Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer - sprookjes - yvandenbroek - TriplyDB

Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

http://www.wikidata.org/entity/Q28264693

about

Regulation and function of the human HSP90AA1 gene Multiscale integration of -omic, imaging, and clinical data in biomedical informatics.A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype.Upregulation of heat shock factor 1 transcription activity is associated with hepatocellular carcinoma progression.Immunologic targeting of FOXP3 in inflammatory breast cancer cells.Trianthema portulacastrum Linn. displays anti-inflammatory responses during chemically induced rat mammary tumorigenesis through simultaneous and differential regulation of NF-κB and Nrf2 signaling pathways.Identification of estrogen receptor proteins in breast cancer cells using matrix-assisted laser desorption/ionization time of flight mass spectrometry (Review).Proteomics profiling identify CAPS as a potential predictive marker of tamoxifen resistance in estrogen receptor positive breast cancer.Novel insights into embryonic stem cell self-renewal revealed through comparative human and mouse systems biology networks Overexpression of the EMT driver brachyury in breast carcinomas: association with poor prognosis.Personalized medicine and pharmacogenetic biomarkers: progress in molecular oncology testing.Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease.Stress Inducibility of SIRT1 and Its Role in Cytoprotection and Cancer.Hsp90, an unlikely ally in the war on cancer.Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells.Heat shock protein 70-2 (HSP70-2) overexpression in breast cancer Suppression of inflammatory cascade is implicated in methyl amooranin-mediated inhibition of experimental mammary carcinogenesis.Identification of Genetic and Epigenetic Variants Associated with Breast Cancer Prognosis by Integrative Bioinformatics Analysis.Testing breast cancer serum biomarkers for early detection and prognosis in pre-diagnosis samples.Validation of a network-based strategy for the optimization of combinatorial target selection in breast cancer therapy: siRNA knockdown of network targets in MDA-MB-231 cells as an in vitro model for inhibition of tumor development.An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models.Prospective identification of resistance mechanisms to HSP90 inhibition in KRAS mutant cancer cells.A novel integrative risk index of papillary thyroid cancer progression combining genomic alterations and clinical factors.Integrated Proteomic and Transcriptomic-Based Approaches to Identifying Signature Biomarkers and Pathways for Elucidation of Daoy and UW228 Subtypes.The significance of heat shock proteins in breast cancer therapy.Combined inhibition of heat shock proteins 90 and 70 leads to simultaneous degradation of the oncogenic signaling proteins involved in muscle invasive bladder cancer.HSP90AB1: Helping the good and the bad.Grating coupled SPR microarray analysis of proteins and cells in blood from mice with breast cancer.Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models.Functional proteomics outlines the complexity of breast cancer molecular subtypes.Geldanamycin-mediated inhibition of heat shock protein 90 partially activates dendritic cells, but interferes with their full maturation, accompanied by impaired upregulation of RelB.The 8th international symposium on the breast: Using next-generation science to understand the normal breast and the development of breast cancer- conference report.Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens.The overexpression of Hsp90B1 is associated with tumorigenesis of canine mammary glands.Fragment-based in silico modeling of multi-target inhibitors against breast cancer-related proteins.Identification and quantification of novel RNA isoforms in horn cancer of Bos indicus by comprehensive RNA-Seq.Analysis of HSP90 Expression Is Valuable in the Differential Diagnosis of Ocular Surface Squamous Lesions.Intrinsic proteotoxic stress levels vary and act as a predictive marker for sensitivity of cancer cells to Hsp90 inhibition HSP90AA1-mediated autophagy promotes drug resistance in osteosarcoma Anticancer effects of plant derived Anacardic acid on human breast cancer MDA-MB-231 cells

