A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase
about
A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cellsRegulation of human neutrophil-mediated cartilage proteoglycan degradation by phosphatidylinositol-3-kinaseTumour necrosis factor-alpha activation of protein kinase B in WEHI-164 cells is accompanied by increased phosphorylation of Ser473, but not Thr308Transient mechanoactivation of neutral sphingomyelinase in caveolae to generate ceramideActivation of eNOS in rat portal hypertensive gastric mucosa is mediated by TNF-alpha via the PI 3-kinase-Akt signaling pathwayNerve growth factor enhances the excitability of rat sensory neurons through activation of the atypical protein kinase C isoform, PKMζ.Regulation of PI-3-Kinase and Akt Signaling in T Lymphocytes and Other Cells by TNFR Family MoleculesTumor necrosis factor-alpha induces stress fiber formation through ceramide production: role of sphingosine kinase.Sesamin inhibits macrophage-induced vascular endothelial growth factor and matrix metalloproteinase-9 expression and proangiogenic activity in breast cancer cells.Cell-permeable ceramides preferentially inhibit coated vesicle formation and exocytosis in Chinese hamster ovary compared with Madin-Darby canine kidney cells by preventing the membrane association of ADP-ribosylation factor.Ceramide induces a loss in cytosolic peroxide levels in mononuclear cells.Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-alpha cytotoxicity.Transactivation of ErbB2 and ErbB3 by tumor necrosis factor-alpha and anisomycin leads to impaired insulin signaling through serine/threonine phosphorylation of IRS proteins.The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation.
P2860
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P2860
A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A novel pathway for tumor necr ...... phosphatidylinositol 3-kinase
@ast
A novel pathway for tumor necr ...... phosphatidylinositol 3-kinase
@en
A novel pathway for tumor necr ...... phosphatidylinositol 3-kinase
@nl
type
label
A novel pathway for tumor necr ...... phosphatidylinositol 3-kinase
@ast
A novel pathway for tumor necr ...... phosphatidylinositol 3-kinase
@en
A novel pathway for tumor necr ...... phosphatidylinositol 3-kinase
@nl
prefLabel
A novel pathway for tumor necr ...... phosphatidylinositol 3-kinase
@ast
A novel pathway for tumor necr ...... phosphatidylinositol 3-kinase
@en
A novel pathway for tumor necr ...... phosphatidylinositol 3-kinase
@nl
P2093
P2860
P356
P1476
A novel pathway for tumor necr ...... phosphatidylinositol 3-kinase
@en
P2093
P2860
P304
P356
10.1074/JBC.274.18.12722
P407
P577
1999-04-30T00:00:00Z