Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells. - sprookjes - yvandenbroek - TriplyDB

Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells.

Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells.

http://www.wikidata.org/entity/Q33987709

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Control of cell identity in pancreas development and regeneration Silencing Mist1 Gene Expression Is Essential for Recovery from Acute Pancreatitis Transcription factor regulation of pancreatic organogenesis, differentiation and maturation MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer Directed pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factors Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis RNA profiling and chromatin immunoprecipitation-sequencing reveal that PTF1a stabilizes pancreas progenitor identity via the control of MNX1/HLXB9 and a network of other transcription factors LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function.Activation of postnatal neural stem cells requires nuclear receptor TLX Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells.The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma Deconstructing pancreas developmental biology.Hypoxia-inducible factor-2α stabilizes the von Hippel-Lindau (VHL) disease suppressor, Myb-related protein 2 Early pancreatic islet fate and maturation is controlled through RBP-Jκ Program specificity for Ptf1a in pancreas versus neural tube development correlates with distinct collaborating cofactors and chromatin accessibility.MIST1 and PTF1 Collaborate in Feed-forward Regulatory Loops that Maintain the Pancreatic Acinar Phenotype in Adult Mice.Icaritin enhances mESC self-renewal through upregulating core pluripotency transcription factors mediated by ERα.Lineage determinants in early endocrine development.Exocrine ontogenies: on the development of pancreatic acinar, ductal and centroacinar cells Sox9 and programming of liver and pancreatic progenitors.Notch signaling in the pancreas: patterning and cell fate specification.Transcriptional control of mammalian pancreas organogenesis.The acinar regulator Gata6 suppresses KrasG12V-driven pancreatic tumorigenesis in mice.Acinar cell plasticity and development of pancreatic ductal adenocarcinoma.The E3 ubiquitin ligase thyroid hormone receptor-interacting protein 12 targets pancreas transcription factor 1a for proteasomal degradation.Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation.Differentiation and Inflammation: 'Best Enemies' in Gastrointestinal Carcinogenesis.GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer.Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A.Activating transcription factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice.ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours.Functional and association analysis of an Amerindian-derived population-specific p.(Thr280Met) variant in RBPJL, a component of the PTF1 complex.Cellular and molecular mechanisms coordinating pancreas development.

P2860

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P2860

Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells.

http://www.wikidata.org/entity/Q33987709

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Replacement of Rbpj with Rbpjl ...... on of pancreatic acinar cells.

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Replacement of Rbpj with Rbpjl ...... on of pancreatic acinar cells.

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type

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Replacement of Rbpj with Rbpjl ...... on of pancreatic acinar cells.

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Replacement of Rbpj with Rbpjl ...... on of pancreatic acinar cells.

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Replacement of Rbpj with Rbpjl ...... on of pancreatic acinar cells.

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J.GASTRO.2010.04.003

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Gastroenterology

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Replacement of Rbpj with Rbpjl ...... on of pancreatic acinar cells.

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P2093

Chengcheng Shen

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Galvin H Swift

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Hans-Peter Elsässer

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Raymond J MacDonald

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Toshihiko Masui

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Ward S Coats

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P2860

Mapping and quantifying mammalian transcriptomes by RNA-Seq

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

Mutations in PTF1A cause pancreatic and cerebellar agenesis

PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L.

The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

BLAT--the BLAST-like alignment tool

The GOLD domain, a novel protein module involved in Golgi function and secretion

Genomic organisation, alternative splicing and primary structure of human matrilin-4

Transcription factors in liver development, differentiation, and regeneration

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1

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2902682

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