about
Implications of NQO1 in cancer therapyQuercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development StrategyNQO1 C609T polymorphism and colorectal cancer susceptibility: a meta-analysisNAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotectorThe NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysisA mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73Bacterial redox protein azurin, tumor suppressor protein p53, and regression of cancer.Cytoprotection "gone astray": Nrf2 and its role in cancerImpairment of antioxidant defenses as a contributor to arsenite-induced cell transformationAn NQO1-initiated and p53-independent apoptotic pathway determines the anti-tumor effect of tanshinone IIA against non-small cell lung cancerRobust concentration and frequency control in oscillatory homeostatsLAS0811: from combinatorial chemistry to activation of antioxidant response element.NAD(P)H quinone oxidoreductase protects TAp63gamma from proteasomal degradation and regulates TAp63gamma-dependent growth arrest.TP53, MDM2, NQO1, and susceptibility to cervical cancer.PIG3 Regulates p53 Stability by Suppressing Its MDM2-Mediated UbiquitinationInhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.Multiple distinct molecular mechanisms influence sensitivity and resistance to MDM2 inhibitors in adult acute myelogenous leukemia.NAD(P)H:quinone oxidoreductase 1 is induced by progesterone in cardiomyocytes.NAD(P)H:quinone oxidoreductase 1-compromised human bone marrow endothelial cells exhibit decreased adhesion molecule expression and CD34+ hematopoietic cell adhesion.A functional NQO1 609C>T polymorphism and risk of gastrointestinal cancers: a meta-analysis.Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1.Increased NQO1 but not c-MET and survivin expression in non-small cell lung carcinoma with KRAS mutationsP53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1A functional NQO1 609C>T polymorphism and risk of hepatocellular carcinoma in a Chinese population.The NQO1 allelic frequency in hindu population of central India varies from that of other Asian populations.Clinical significance of NQO1 polymorphism and expression of p53, SOD2, PARP1 in limited-stage small cell lung cancerAmifostine alleviates radiation-induced lethal small bowel damage via promotion of 14-3-3σ-mediated nuclear p53 accumulationPrognostic significance of NQO1 expression in intrahepatic cholangiocarcinoma.The curcuminoid CLEFMA selectively induces cell death in H441 lung adenocarcinoma cells via oxidative stress.NRH:quinone oxidoreductase 2-deficient mice are highly susceptible to radiation-induced B-cell lymphomasInhibition of p53-induced apoptosis without affecting expression of p53-regulated genes.p53, aerobic metabolism, and cancer.Calcium and reactive oxygen species in acute pancreatitis: friend or foe?Long term effect of curcumin in restoration of tumour suppressor p53 and phase-II antioxidant enzymes via activation of Nrf2 signalling and modulation of inflammation in prevention of cancer.The NQO1*2/*2 polymorphism is associated with poor overall survival in patients following resection of stages II and IIIa non-small cell lung cancer.Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53.A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone.Quinone reductases multitasking in the metabolic world.Geldanamycin, a ligand of heat shock protein 90, inhibits the replication of herpes simplex virus type 1 in vitro.Mutant p53 confers chemoresistance in non-small cell lung cancer by upregulating Nrf2
P2860
Q26783702-E6B3264F-E39C-4B32-9C33-BD6B6199C07FQ28076840-74BF1C29-E315-4D11-B5AE-5988DBCFD11EQ28249084-DFC0D4B7-6398-4CA4-83DE-90A3FE2A438AQ28278566-7BB11DC0-5CDD-459B-AD76-4F5EC80D7C61Q28294622-1B27C63B-EBBB-4C07-AD5F-ED13A46F2BB8Q28305429-EC06B1F1-96B8-4159-8F45-5DD1F85A0789Q28387398-B7789FB3-7B01-43F2-B74B-4E04EBA63BBCQ28393784-0A8C78E5-22AB-449E-A0D3-599217EF907FQ28396493-7686BC59-BE64-4D1F-AD98-7205AC6D858BQ28481620-FDC4A65F-FDC5-486A-89D1-E6E670EACC02Q28543096-928086FE-608F-4FF5-847F-7366E3962943Q33507900-E34027A1-73CD-46D1-8444-D72561309699Q33627637-3A3F50E9-F81A-49E5-AA4A-E50E2DF79F34Q33723403-62705671-B1E5-4AEF-88DD-B53F9E1CF300Q33878303-0318163E-9813-4DFC-9993-6B14F715ACD1Q33936687-BA6E52C1-1665-4965-89B1-B57246FCC2DEQ33997232-E87AAA15-FF89-4B9C-970C-091FD8670197Q34025654-F0122110-755F-485D-90F9-FF3F12B070CDQ34028119-31C7B02E-58E7-4C4D-A121-4595F185E778Q34137818-F8ECE719-ADD5-4986-B83B-304BADC0391BQ34191852-0F93004D-9332-4332-9CA3-CA16095F1B36Q34348237-DF6AD370-8DC4-49D3-A4C9-7D9BBD19DAD0Q34390794-F2714D18-67DA-4A36-898D-31A1F2E347CDQ34413452-10F57C47-C423-4073-AD7A-132C3B781D14Q34436537-DCA3D88E-5CF9-4E40-B832-A969D9A9225DQ34502009-7A1A2C75-5C17-4524-B7A2-127A099B5C64Q34654628-0E0E4795-68F9-4DCA-AED7-786C3AD6B129Q34976425-AFFD811A-7BBF-47E2-AEC4-A4B409125B65Q35032472-A17C710D-C78C-4E62-9FA3-416CFF97AC32Q35055410-15CAEE10-B68A-420E-9344-257433C0B423Q35144075-33C00539-8CEB-426F-B896-848A59CE0512Q35151326-30A12223-9D3F-4CDD-97B8-F0EC077515BBQ35245361-FFFC36EC-CBC1-41C4-A517-598B9F7D88A7Q35362591-174CD3F7-F5A1-4C82-8E1D-3FD58B6B2B41Q35536290-9023FF46-C9A2-4797-8205-BBA740CC3925Q35747115-455D8D1D-3DBD-423D-91B5-4B8E3FB131F3Q35907697-A7129D4B-6AB0-4E12-A407-8DE49902BF7CQ35956182-99A2B0A3-3123-4A10-87A3-3A2D6FFB315CQ36491843-1F8D57DE-F334-4EE0-AC01-4C880DE134AFQ36561564-2F46F4C0-F4BA-4174-9ACE-0C096243ECEA
P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
NQO1 stabilizes p53 through a distinct pathway.
@ast
NQO1 stabilizes p53 through a distinct pathway.
@en
NQO1 stabilizes p53 through a distinct pathway.
@nl
type
label
NQO1 stabilizes p53 through a distinct pathway.
@ast
NQO1 stabilizes p53 through a distinct pathway.
@en
NQO1 stabilizes p53 through a distinct pathway.
@nl
prefLabel
NQO1 stabilizes p53 through a distinct pathway.
@ast
NQO1 stabilizes p53 through a distinct pathway.
@en
NQO1 stabilizes p53 through a distinct pathway.
@nl
P2093
P2860
P356
P1476
NQO1 stabilizes p53 through a distinct pathway.
@en
P2093
Joseph Lotem
Rachel Kama
Yosef Shaul
P2860
P304
P356
10.1073/PNAS.052706799
P407
P577
2002-02-26T00:00:00Z