Evolutionary silencing of the human elastase I gene (ELA1)
about
PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L.Inactivity of recombinant ELA2B provides a new example of evolutionary elastase silencing in humansA genomic analysis of rat proteases and protease inhibitorsEarly pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complexAn endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2).Exdpf is a key regulator of exocrine pancreas development controlled by retinoic acid and ptf1a in zebrafish.Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells.BMP-7 Induces Adult Human Pancreatic Exocrine-to-Endocrine Conversion.Specificity of a Polyclonal Fecal Elastase ELISA for CELA3.Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes.Replacing the Promoter of the Murine Gene Encoding P-selectin with the Human Promoter Confers Human-like Basal and Inducible Expression in Mice.MIST1 and PTF1 Collaborate in Feed-forward Regulatory Loops that Maintain the Pancreatic Acinar Phenotype in Adult Mice.Genetic Analysis of Human Chymotrypsin-Like Elastases 3A and 3B (CELA3A and CELA3B) to Assess the Role of Complex Formation between Proelastases and Procarboxypeptidases in Chronic Pancreatitis.The role of PTF1-P48 in pancreatic acinar gene expression.Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2.Potential for Screening for Pancreatic Exocrine Insufficiency Using the Fecal Elastase-1 Test.The tissue-specific regulation of the carboxyl ester lipase gene in exocrine pancreas differs significantly between mouse and humanMultiple transcriptional mechanisms control Ptf1a levels during neural development including autoregulation by the PTF1-J complex.Determinants of chymotrypsin C cleavage specificity in the calcium-binding loop of human cationic trypsinogen.An Expanded Multi-Organ Disease Phenotype Associated with Mutations in YARS.Myc cooperates with β-catenin to drive gene expression in nephron progenitor cells.Detection of human elastase isoforms by the ScheBo Pancreatic Elastase 1 Test.Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment.
P2860
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P2860
Evolutionary silencing of the human elastase I gene (ELA1)
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Evolutionary silencing of the human elastase I gene (ELA1)
@ast
Evolutionary silencing of the human elastase I gene (ELA1)
@en
Evolutionary silencing of the human elastase I gene (ELA1)
@nl
type
label
Evolutionary silencing of the human elastase I gene (ELA1)
@ast
Evolutionary silencing of the human elastase I gene (ELA1)
@en
Evolutionary silencing of the human elastase I gene (ELA1)
@nl
prefLabel
Evolutionary silencing of the human elastase I gene (ELA1)
@ast
Evolutionary silencing of the human elastase I gene (ELA1)
@en
Evolutionary silencing of the human elastase I gene (ELA1)
@nl
P2860
P3181
P356
P1476
Evolutionary silencing of the human elastase I gene (ELA1)
@en
P2093
R J MacDonald
P2860
P304
P3181
P356
10.1093/HMG/6.6.897
P407
P577
1997-06-01T00:00:00Z