Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.
about
MUC1 and MUC4: switching the emphasis from large to smallCharacterization of the MUC1-C Cytoplasmic Domain as a Cancer TargetEGFR-mediated carcinoma cell metastasis mediated by integrin αvβ5 depends on activation of c-Src and cleavage of MUC1.Apigenin Inhibits Tumor Necrosis Factor-α-Induced Production and Gene Expression of Mucin through Regulating Nuclear Factor-Kappa B Signaling Pathway in Airway Epithelial CellsMolecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets.Targeting the intracellular MUC1 C-terminal domain inhibits proliferation and estrogen receptor transcriptional activity in lung adenocarcinoma cells.Multivalent aptamer/gold nanoparticle-modified graphene oxide for mass spectrometry-based tumor tissue imagingTransmembrane mucins as novel therapeutic targetsEmerging potential of natural products for targeting mucins for therapy against inflammation and cancer.A monoclonal antibody against the oncogenic mucin 1 cytoplasmic domainMUC1-C oncoprotein confers androgen-independent growth of human prostate cancer cells.Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein.Inhibition of the MUC1-C oncoprotein is synergistic with cytotoxic agents in the treatment of breast cancer cells.The combined treatment with novel platinum(II) complex and anti-MUC1 increases apoptotic response in MDA-MB-231 breast cancer cells.MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches.Oncogenic MUC1-C promotes tamoxifen resistance in human breast cancer.Apigenin and Wogonin Regulate Epidermal Growth Factor Receptor Signaling Pathway Involved in MUC5AC Mucin Gene Expression and Production from Cultured Airway Epithelial Cells.The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma.Bone marrow stroma protects myeloma cells from cytotoxic damage via induction of the oncoprotein MUC1.MUC1 in hematological malignancies.Inhibition of TNF-α-induced MUC5AC mucin gene expression and production by wogonin through the inactivation of NF-κB signaling in airway epithelial cells.Phorbol ester or epidermal growth-factor-induced MUC5AC mucin gene expression and production from airway epithelial cells are inhibited by apigenin and wogonin.Muc1/Cd227 immunohistochemistry in routine practice is a useful biomarker in breast cancers.Apigenin overcomes drug resistance by blocking the signal transducer and activator of transcription 3 signaling in breast cancer cells.Implication of Soluble Forms of Cell Adhesion Molecules in Infectious Disease and Tumor: Insights from Transgenic Animal Models.Polyubiquitination inhibition of estrogen receptor alpha and its implications in breast cancer
P2860
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P2860
Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.
@ast
Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.
@en
type
label
Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.
@ast
Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.
@en
prefLabel
Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.
@ast
Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.
@en
P2093
P2860
P356
P1476
Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.
@en
P2093
Donald Kufe
Hasan Rajabi
Yongchun Zhou
P2860
P304
P356
10.1124/MOL.110.070797
P577
2011-02-23T00:00:00Z