Defining the specificity space of the human SRC homology 2 domain - sprookjes - yvandenbroek - TriplyDB

Defining the specificity space of the human SRC homology 2 domain

Defining the specificity space of the human SRC homology 2 domain

http://www.wikidata.org/entity/Q28254456

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The conservation pattern of short linear motifs is highly correlated with the function of interacting protein domains SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells.Phospho-tyrosine dependent protein-protein interaction network The development and application of a quantitative peptide microarray based approach to protein interaction domain specificity space An evolutionary perspective on the kinome of malaria parasites Short linear motifs - ex nihilo evolution of protein regulation Structural Basis for c-KIT Inhibition by the Suppressor of Cytokine Signaling 6 (SOCS6) Ubiquitin Ligase Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism Two Closely Spaced Tyrosines Regulate NFAT Signaling in B Cells via Syk Association with Vav Simultaneous Binding of Two Peptidyl Ligands by a Src Homology 2 Domain Differential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domain Superbinder SH2 domains act as antagonists of cell signaling Two Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase Src Homology 2 Domains for Phosphorylated Cortactin Structural basis for a novel interaction between TXNIP and Vav2 High-throughput analysis of peptide-binding modules Phosphotyrosine signaling proteins that drive oncogenesis tend to be highly interconnected A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases SH2 Domains Recognize Contextual Peptide Sequence Information to Determine Selectivity Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide.T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells.Iterative tyrosine phosphorylation controls non-canonical domain utilization in Crk.SH3 interactome conserves general function over specific form.Domain-mediated protein interaction prediction: From genome to network.The identification of short linear motif-mediated interfaces within the human interactome Src tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer.Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain.An adaptor role for cytoplasmic Sam68 in modulating Src activity during cell polarization.Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.Exploring the pathogenetic association between schizophrenia and type 2 diabetes mellitus diseases based on pathway analysis.Dynamic steps in receptor tyrosine kinase mediated activation of class IA phosphoinositide 3-kinases (PI3K) captured by H/D exchange (HDX-MS).Prediction of phosphotyrosine signaling networks using a scoring matrix-assisted ligand identification approach.On-bead screening of combinatorial libraries: reduction of nonspecific binding by decreasing surface ligand density.Generating a panel of highly specific antibodies to 20 human SH2 domains by phage display A regression framework incorporating quantitative and negative interaction data improves quantitative prediction of PDZ domain-peptide interaction from primary sequence.Mapping protein interactions by combining antibody affinity maturation and mass spectrometry.

P2860

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P2860

Defining the specificity space of the human SRC homology 2 domain

http://www.wikidata.org/entity/Q28254456

description

2008 nî lūn-bûn

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2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2008 թվականի ապրիլին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Defining the specificity space of the human SRC homology 2 domain

@ast

Defining the specificity space of the human SRC homology 2 domain

@en

Defining the specificity space of the human SRC homology 2 domain

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type

label

Defining the specificity space of the human SRC homology 2 domain

@ast

Defining the specificity space of the human SRC homology 2 domain

@en

Defining the specificity space of the human SRC homology 2 domain

@nl

prefLabel

Defining the specificity space of the human SRC homology 2 domain

@ast

Defining the specificity space of the human SRC homology 2 domain

@en

Defining the specificity space of the human SRC homology 2 domain

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MCP.M700312-MCP200

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Molecular & Cellular Proteomics

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Defining the specificity space of the human SRC homology 2 domain

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P2093

Chenggang Wu

http://www.w3.org/2001/XMLSchema#string

Chengjun Li

http://www.w3.org/2001/XMLSchema#string

David Schibli

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Haiming Huang

http://www.w3.org/2001/XMLSchema#string

Krystina Ho

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Lei Li

http://www.w3.org/2001/XMLSchema#string

Protiva Roy

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Shawn S-C Li

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Sucan Ma

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Youhe Gao

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P2860

Unequal evolutionary conservation of human protein interactions in interologous networks

The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

Molecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinase

Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome

A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome

The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export

Structural bases of unphosphorylated STAT1 association and receptor binding

Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide

The protein kinase complement of the human genome

Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

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768-84

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496898

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10.1074/MCP.M700312-MCP200

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