engagement of CD22 on B cells with the monoclonal antibody epratuzumab stimulates the phosphorylation of upstream inhibitory signals of the B cell receptor.Novel binding site for Src homology 2-containing protein-tyrosine phosphatase-1 in CD22 activated by B lymphocyte stimulation with antigen.A Comprehensive Immunoreceptor Phosphotyrosine-based Signaling Network Revealed by Reciprocal Protein-Peptide Array Screening.Pharmacological targeting of phosphoinositide lipid kinases and phosphatases in the immune system: success, disappointment, and new opportunities.CD19 amplification of B lymphocyte Ca2+ responses: a role for Lyn sequestration in extinguishing negative regulation.CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity.
P2860
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P2860
CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
CD22 forms a quaternary comple ...... receptor-induced calcium flux
@ast
CD22 forms a quaternary comple ...... receptor-induced calcium flux
@en
CD22 forms a quaternary comple ...... receptor-induced calcium flux
@nl
type
label
CD22 forms a quaternary comple ...... receptor-induced calcium flux
@ast
CD22 forms a quaternary comple ...... receptor-induced calcium flux
@en
CD22 forms a quaternary comple ...... receptor-induced calcium flux
@nl
prefLabel
CD22 forms a quaternary comple ...... receptor-induced calcium flux
@ast
CD22 forms a quaternary comple ...... receptor-induced calcium flux
@en
CD22 forms a quaternary comple ...... receptor-induced calcium flux
@nl
P2093
P2860
P921
P3181
P356
P1476
CD22 forms a quaternary comple ...... receptor-induced calcium flux
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M001892200
P407
P577
2000-06-09T00:00:00Z