P2860

Q28646043-BF7DC00D-AF00-4C41-B733-ED80577B5E42 Q30581136-8C54FF5D-7958-482D-B2D7-C9378B309EDC Q34296481-0BCF8264-29F3-4639-9072-58B97FE9BA64 Q34426830-690DFEE6-EE3F-4A59-A584-93A282208688 Q34558393-3A2FE7E0-39CA-44DD-BD28-1BBB5CC7221B Q35138880-DEED1323-33C2-44B7-A37D-FA131AADFD96 Q35157380-0355B2C4-4EC9-4A91-BC6B-31902EC5C24F Q35313220-03475B96-A140-4E8C-89D0-B46048C2BF52 Q35500571-0F2E7E1B-5DAD-4859-8C57-524631EAE2FE Q36057732-BCBB7BBD-1530-4CC9-AB70-BEA82542C6C2 Q36392598-5EF3FBE6-796D-42EF-86AF-A7D86076DE1E Q37068669-CEAB0280-EE55-49A6-9E62-654597906C83 Q37150530-585DCABC-1B24-4944-B702-668EA1C8B6C0 Q37274497-CD993460-A785-4E43-9A26-378F2FB61AEC Q37274516-C4B550B3-77D1-441F-8181-DD69A2D74B8D Q37278498-A77AF4B8-29F9-4564-AAB6-CA280478374E Q37466405-928A681C-20A4-4DA7-9A64-AE4F8BD7187B Q37577093-3AEF57F0-40A2-40B6-A1B4-095A99F58AF6 Q37655098-C56C718A-DA48-47FB-A7E7-DFA6B09AE320 Q37665293-13D5A001-585E-4DA2-85AD-616BD2CC14BB Q37690880-B54326EB-9861-4D56-AC11-2ED2C0C20054 Q37702589-43AB79BE-2E6E-47CD-9F09-4158CA17A6DC Q37725502-6EC164F6-92AE-4946-8F1E-0B8E42B523A9 Q37728564-001B7E6C-4B86-4A8C-A4A3-E1586200836F Q38100745-72056C46-E1A7-426D-9377-61215194001B Q38261693-35021E3B-1A0D-4FE2-A472-8F9D94C45B5C Q38584468-AD3F2FBE-B485-4319-9330-37C6C8BFEEDC Q38821891-1A55449B-95D9-4666-BAEB-EE8442D83307 Q38966874-FCEB3B98-B924-420B-BA74-9E0AF4EB1C04 Q41564586-1013F5A2-C4F5-4144-A780-FEF0BADD9C86 Q41959409-994EBF62-6836-4E3D-ADB5-5A49270ABA5B Q46647592-4D4637F6-2FFB-4A16-8301-BDC403C69B7E Q47135858-6F71A486-5348-4446-9DBA-23BE9A178D7B Q47962055-8E731A37-5C6F-465D-B6F0-DF354A0D026D Q48242157-9BA5BB26-2223-41FF-BD11-1806D301E865 Q53348019-C409AB62-B46D-4195-A079-7D423789F3ED Q54117138-C0741CCB-D145-4412-8496-359E82E78C04 Q57167862-EA55FF07-217B-4F6B-B34B-DE075FB3263B Q58698951-06627DAC-A0F1-42AE-B51F-11627142CA88 Q58775975-8518B517-C7C4-471E-AD5D-9A1EE3B5F239

P2860

Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

http://www.wikidata.org/entity/Q28264693

description

2012 nî lūn-bûn

@nan

2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Amplification and high-level e ...... eptor 2 negative breast cancer

