IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus
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Dysregulation of antiviral helicase pathways in systemic lupus erythematosusNucleic Acid sensors and type I interferon production in systemic lupus erythematosusGenetic Factors in Systemic Lupus Erythematosus: Contribution to Disease PhenotypeRole of type I interferons in the activation of autoreactive B cellsUnmet medical needs in systemic lupus erythematosusAdvances in lupus geneticsEmerging therapies for systemic lupus erythematosus--focus on targeting interferon-alphaBrief Report: IRF5 systemic lupus erythematosus risk haplotype is associated with asymptomatic serologic autoimmunity and progression to clinical autoimmunity in mothers of children with neonatal lupusThe pathogenesis of systemic lupus erythematosus—an updateBlood gene expression profiling in pediatric systemic lupus erythematosus and systemic juvenile idiopathic arthritis: from bench to bedside.Genetics of ancestry-specific risk for relapse in acute lymphoblastic leukemiaAdvances in lupus genetics and epigeneticsThe systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis.The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably shareInterferon regulatory factors: critical mediators of human lupus.TRIpartite motif 21 (TRIM21) differentially regulates the stability of interferon regulatory factor 5 (IRF5) isoforms.Much More than M1 and M2 Macrophages, There are also CD169(+) and TCR(+) Macrophages.Animal Models of Interferon Signature Positive Lupus.Role of cytokines in systemic lupus erythematosus: recent progress from GWAS and sequencing.Gene-expression-guided selection of candidate loci and molecular phenotype analyses enhance genetic discovery in systemic lupus erythematosus.Immunogenetics of systemic lupus erythematosus: A comprehensive review.The type I interferons: Basic concepts and clinical relevance in immune-mediated inflammatory diseases.TRAF1 gene polymorphism correlates with the titre of Gp210 antibody in patients with primary biliary cirrhosis.Monogenic forms of systemic lupus erythematosus: new insights into SLE pathogenesisIRF5 gene polymorphisms in melanomaGenetics of SLE: functional relevance for monocytes/macrophages in diseasePleiotropic IFN-dependent and -independent effects of IRF5 on the pathogenesis of experimental lupusGenome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.Activation of the Interferon Pathway is Dependent Upon Autoantibodies in African-American SLE Patients, but Not in European-American SLE Patients.Familial aggregation of high tumor necrosis factor alpha levels in systemic lupus erythematosus.Genetic variation near IRF8 is associated with serologic and cytokine profiles in systemic lupus erythematosus and multiple sclerosis.Genetics of the type I interferon pathway in systemic lupus erythematosus.Functional genetic polymorphisms in ILT3 are associated with decreased surface expression on dendritic cells and increased serum cytokines in lupus patientsPresence of an interferon signature in individuals who are anti-nuclear antibody positive lacking a systemic autoimmune rheumatic disease diagnosis.Interferon regulatory factor 5 in the pathogenesis of systemic lupus erythematosus.Interferon regulatory factor 5 and autoimmune lupus.Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis.Identification of three new cis-regulatory IRF5 polymorphisms: in vitro studies.IRF5 risk polymorphisms contribute to interindividual variance in pattern recognition receptor-mediated cytokine secretion in human monocyte-derived cells.Autoimmune disease genetics 2013
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P2860
IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
IRF5 haplotypes demonstrate di ...... h systemic lupus erythematosus
@ast
IRF5 haplotypes demonstrate di ...... h systemic lupus erythematosus
@en
IRF5 haplotypes demonstrate di ...... h systemic lupus erythematosus
@nl
type
label
IRF5 haplotypes demonstrate di ...... h systemic lupus erythematosus
@ast
IRF5 haplotypes demonstrate di ...... h systemic lupus erythematosus
@en
IRF5 haplotypes demonstrate di ...... h systemic lupus erythematosus
@nl
prefLabel
IRF5 haplotypes demonstrate di ...... h systemic lupus erythematosus
@ast
IRF5 haplotypes demonstrate di ...... h systemic lupus erythematosus
@en
IRF5 haplotypes demonstrate di ...... h systemic lupus erythematosus
@nl
P2093
P2860
P50
P1476
IRF5 haplotypes demonstrate di ...... h systemic lupus erythematosus
@en
P2093
Akaash A Kumar
Beverly S Franek
Daniel Walker
Diane L Kamen
Gary S Gilkeson
Graciela S Alarcón
Jeffrey C Edberg
Joan T Merrill
Kathy L Moser
Kenaz Thomas
P2860
P356
10.1136/ANNRHEUMDIS-2011-200463
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P50
P577
2012-03-01T00:00:00Z