Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms
about
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3PIKfyve: Partners, significance, debates and paradoxesHelix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease inductionAn amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinerySgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle.High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site.Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and glucocorticoid-induced protein kinase in vivoUbiquitin modification of serum and glucocorticoid-induced protein kinase-1 (SGK-1)SGK1: The Dark Side of PI3K Signaling.Aldosterone signaling pathway across the nuclear envelopeThe stress hormone corticosterone increases synaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors via serum- and glucocorticoid-inducible kinase (SGK) regulation of the GDI-Rab4 complexExpression of serum- and glucocorticoid-regulated kinase 1 and its association with clinicopathological factors and the survival of patients with adenocarcinoma of the esophagogastric junction.Characterization of the regulation of renal Na+/H+ exchanger NHE3 by insulin.WNK1 activates SGK1 to regulate the epithelial sodium channel.Plasma corticosterone activates SGK1 and induces morphological changes in oligodendrocytes in corpus callosum.Dot1a contains three nuclear localization signals and regulates the epithelial Na+ channel (ENaC) at multiple levels.Kinase requirements in human cells: V. Synthetic lethal interactions between p53 and the protein kinases SGK2 and PAK3Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.Impaired renal Na(+) retention in the sgk1-knockout mouse.Phosphorylation of nicastrin by SGK1 leads to its degradation through lysosomal and proteasomal pathways.Glucocorticoid adrenal steroids and glucocorticoid-inducible kinase isoforms in the regulation of GluR6 expression.Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome.SGK3 is an estrogen-inducible kinase promoting estrogen-mediated survival of breast cancer cells.Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling.Concerted roles of SGK1 and the Na+/H+ exchanger regulatory factor 2 (NHERF2) in regulation of NHE3.mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel.Unique gene expression profile associated with an early-onset multiple endocrine neoplasia (MEN1)-associated pituitary adenomaNovel role for SGK3 in glucose homeostasis revealed in SGK3/Akt2 double-null miceNegative regulation of SEK1 signaling by serum- and glucocorticoid-inducible protein kinase 1.Inhibition of serum- and glucocorticoid-inducible kinase 1 enhances TLR-mediated inflammation and promotes endotoxin-driven organ failure.Insulin's expanding control of forkheads.Effect of acute physiological hyperinsulinemia on gene expression in human skeletal muscle in vivo.Regulation of differential pro- and anti-apoptotic signaling by glucocorticoids.Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegansAkt2 and SGK3 are both determinants of postnatal hair follicle development.Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway.Glucocorticoids can activate the alpha-ENaC gene promoter independently of SGK1.The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications.Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development.Leucine-Rich Repeat Kinase 2 (Lrrk2)-Sensitive Na+/K+ ATPase Activity in Dendritic Cells
P2860
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P2860
Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Regulation and physiological r ...... nduced protein kinase isoforms
@ast
Regulation and physiological r ...... nduced protein kinase isoforms
@en
Regulation and physiological r ...... nduced protein kinase isoforms
@nl
type
label
Regulation and physiological r ...... nduced protein kinase isoforms
@ast
Regulation and physiological r ...... nduced protein kinase isoforms
@en
Regulation and physiological r ...... nduced protein kinase isoforms
@nl
altLabel
Regulation and Physiological R ...... nduced Protein Kinase Isoforms
@en
prefLabel
Regulation and physiological r ...... nduced protein kinase isoforms
@ast
Regulation and physiological r ...... nduced protein kinase isoforms
@en
Regulation and physiological r ...... nduced protein kinase isoforms
@nl
P2860
P1476
Regulation and Physiological R ...... nduced Protein Kinase Isoforms
@en
P2093
P2860
P356
10.1126/SCISIGNAL.1082001RE17
10.1126/STKE.2001.108.RE17
P407
P577
2001-11-13T00:00:00Z