Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity
about
Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress responseInhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor proteinTransforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteinsWWOX: a candidate tumor suppressor gene involved in multiple tumor typesFunctional association between Wwox tumor suppressor protein and p73, a p53 homologTargeted deletion of Wwox reveals a tumor suppressor functionTransforming growth factor-beta1 blocks the enhancement of tumor necrosis factor cytotoxicity by hyaluronidase Hyal-2 in L929 fibroblasts.Structure and apoptotic function of p73Tumor Suppressor WWOX Contributes to the Elimination of Tumorigenic Cells in Drosophila melanogasterTumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage ResponseHYAL-2-WWOX-SMAD4 Signaling in Cell Death and Anticancer ResponseWWOX, the chromosomal fragile site FRA16D spanning gene: its role in metabolism and contribution to cancerJNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosisWWOX, the common chromosomal fragile site, FRA16D, cancer geneDown-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's diseaseBacterial redox protein azurin, tumor suppressor protein p53, and regression of cancer.Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in ratsThe non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppressionTGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.Integrating Diverse Types of Genomic Data to Identify Genes that Underlie Adverse Pregnancy PhenotypesAnalysis of families with common variable immunodeficiency (CVID) and IgA deficiency suggests linkage of CVID to chromosome 16q17beta-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo.Expression of hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in serous ovarian carcinomas: inverse correlation between HYAL1 and hyaluronan contentComplement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells.Image-based assessment of growth and signaling changes in cancer cells mediated by direct cell-cell contact.Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma.Expanding the genetic basis of copy number variation in familial breast cancer.NQO1 stabilizes p53 through a distinct pathway.WWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies.WWOX mRNA expression profile in epithelial ovarian cancer supports the role of WWOX variant 1 as a tumour suppressor, although the role of variant 4 remains unclear.Oncosuppressor proteins of fragile sites are reduced in cervical cancer.Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species.Zfra is a small wizard in the mitochondrial apoptosisCommon fragile site tumor suppressor genes and corresponding mouse models of cancer.miR-134 induces oncogenicity and metastasis in head and neck carcinoma through targeting WWOX gene.Correlation of WWOX, RUNX2 and VEGFA protein expression in human osteosarcomaWW domain-containing oxidoreductase in neuronal injury and neurological diseases.Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.WWOX suppresses prostate cancer cell progression through cyclin D1-mediated cell cycle arrest in the G1 phase.
P2860
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P2860
Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Hyaluronidase induction of a W ...... r necrosis factor cytotoxicity
@ast
Hyaluronidase induction of a W ...... r necrosis factor cytotoxicity
@en
Hyaluronidase induction of a W ...... r necrosis factor cytotoxicity
@nl
type
label
Hyaluronidase induction of a W ...... r necrosis factor cytotoxicity
@ast
Hyaluronidase induction of a W ...... r necrosis factor cytotoxicity
@en
Hyaluronidase induction of a W ...... r necrosis factor cytotoxicity
@nl
prefLabel
Hyaluronidase induction of a W ...... r necrosis factor cytotoxicity
@ast
Hyaluronidase induction of a W ...... r necrosis factor cytotoxicity
@en
Hyaluronidase induction of a W ...... r necrosis factor cytotoxicity
@nl
P2093
P2860
P356
P1476
Hyaluronidase induction of a W ...... r necrosis factor cytotoxicity
@en
P2093
P2860
P304
P356
10.1074/JBC.M007140200
P407
P577
2001-02-02T00:00:00Z