Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection
about
Coevolution of T-cell receptors with MHC and non-MHC ligandsTurned on by danger: activation of CD1d-restricted invariant natural killer T cellsHard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptabilityAllelic polymorphism in the T cell receptor and its impact on immune responsesA highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHCStructural Basis of Specificity and Cross-Reactivity in T Cell Receptors Specific for Cytochrome c-I-EStructural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responsesA Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR ConformersT-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergyV 2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigenT Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility ComplexStructural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4A Conserved Hydrophobic Patch on Vβ Domains Revealed by TCRβ Chain Crystal Structures: Implications for Pre-TCR DimerizationT-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex InteractionsEffect of CDR3 Sequences and Distal V Gene Residues in Regulating TCR-MHC Contacts and Ligand Specificityαβ T cell receptors that do not undergo major histocompatibility complex-specific thymic selection possess antibody-like recognition specificitiesMHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selectionReconciling views on T cell receptor germline bias for MHCStructural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by Vα CDR3T cells and their eons-old obsession with MHCLck availability during thymic selection determines the recognition specificity of the T cell repertoireT cell receptor bias for MHC: co-evolution or co-receptors?How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoirePeriplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA.Structural biology of the T-cell receptor: insights into receptor assembly, ligand recognition, and initiation of signaling.Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentationTwo mechanisms that account for major histocompatibility complex restriction of T cells.The basis for limited specificity and MHC restriction in a T cell receptor interface.A novel T cell subset with trans-rearranged Vγ-Cβ TCRs shows Vβ expression is dispensable for lineage choice and MHC restrictionDesign of T-cell receptor libraries with diverse binding properties to examine adoptive T-cell responses.MAIT cell recognition of MR1 on bacterially infected and uninfected cells.Alloreactivity is limited by the endogenous peptide repertoireGeneration of MHC class II-peptide ligands for CD4 T-cell allorecognition of MHC class II molecules.Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexes.Self/Nonself-Immune Recognition and Signaling: A new journal tackles a problem at the center of immunological science.Molecular identification of an MHC-independent ligand recognized by a human {alpha}/{beta} T-cell receptor.Properties of MHC class I presented peptides that enhance immunogenicityAnalyses of the TCR repertoire of MHC class II-restricted innate CD4⁺ T cellsNonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions.
P2860
Q26797242-8F69C302-EA56-425F-BCCC-CF9807441684Q26825059-34A340AA-98AA-4E04-B7B3-F2E48545F1A8Q27661747-50C74E8B-ED5A-4174-B184-E4EF66A45022Q27662550-A7B1F56C-9F87-4ACB-AAC3-5D4C0BFF9940Q27666431-A8E32C25-61D4-40E7-ABF5-66DAA4BA078CQ27667507-E0357650-5450-47B0-9B64-E5C9296B51A2Q27667972-470B8700-1D59-45BA-8051-8B67F4D2A63EQ27670467-53DBF4C5-0D68-4E18-8520-CD9BF80ED2E2Q27674693-B8B645B6-56EA-48AD-BA1E-F3E392403763Q27675443-98A871A9-A4DB-4461-8D5E-969BCEBAA9E6Q27675661-12C6BA8A-3651-4520-BC74-36012391F2E5Q27676742-938843C7-5699-423E-B92E-6332D1F9A01BQ27678108-2DF438CA-231A-4194-A712-08B2FC63C5F0Q27678955-DCD7D4C1-F0CE-4FA7-B85F-29591D354B38Q27680546-AC121065-42EF-4BF1-B3CD-8AD0F59A5EDFQ27683690-0446646F-850C-4363-89D4-E0B11FC1B090Q28256382-0B595267-8938-4863-97E5-BCDE75AE7623Q28270572-FB0E3E73-BA4D-4684-BA40-F265A6A828B1Q28270580-19FCB34C-7FE9-4D6F-A1A4-ECF5DE17915BQ28273830-6EC18A40-9DDC-4505-ACE3-7BF748094B4AQ28276597-1E82C408-BB3B-4722-9ED8-45BD6AC0B3F4Q28298459-D2520223-74FD-4B28-8FB6-01B6B90902F6Q29037684-D35DFA0C-F8E3-4123-9693-1B742520D3BFQ33362590-67299F9B-F15D-4E15-B5F1-727F11DFA9E9Q33529299-E2F0521B-15D4-406C-B27B-A7463CBFAD58Q33752200-480D67DB-1DE9-40EB-A5DC-8D44422DCA86Q34063488-C5E8E3FA-6CC7-476A-8A48-A72F0167F3E3Q34167226-62DED540-2B47-49BF-8483-805272E92E41Q34348673-CF44CCC7-C25B-4C00-912B-08506559C07BQ34389870-F0683B1F-917C-435C-9F06-747AF8F11D8EQ34439729-52B6D3C6-3EBA-469C-9917-EF0990CABC97Q34558727-C379A0AD-E782-473C-B225-955DE8AFF718Q34621287-4803C328-EE17-4FF9-943F-E66467FF9C03Q34893634-C5C4398F-E945-4E64-8E18-DEE34822859DQ34953926-52A96A7F-4195-49D7-8500-D08784FA681BQ34967399-3FD71394-18DE-4ED1-91F3-953C7E297ED3Q35001609-EF2415EF-12A4-47B6-87AD-3CD356589EF6Q35034097-5005701F-54B9-427F-893D-D065599E0E51Q35152971-1659C1B8-8572-4F05-A764-C000E60DC3DEQ35170922-51622DFE-41EF-4D6F-9592-DD62095020AD
P2860
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection
@ast
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection
@en
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection
@nl
type
label
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection
@ast
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection
@en
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection
@nl
prefLabel
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection
@ast
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection
@en
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection
@nl
P2860
P50
P3181
P356
P1433
P1476
Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection
@en
P2860
P2888
P304
P3181
P356
10.1038/NATURE07812
P407
P577
2009-04-23T00:00:00Z
P5875
P6179
1017171182