Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA - sprookjes - yvandenbroek - TriplyDB

Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA

Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA

http://www.wikidata.org/entity/Q28267082

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Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C Negative regulation of Rho family GTPases Cdc42 and Rac2 by homodimer formation A molecular model for axon guidance based on cross talk between rho GTPases.Design of versatile biochemical switches that respond to amplitude, duration, and spatial cues Rho GTPases: Novel Players in the Regulation of the DNA Damage Response?Modulation of osteoclast differentiation and bone resorption by Rho GTPases The Salmonella SPI2 effector SseI mediates long-term systemic infection by modulating host cell migration Rational stabilization of enzymes by computational redesign of surface charge-charge interactions The Structure of the RLIP76 RhoGAP-Ral Binding Domain Dyad: Fixed Position of the Domains Leads to Dual Engagement of Small G Proteins at the Membrane Functional characterization of the Bag7, Lrg1 and Rgd2 RhoGAP proteins from Saccharomyces cerevisiae.Simulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilin The PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1 The function of the p190 Rho GTPase-activating protein is controlled by its N-terminal GTP binding domain Rho GTPases and their effector proteins p63RhoGEF couples Gα(q/11)-mediated signaling to Ca2+ sensitization of vascular smooth muscle contractility.Regulation of cytokinesis by Rho GTPase flux.ERK and phosphoinositide 3-kinase temporally coordinate different modes of actin-based motility during embryonic wound healing.Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP.Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1.Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma Predicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway.Hematopoietic-specific Rho GTPases Rac2 and RhoH and human blood disorders.Identification of Transcriptional Modules and Key Genes in Chickens Infected with Salmonella enterica Serovar Pullorum Using Integrated Coexpression Analyses IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES.Leucine-rich repeat kinase 2 (LRRK2)/PARK8 possesses GTPase activity that is altered in familial Parkinson's disease R1441C/G mutants.Rac1 protein signaling is required for DNA damage response stimulated by topoisomerase II poisons.Caspase 3-mediated inactivation of rac GTPases promotes drug-induced apoptosis in human lymphoma cells.A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells.Localization of the PAK1-, WASP-, and IQGAP1-specifying regions of Cdc42.RHO GTPase Effectors RHO GTPases activate PAKs Arabidopsis RopGAPs are a novel family of rho GTPase-activating proteins that require the Cdc42/Rac-interactive binding motif for rop-specific GTPase stimulation.Drosophila Syd-1 Has RhoGAP Activity That Is Required for Presynaptic Clustering of Bruchpilot/ELKS but Not Neurexin-1.The IQGAP1-Rac1 and IQGAP1-Cdc42 interactions: interfaces differ between the complexes.New model for the interaction of IQGAP1 with CDC42 and RAC1.Activation of PAKs by RAC1 and CDC42 RAC1 and CDC42 activate PAK2 RAC1 and CDC42 activate PAK3 Simulation of the regulation of EGFR endocytosis and EGFR-ERK signaling by endophilin-mediated RhoA-EGFR crosstalk.A built-in arginine finger triggers the self-stimulatory GTPase-activating activity of rho family GTPases.

P2860

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P2860

Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA

http://www.wikidata.org/entity/Q28267082

description

1998 nî lūn-bûn

@nan

1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի ապրիլին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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name

Interaction of Rac1 with GTPas ...... comparison with Cdc42 and RhoA

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Interaction of Rac1 with GTPas ...... comparison with Cdc42 and RhoA

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Interaction of Rac1 with GTPas ...... comparison with Cdc42 and RhoA

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label

Interaction of Rac1 with GTPas ...... comparison with Cdc42 and RhoA

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Interaction of Rac1 with GTPas ...... comparison with Cdc42 and RhoA

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Interaction of Rac1 with GTPas ...... comparison with Cdc42 and RhoA

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Interaction of Rac1 with GTPas ...... comparison with Cdc42 and RhoA

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Interaction of Rac1 with GTPas ...... comparison with Cdc42 and RhoA

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Interaction of Rac1 with GTPas ...... comparison with Cdc42 and RhoA

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JBC.273.15.8776

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Journal of Biological Chemistry

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Interaction of Rac1 with GTPas ...... comparison with Cdc42 and RhoA

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B Zhang

http://www.w3.org/2001/XMLSchema#string

Y Zheng

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P2860

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia

IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments

Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit

The structure of the GTPase-activating domain from p50rhoGAP

The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

Crystal structure of RhoA-GDP and its functional implications

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

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8776-82

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10.1074/JBC.273.15.8776

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15

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273

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Jonathan Chernoff

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51328185

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9535855

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