Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche - sprookjes - yvandenbroek - TriplyDB

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

http://www.wikidata.org/entity/Q28239639

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Global microRNA characterization reveals that miR-103 is involved in IGF-1 stimulated mouse intestinal cell proliferation What does the concept of the stem cell niche really mean today?R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5 LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signaling Homeostasis and inflammation in the intestine Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease Heparin-binding EGF-like growth factor protects intestinal stem cells from injury in a rat model of necrotizing enterocolitis.Basic helix-loop-helix transcription factors and enteroendocrine cell differentiation Mature chief cells are cryptic progenitors for metaplasia in the stomach Mammary Development and Breast Cancer: A Wnt Perspective hPSC-derived lung and intestinal organoids as models of human fetal tissue Paneth cell α-defensins and enteric microbiota in health and disease Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer Stem Cells in the Intestine: Possible Roles in Pathogenesis of Irritable Bowel Syndrome Integration of Signaling Pathways with the Epigenetic Machinery in the Maintenance of Stem Cells The role of enterocyte defects in the pathogenesis of congenital diarrheal disorders Organoid Models of Human Gastrointestinal Development and Disease Lingual Epithelial Stem Cells and Organoid Culture of Them Precision medicine for cancer with next-generation functional diagnostics Modeling psychiatric disorders for developing effective treatments LGR4 and Its Role in Intestinal Protection and Energy Metabolism Mouse models of intestinal cancer Similar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistance Colorectal cancer models for novel drug discovery The many ways to make a luminal cell and a prostate cancer cell The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes Cancer Cell Line Panels Empower Genomics-Based Discovery of Precision Cancer Medicine Understanding the complexities of Salmonella-host crosstalk as revealed by in vivo model organisms Innate lymphoid cells in graft-versus-host disease The potential of mesenchymal stem cells in the management of radiation enteropathy Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract Wound repair: role of immune-epithelial interactions Whole-organ re-engineering: a regenerative medicine approach to digestive organ replacement Tissue communication in regenerative inflammatory signaling: lessons from the fly gut Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins

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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

http://www.wikidata.org/entity/Q28239639

description

2009 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի մայիսին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Nature

@fr

artículu científicu espublizáu en 2009

@ast

scientific article (publication date: 14 May 2009)

@en

vedecký článok (publikovaný 2009/05/14)

@sk

vědecký článek publikovaný v roce 2009

@cs

wetenschappelijk artikel (gepubliceerd op 2009/05/14)

@nl

наукова стаття, опублікована в травні 2009

@uk

مقالة علمية (نشرت في 14-5-2009)

@ar

name

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

@ast

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

@en

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

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type

label

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

@ast

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

@en

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

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prefLabel

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

@ast

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

@en

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

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Arie Abo

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Hans Clevers

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Hugo J Snippert

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Johan H van Es

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Marc van de Wetering

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Nick Barker

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Pekka Kujala

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Peter J Peters

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Toshiro Sato

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scholarly article

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10.1038/NATURE07935

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Marc van de Wetering

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