The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes
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Clinical Overview of MDM2/X-Targeted TherapiesHuman papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway.Soluble Egg Antigens of Schistosoma japonicum Induce Senescence of Activated Hepatic Stellate Cells by Activation of the FoxO3a/SKP2/P27 Pathway.Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks.Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex.MYBL2 (B-Myb): a central regulator of cell proliferation, cell survival and differentiation involved in tumorigenesis.Central spindle proteins and mitotic kinesins are direct transcriptional targets of MuvB, B-MYB and FOXM1 in breast cancer cell lines and are potential targets for therapyThe expanding role of the Ehmt2/G9a complex in neurodevelopment.An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma.P53 suppresses ribonucleotide reductase via inhibiting mTORC1.POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologiesCensus and evaluation of p53 target genes.p53 downregulates the Fanconi anaemia DNA repair pathway.The Transcriptional Landscape of p53 Signalling PathwayAkt/FoxM1 signaling pathway-mediated upregulation of MYBL2 promotes progression of human glioma.Identification of a p53-repressed gene module in breast cancer cells.2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G2/M cell cycle arrest through generation of thiol oxidative stress in human esophageal canceFledglings in p53 signaling network.p21 governs p53's repressive side.Mutation analysis and copy number alterations of KIF23 in non-small-cell lung cancer exhibiting KIF23 over-expression.Stopping cells from dividing.miR-422a inhibits cell proliferation in colorectal cancer by targeting AKT1 and MAPK1.Quercetrin from Toona sinensis leaves induces cell cycle arrest and apoptosis via enhancement of oxidative stress in human colorectal cancer SW620 cells.Timing of transcription during the cell cycle: Protein complexes binding to E2F, E2F/CLE, CDE/CHR, or CHR promoter elements define early and late cell cycle gene expression.Inhibition of coiled coil domain containing protein 69 enhances platinum-induced apoptosis in ovarian cancer cells.The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation.Loss of p53-inducible long non-coding RNA LINC01021 increases chemosensitivity.Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM.Mechanisms of transcriptional regulation by p53.SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression.Cell cycle transcription control: DREAM/MuvB and RB-E2F complexes.Target delivery of doxorubicin tethered with PVP stabilized gold nanoparticles for effective treatment of lung cancer.Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence.The Guardian of the Genome Revisited: p53 Downregulates Genes Required for Telomere Maintenance, DNA Repair, and Centromere Structure.TRIM32 promotes proliferation and confers chemoresistance to breast cancer cells through activation of the NF-κB pathway.MuvB: A Key to Cell Cycle Control in Ovarian Cancer.FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescenceRevealing a human p53 universeTBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets
P2860
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P2860
The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes
description
2016 nî lūn-bûn
@nan
2016 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes
@ast
The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes
@en
The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes
@nl
type
label
The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes
@ast
The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes
@en
The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes
@nl
prefLabel
The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes
@ast
The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes
@en
The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes
@nl
P2860
P3181
P356
P1476
The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes
@en
P2093
Lydia Steiner
Marianne Quaas
P2860
P304
P3181
P356
10.1093/NAR/GKV927
P407
P577
2016-01-08T00:00:00Z