about
Werner SyndromeKu complex interacts with and stimulates the Werner proteinThe spectrum of WRN mutations in Werner syndrome patientsMutations in the WRN gene in mice accelerate mortality in a p53-null backgroundMechanism of Werner DNA helicase: POT1 and RPA stimulates WRN to unwind beyond gaps in the translocating strand.WRN is recruited to damaged telomeres via its RQC domain and tankyrase1-mediated poly-ADP-ribosylation of TRF1.WRN helicase expression in Werner syndrome cell linesWerner syndrome gene variants in human sarcomasLoss of Werner syndrome protein function promotes aberrant mitotic recombination.Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae.Catalytic activities of Werner protein are affected by adduction with 4-hydroxy-2-nonenalCellular Werner phenotypes in mice expressing a putative dominant-negative human WRN geneComplex SNP-based haplotypes in three human helicases: implications for cancer association studies.Identification and characterization of a Drosophila ortholog of WRN exonuclease that is required to maintain genome integrity.From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing.Homozygosity for the WRN Helicase-Inactivating Variant, R834C, does not confer a Werner syndrome clinical phenotype.Human RECQ Helicase Pathogenic Variants, Population Variation and "Missing" Diseases.Divergent cellular phenotypes of human and mouse cells lacking the Werner syndrome RecQ helicase.
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999 թուականին հրատարակուած գիտական յօդուած
@hyw
1999 թվականին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
WRN mutations in Werner syndrome
@ast
WRN mutations in Werner syndrome
@en
WRN mutations in Werner syndrome
@nl
type
label
WRN mutations in Werner syndrome
@ast
WRN mutations in Werner syndrome
@en
WRN mutations in Werner syndrome
@nl
prefLabel
WRN mutations in Werner syndrome
@ast
WRN mutations in Werner syndrome
@en
WRN mutations in Werner syndrome
@nl
P2093
P1433
P1476
WRN mutations in Werner syndrome
@en
P2093
P356
10.1002/(SICI)1098-1004(1999)13:4<271::AID-HUMU2>3.3.CO;2-H
P407
P577
1999-01-01T00:00:00Z