R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
about
Novel insights into the bovine polled phenotype and horn ontogenesis in BovidaeInteraction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondinControl of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in CancerIn a Class of Their Own - RXFP1 and RXFP2 are Unique Members of the LGR FamilyLGR4 and Its Role in Intestinal Protection and Energy MetabolismKeeping Wnt signalosome in check by vesicular trafficLGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea.The structural basis of R-spondin recognition by LGR5 and RNF43Structural basis for R-spondin recognition by LGR4/5/6 receptorsCrystal Structures of Lgr4 and Its Complex with R-Spondin1Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondinStructures of Wnt-Antagonist ZNRF3 and Its Complex with R-Spondin 1 and Implications for SignalingResearch progress in the radioprotective effect of the canonical Wnt pathwayThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsHuman intestinal tissue with adult stem cell properties derived from pluripotent stem cells.Single Lgr5- or Lgr6-expressing taste stem/progenitor cells generate taste bud cells ex vivo.Analysis of LGR4 receptor distribution in human and mouse tissuesDistribution of LGR5+ cells and associated implications during the early stage of gastric tumorigenesis.A rare human syndrome provides genetic evidence that WNT signaling is required for reprogramming of fibroblasts to induced pluripotent stem cellsR-spondin 3 regulates dorsoventral and anteroposterior patterning by antagonizing Wnt/β-catenin signaling in zebrafish embryos.Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis.Identification of candidate gonadal sex differentiation genes in the chicken embryo using RNA-seqPhenotypic and Molecular Alterations in the Mammary Tissue of R-Spondin1 Knock-Out Mice during Pregnancy.The R-spondin family of proteins: emerging regulators of WNT signaling.LGR5 is associated with tumor aggressiveness in papillary thyroid cancer.Exogenous R-Spondin1 Induces Precocious Telogen-to-Anagen Transition in Mouse Hair FolliclesLGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation.Reconstitution of R-spondin:LGR4:ZNRF3 adult stem cell growth factor signaling complexes with recombinant proteins produced in Escherichia coli.Leucine-rich repeat-containing G-protein coupled receptor 5/GPR49 activates G12/13-Rho GTPase pathwayLGR4 and its ligands, R-spondin 1 and R-spondin 3, regulate food intake in the hypothalamus of male ratsRegulation of the follistatin gene by RSPO-LGR4 signaling via activation of the WNT/β-catenin pathway in skeletal myogenesis.Cryptosporidium parvum infection attenuates the ex vivo propagation of murine intestinal enteroidsThe R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strengthSide population sorting separates subfractions of cycling and non-cycling intestinal stem cellsRSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.LGR4/GPR48 inactivation leads to aniridia-genitourinary anomalies-mental retardation syndrome defects.The Lgr5 transgene is expressed specifically in glycinergic amacrine cells in the mouse retina.Evidence of the Role of R-Spondin 1 and Its Receptor Lgr4 in the Transmission of Mechanical Stimuli to Biological Signals for Bone Formation.Wnt-signalling in the embryonic mammary gland.Structure and function of LGR5: an enigmatic G-protein coupled receptor marking stem cells.
P2860
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P248
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P2860
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@ast
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@en
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@en-gb
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@nl
type
label
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@ast
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@en
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@en-gb
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@nl
altLabel
R-Spondin Potentiates Wnt/β-Catenin Signaling through Orphan Receptors LGR4 and LGR5
@en
prefLabel
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@ast
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@en
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@en-gb
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@nl
P2093
P2860
P921
P3181
P1433
P1476
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
@en
P2093
Adrian Salathe
Andrea Isken
Bianka Grosshans
Christian N Parker
Gabriele Hintzen
Gregory Michaud
Heinz Ruffner
Huaixiang Hao
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0040976
P407
P577
2012-07-16T00:00:00Z