@ast

Amplification and high-level e ...... eptor 2 negative breast cancer

@en

Amplification and high-level e ...... eptor 2 negative breast cancer

@nl

type

label

Amplification and high-level e ...... eptor 2 negative breast cancer

@ast

Amplification and high-level e ...... eptor 2 negative breast cancer

@en

Amplification and high-level e ...... eptor 2 negative breast cancer

@nl

prefLabel

Amplification and high-level e ...... eptor 2 negative breast cancer

@ast

Amplification and high-level e ...... eptor 2 negative breast cancer

@en

Amplification and high-level e ...... eptor 2 negative breast cancer

@nl

P1433

Q28264693-AC62A254-9B83-490D-8AC4-DEECB4113F05

P1476

Q28264693-2891320F-1E89-476C-B2D5-7EBDAED99756

P2093

Q28264693-271EDCFB-0C54-4DA5-846C-B63206336E75

Q28264693-3CBA3FF7-D788-49F6-98E1-ED7CDF2DC225

Q28264693-65B63595-44BE-4842-BBDB-2E2543B13698

Q28264693-BFAB183A-D5EB-4E4D-A45B-9749E913616C

Q28264693-D4B296AD-B3D5-4524-95BB-453392137CB0

Q28264693-D9C37AF3-554C-45E1-98EC-02068E943CB3

P2860

Q28264693-0058E97E-CD5F-484E-8EEB-61A989869FF2

Q28264693-06D0367E-889E-4A89-80FF-622AB680B6FB

Q28264693-0BC0673B-8843-4953-9608-4E1279978EC1

Q28264693-0F9CEAC9-826D-443D-ACCA-2BFD93A027C9

Q28264693-13DA25CC-2005-4056-8A9E-E4BCF5761FAC

Q28264693-1458E884-7FF9-4535-919E-976094522842

Q28264693-154605C4-8622-4283-8311-B0AAF3448E57

Q28264693-1CA0D65F-6DD4-4540-948C-5646E2BE2622

Q28264693-21AA7789-9584-4627-B6F0-DB398CC4DF56

Q28264693-24ECC6BB-5DA6-4976-8671-224DEB5B5845

P2888

Q28264693-5A971CD2-4518-4254-A7B5-A5FF331B4711

P304

Q28264693-BC7EBABC-81C5-4E30-BFDE-E6E47FF4B9E9

P31

Q28264693-297EE8CF-518C-46C4-A033-E0BBF51BA2AD

P3181

Q28264693-39CE7373-0240-4541-962E-6AB0789D79E7

P356

Q28264693-4C927577-5D1A-49AF-9E86-689CFACDB228

P407

Q28264693-7665BC40-A44A-480A-B8D2-0F80A87C2999

P433

Q28264693-9288B094-4586-47CB-87F1-D101F4D050E8

P478

Q28264693-5F4A7317-972E-44C3-A3FE-32AB8E51F79D

P50

Q28264693-C9A17862-97A0-49C3-B173-EB52F6C8A2EE

P577

Q28264693-70BD4E9B-65F0-42D7-8B6B-CF1D76BE5C90

P5875

Q28264693-DA50367C-36C6-4001-8A2E-CA2F0A9E54B6

P6179

Q28264693-C02BEA85-4C76-480A-AF18-B3EFB3EF7A12

P698

Q28264693-FBC460F5-65F9-4CBB-B30C-CC3A3372C685

P932

Q28264693-1B0402EA-8C2B-4E88-AE2D-D3A3E9346B20

P3181

P356

P1433

Breast Cancer Research

P1476

Amplification and high-level e ...... eptor 2 negative breast cancer

@en

P2093

Jeffrey T Chang

http://www.w3.org/2001/XMLSchema#string

Joseph Geradts

http://www.w3.org/2001/XMLSchema#string

Leonard M Neckers

http://www.w3.org/2001/XMLSchema#string

Neil L Spector

http://www.w3.org/2001/XMLSchema#string

Qing Cheng

http://www.w3.org/2001/XMLSchema#string

Timothy Haystead

http://www.w3.org/2001/XMLSchema#string

P2860

Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway

Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis

Genes that mediate breast cancer metastasis to the brain

Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer

Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts.

Application of chemoproteomics to drug discovery: identification of a clinical candidate targeting hsp90

Cancer statistics, 2010

Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90

Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells

Integration of gene dosage and gene expression in non-small cell lung cancer, identification of HSP90 as potential target

P2888

P304

R62

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3400225

http://www.w3.org/2001/XMLSchema#string

P356

10.1186/BCR3168

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

14

http://www.w3.org/2001/XMLSchema#string

P50

Herbert Kim Lyerly

P577

2012-04-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

224283860

http://www.w3.org/2001/XMLSchema#string

P6179

1003748055

http://www.w3.org/2001/XMLSchema#string

P698

22510516

http://www.w3.org/2001/XMLSchema#string

P932

3446397

http://www.w3.org/2001/XMLSchema#string