The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts
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MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damageMUC1-C oncoprotein activates ERK→C/EBPβ signaling and induction of aldehyde dehydrogenase 1A1 in breast cancer cellsMembrane-bound mucins: the mechanistic basis for alterations in the growth and survival of cancer cellsMicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1Novel agents for advanced pancreatic cancerMUC1 Predicts Colorectal Cancer Metastasis: A Systematic Review and Meta-Analysis of Case Controlled StudiesReactive oxygen species mediate Cr(VI)-induced carcinogenesis through PI3K/AKT-dependent activation of GSK-3β/β-catenin signalingMUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cellsMUC1 mucin interacts with calcium-modulating cyclophilin ligand.MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patientsMucin 1 gene (MUC1) and gastric-cancer susceptibilityInflammation driven by overexpression of the hypoglycosylated abnormal mucin 1 (MUC1) links inflammatory bowel disease and pancreatitis.Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.MUC1: a multifaceted oncoprotein with a key role in cancer progression.The cytoplasmic domain of MUC1 induces hyperplasia in the mammary gland and correlates with nuclear accumulation of β-catenin.MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasionIntrinsic mitochondrial membrane potential and associated tumor phenotype are independent of MUC1 over-expression.MUC1-C Oncoprotein Interacts Directly with ATM and Promotes the DNA Damage Response to Ionizing Radiation.MUC1c regulates cell survival in pancreatic cancer by preventing lysosomal permeabilization.The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loopTargeting the oncogenic MUC1-C protein inhibits mutant EGFR-mediated signaling and survival in non-small cell lung cancer cellsMUC1 oncoprotein suppresses activation of the ARF-MDM2-p53 pathwayMUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancerMUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cellsDependence on the MUC1-C oncoprotein in non-small cell lung cancer cells.MUC1 alters oncogenic events and transcription in human breast cancer cells.Emerging potential of natural products for targeting mucins for therapy against inflammation and cancer.Autophagy is decreased in triple-negative breast carcinoma involving likely the MUC1-EGFR-NEU1 signalling pathway.MUC1 cell surface mucin is a critical element of the mucosal barrier to infection.MUC1-C activates the TAK1 inflammatory pathway in colon cancerMUC1-C oncoprotein confers androgen-independent growth of human prostate cancer cells.Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein.Porphyromonas gingivalis-epithelial cell interactions in periodontitis.Inhibition of the MUC1-C oncoprotein is synergistic with cytotoxic agents in the treatment of breast cancer cells.The combined treatment with novel platinum(II) complex and anti-MUC1 increases apoptotic response in MDA-MB-231 breast cancer cells.Contextualizing the Genes Altered in Bladder Neoplasms in Pediatric andTeen Patients Allows Identifying Two Main Classes of Biological ProcessesInvolved and New Potential Therapeutic TargetsMUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches.MUC1-C Stabilizes MCL-1 in the Oxidative Stress Response of Triple-Negative Breast Cancer Cells to BCL-2 Inhibitors.Chemoresistance is associated with MUC1 and Lewis y antigen expression in ovarian epithelial cancers.Oncogenic MUC1-C promotes tamoxifen resistance in human breast cancer.
P2860
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P2860
The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts
description
2004 nî lūn-bûn
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2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The MUC1 oncoprotein activates ...... athways in rat 3Y1 fibroblasts
@ast
The MUC1 oncoprotein activates ...... athways in rat 3Y1 fibroblasts
@en
The MUC1 oncoprotein activates ...... athways in rat 3Y1 fibroblasts
@nl
type
label
The MUC1 oncoprotein activates ...... athways in rat 3Y1 fibroblasts
@ast
The MUC1 oncoprotein activates ...... athways in rat 3Y1 fibroblasts
@en
The MUC1 oncoprotein activates ...... athways in rat 3Y1 fibroblasts
@nl
prefLabel
The MUC1 oncoprotein activates ...... athways in rat 3Y1 fibroblasts
@ast
The MUC1 oncoprotein activates ...... athways in rat 3Y1 fibroblasts
@en
The MUC1 oncoprotein activates ...... athways in rat 3Y1 fibroblasts
@nl
P2093
P3181
P356
P1476
The MUC1 oncoprotein activates ...... athways in rat 3Y1 fibroblasts
@en
P2093
Deepak Raina
Donald Kufe
Surender Kharbanda
P304
P3181
P356
10.1074/JBC.M310538200
P407
P577
2004-05-14T00:00:00Z