Latent transforming growth factor-beta: structural features and mechanisms of activation
about
Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-betaResidues essential for plasminogen binding by the cation-independent mannose 6-phosphate receptorBinding of urokinase-type plasminogen activator receptor (uPAR) to the mannose 6-phosphate/insulin-like growth factor II receptor: contrasting interactions of full-length and soluble forms of uPARTGF-β2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestineThe latent transforming growth factor beta binding protein (LTBP) familyCell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesisInteractions between growth factors and integrins: latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1Pathways for aberrant angiogenesis in pancreatic cancerA cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactionsThe Role of Lymphocytes in Radiotherapy-Induced Adverse Late Effects in the Lungαv integrins: key regulators of tissue fibrosisIntertwining of Activin A and TGFβ Signaling: Dual Roles in Cancer Progression and Cancer Cell InvasionInflammation and Alzheimer's diseaseMicrofibrillar proteins MAGP-1 and MAGP-2 induce Notch1 extracellular domain dissociation and receptor activationPhosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammationHealing of burn wounds in transgenic mice overexpressing transforming growth factor-beta 1 in the epidermisSubcellular localization of (latent) transforming growth factor beta and the latent TGF-beta binding protein in rat hepatocytes and hepatic stellate cellsPDGF-BB induces expression of LTBP-1 but not TGF-beta1 in a rat cirrhotic fat storing cell lineTransforming growth factor-β: activation by neuraminidase and role in highly pathogenic H5N1 influenza pathogenesis.Grafting and early expression of growth factors from adipose-derived stem cells transplanted into the cochlea, in a Guinea pig model of acoustic trauma.Demonstration of the interaction of transforming growth factor beta 2 and type X collagen using a modified tandem affinity purification tag.Transgenic over-expression of plasminogen activator inhibitor-1 results in age-dependent and gender-specific increases in bone strength and mineralization.Rationale and design of a randomized clinical trial of beta-blocker therapy (atenolol) versus angiotensin II receptor blocker therapy (losartan) in individuals with Marfan syndromeNAC and DTT promote TGF-beta1 monomer formation: demonstration of competitive binding.Inhibition of autoregulated TGFbeta signaling simultaneously enhances proliferation and differentiation of kidney epithelium and promotes repair following renal ischemia.Future research directions in idiopathic pulmonary fibrosis: summary of a National Heart, Lung, and Blood Institute working group.Cytokine-regulated urokinase-type-plasminogen-activator (uPA) production by human breast fibroblasts in vitro.Highly sensitive and specific bioassay for measuring bioactive TGF-betaThrombospondin-2 therapy ameliorates experimental glomerulonephritis via inhibition of cell proliferation, inflammation, and TGF-beta activation.Development of a three dimensional multiscale computational model of the human epidermis.Modulatory proteins and processes in alliance with immune cells, mediators, and extracellular proteins in renal interstitial fibrosis.TGF-β activation and function in immunity.Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.The Good the Bad and the Ugly of Glycosaminoglycans in Tissue Engineering ApplicationsRegulating the availability of transforming growth factor ß1 in B104 neuroblastoma cellsRole of TGF-beta in immune-evasion of cancer.Role of transforming growth factor-beta1 in prostate cancer.Anticancer activity of VDR-coregulator inhibitor PS121912.Differential trafficking of transforming growth factor-beta receptors and ligand in polarized epithelial cells
P2860
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P2860
Latent transforming growth factor-beta: structural features and mechanisms of activation
description
1997 nî lūn-bûn
@nan
1997 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Latent transforming growth factor-beta: structural features and mechanisms of activation
@ast
Latent transforming growth factor-beta: structural features and mechanisms of activation
@en
Latent transforming growth factor-beta: structural features and mechanisms of activation
@nl
type
label
Latent transforming growth factor-beta: structural features and mechanisms of activation
@ast
Latent transforming growth factor-beta: structural features and mechanisms of activation
@en
Latent transforming growth factor-beta: structural features and mechanisms of activation
@nl
prefLabel
Latent transforming growth factor-beta: structural features and mechanisms of activation
@ast
Latent transforming growth factor-beta: structural features and mechanisms of activation
@en
Latent transforming growth factor-beta: structural features and mechanisms of activation
@nl
P2093
P3181
P356
P1433
P1476
Latent transforming growth factor-beta: structural features and mechanisms of activation
@en
P2093
P2888
P304
P3181
P356
10.1038/KI.1997.188
P407
P577
1997-05-01T00:00:00Z
P6179
1017703347