A 54-kDa fragment of the Poly(A)-specific ribonuclease is an oligomeric, processive, and cap-interacting Poly(A)-specific 3' exonuclease
about
CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase.Identification of a human cytoplasmic poly(A) nuclease complex stimulated by poly(A)-binding proteinUNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinantThe scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatasesNuclear deadenylation/polyadenylation factors regulate 3' processing in response to DNA damage.Functional analysis of mRNA scavenger decapping enzymes.Tristetraprolin and its family members can promote the cell-free deadenylation of AU-rich element-containing mRNAs by poly(A) ribonucleaseThe RRM domain of poly(A)-specific ribonuclease has a noncanonical binding site for mRNA cap analog recognitionThe activity and selectivity of fission yeast Pop2p are affected by a high affinity for Zn2+ and Mn2+ in the active siteCoordination of divalent metal ions in the active site of poly(A)-specific ribonucleaseISG20L2, a novel vertebrate nucleolar exoribonuclease involved in ribosome biogenesisThe mRNA cap structure stimulates rate of poly(A) removal and amplifies processivity of degradationIdentification of the active site of poly(A)-specific ribonuclease by site-directed mutagenesis and Fe(2+)-mediated cleavageMessenger RNA turnover in eukaryotes: pathways and enzymesAn integrated in silico approach to design specific inhibitors targeting human poly(a)-specific ribonucleaseDynamical insight into Caenorhabditis elegans eIF4E recognition specificity for mono-and trimethylated structures of mRNA 5' cap.Poly(A)-specific ribonuclease is a nuclear ribosome biogenesis factor involved in human 18S rRNA maturation.The major mRNA-associated protein YB-1 is a potent 5' cap-dependent mRNA stabilizerIn vitro analysis of RNA degradation catalyzed by deadenylase enzymes.Structural insight into poly(A) binding and catalytic mechanism of human PARN.mRNA instability in the nucleus due to a novel open reading frame element is a major determinant of the narrow tissue specificity of folate receptor alpha.Dissimilar roles of the four conserved acidic residues in the thermal stability of poly(A)-specific ribonuclease.A deadenylase assay by size-exclusion chromatography.Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimmingVersatile applications of transcriptional pulsing to study mRNA turnover in mammalian cellsPARN deadenylase is involved in miRNA-dependent degradation of TP53 mRNA in mammalian cells.A feedback mechanism between PLD and deadenylase PARN for the shortening of eukaryotic poly(A) mRNA tails that is deregulated in cancer cells.Poly(A)-specific ribonuclease (PARN): an allosterically regulated, processive and mRNA cap-interacting deadenylase.Cap-binding complex (CBC).Deadenylation: enzymes, regulation, and functional implications.Identification of multiple RNA features that influence CCR4 deadenylation activity.Inhibition of Klenow DNA polymerase and poly(A)-specific ribonuclease by aminoglycosidesAtHESPERIN: a novel regulator of circadian rhythms with poly(A)-degrading activity in plants.Recognition of adenosine residues by the active site of poly(A)-specific ribonuclease.Poly(A)-specific ribonuclease mediates 3'-end trimming of Argonaute2-cleaved precursor microRNAs.Degradation of hsp70 and other mRNAs in Drosophila via the 5' 3' pathway and its regulation by heat shock.Bone marrow failure and developmental delay caused by mutations in poly(A)-specific ribonuclease (PARN).Nucleolin phosphorylation regulates PARN deadenylase activity during cellular stress response.How miRs and mRNA deadenylases could post-transcriptionally regulate expression of tumor-promoting protein PLD.
P2860
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P2860
A 54-kDa fragment of the Poly(A)-specific ribonuclease is an oligomeric, processive, and cap-interacting Poly(A)-specific 3' exonuclease
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
A 54-kDa fragment of the Poly( ...... oly(A)-specific 3' exonuclease
@ast
A 54-kDa fragment of the Poly( ...... oly(A)-specific 3' exonuclease
@en
A 54-kDa fragment of the Poly( ...... oly(A)-specific 3' exonuclease
@nl
type
label
A 54-kDa fragment of the Poly( ...... oly(A)-specific 3' exonuclease
@ast
A 54-kDa fragment of the Poly( ...... oly(A)-specific 3' exonuclease
@en
A 54-kDa fragment of the Poly( ...... oly(A)-specific 3' exonuclease
@nl
prefLabel
A 54-kDa fragment of the Poly( ...... oly(A)-specific 3' exonuclease
@ast
A 54-kDa fragment of the Poly( ...... oly(A)-specific 3' exonuclease
@en
A 54-kDa fragment of the Poly( ...... oly(A)-specific 3' exonuclease
@nl
P2093
P2860
P356
P1476
A 54-kDa fragment of the Poly( ...... oly(A)-specific 3' exonuclease
@en
P2093
P2860
P304
P356
10.1074/JBC.M001705200
P407
P577
2000-08-04T00:00:00Z