Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1epsilon - sprookjes - yvandenbroek - TriplyDB

Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1epsilon

Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1epsilon

http://www.wikidata.org/entity/Q28211035

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The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis Association and regulation of casein kinase 2 activity by adenomatous polyposis coli protein Wnt/beta-catenin signaling and small molecule inhibitors Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex The links between axin and carcinogenesis A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway beta-catenin destruction complex: insights and questions from a structural perspective The β-catenin destruction complex Human APC sequesters β-catenin even in the absence of GSK-3β in a Drosophila model Protein kinase C delta negatively modulates canonical Wnt pathway and cell proliferation in colon tumor cell lines Casein kinase Iepsilon modulates the signaling specificities of dishevelled Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs Adenomatous polyposis coli regulates endothelial cell migration independent of roles in beta-catenin signaling and cell-cell adhesion.A molecular genetics laboratory course applying bioinformatics and cell biology in the context of original research.Modeling the effect of APC truncation on destruction complex function in colorectal cancer cells Regulation of Wnt/beta-catenin signaling by protein kinases The first armadillo repeat is involved in the recognition and regulation of beta-catenin phosphorylation by protein kinase CK1 A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destruction Reversible modification of adenomatous polyposis coli (APC) with K63-linked polyubiquitin regulates the assembly and activity of the β-catenin destruction complex.The two SAMP repeats and their phosphorylation state in Drosophila Adenomatous polyposis coli-2 play mechanistically distinct roles in negatively regulating Wnt signaling.Phospho-regulation of Beta-catenin adhesion and signaling functions.Wnt/beta-catenin signaling: new (and old) players and new insights Role of adenomatous polyposis coli (APC) and microtubules in directional cell migration and neuronal polarization.The terminal region of beta-catenin promotes stability by shielding the Armadillo repeats from the axin-scaffold destruction complex.Role of APC and its binding partners in regulating microtubules in mitosis.Diversity of axin in signaling pathways and its relation to colorectal cancer.Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles.The way Wnt works: components and mechanism.Toward a quantitative understanding of the Wnt/β-catenin pathway through simulation and experiment.Regulation of Wnt/β-catenin signaling by posttranslational modifications Biological functions of casein kinase 1 isoforms and putative roles in tumorigenesis.Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance.CK1 in Developmental Signaling: Hedgehog and Wnt.Molecular regulation and pharmacological targeting of the β-catenin destruction complex.Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila.Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription.Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.

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P2860

Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1epsilon

http://www.wikidata.org/entity/Q28211035

description

2001 nî lūn-bûn

@nan

2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Axin-dependent phosphorylation ...... ated by casein kinase 1epsilon

@ast

Axin-dependent phosphorylation ...... ated by casein kinase 1epsilon

@en

Axin-dependent phosphorylation ...... ated by casein kinase 1epsilon

@nl

type

label

Axin-dependent phosphorylation ...... ated by casein kinase 1epsilon

@ast

Axin-dependent phosphorylation ...... ated by casein kinase 1epsilon

@en

Axin-dependent phosphorylation ...... ated by casein kinase 1epsilon

@nl

prefLabel

Axin-dependent phosphorylation ...... ated by casein kinase 1epsilon

@ast

Axin-dependent phosphorylation ...... ated by casein kinase 1epsilon

@en

Axin-dependent phosphorylation ...... ated by casein kinase 1epsilon

@nl

P1433

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P2860

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P3181

P356

P1433

Journal of Biological Chemistry

P1476

Axin-dependent phosphorylation ...... ated by casein kinase 1epsilon

@en

P2093

B Rubinfeld

http://www.w3.org/2001/XMLSchema#string

D A Tice

http://www.w3.org/2001/XMLSchema#string

P Polakis

http://www.w3.org/2001/XMLSchema#string

P2860

DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin.

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

Association of the APC gene product with beta-catenin

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.

Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

P304

39037-45

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scholarly article

P3181

2300142

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P356

10.1074/JBC.M105148200

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P407

P433

42

http://www.w3.org/2001/XMLSchema#string

P478

276

http://www.w3.org/2001/XMLSchema#string

P577

2001-10-19T00:00:00Z

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P698

11487578

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P921

phosphorylation