Morphine and metabolite behavior after different routes of morphine administration: demonstration of the importance of the active metabolite morphine-6-glucuronide
about
The analgesic activity of morphine-6-glucuronide.Nephrectomized and hepatectomized animal models as tools in preclinical pharmacokineticsRole of active metabolites in the use of opioidsLack of effect of ondansetron on the pharmacokinetics and analgesic effects of morphine and metabolites after single-dose morphine administration in healthy volunteersPharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: comparisons between extensive and poor hydroxylators of debrisoquineAccidental subcutaneous remifentanil infusion as a cause of delayed awakening after craniotomyDevelopment of a Whole-Body Physiologically Based Pharmacokinetic Approach to Assess the Pharmacokinetics of Drugs in Elderly IndividualsThe effect of ethanol on oral cocaine pharmacokinetics reveals an unrecognized class of ethanol-mediated drug interactions.Pharmacokinetics of morphine infusion in premature neonates.The role of morphine glucuronides in cancer pain.The role of liquid chromatography-mass spectrometry in the determination of heroin and related opioids in biological fluids.Anesthetic medications in breastfeeding mothers.Pharmacokinetics of oral morphine sulfate in dogs: a comparison of sustained release and conventional formulations.Rationalization and prediction of in vivo metabolite exposures: the role of metabolite kinetics, clearance predictions and in vitro parameters.Morphine and morphine-glucuronide concentrations in plasma and CSF during long-term administration of oral morphineThe pharmacokinetics of oxycodone after intravenous injection in adults.Analgesic efficacy of controlled-release oxycodone in postoperative pain.The pharmacokinetics and metabolism of oxycodone after intramuscular and oral administration to healthy subjectsThe influence of renal function on the renal clearance of morphine and its glucuronide metabolites in intensive-care patients.Morphine glucuronidation in premature neonatesManagement of opioid-induced gastrointestinal effects in patients receiving palliative care.The panorama of opioid-related cognitive dysfunction in patients with cancer: a critical literature appraisal.Increased clearance of morphine in sickle cell disease: implications for pain management.Contribution of the human kidney to the metabolic clearance of drugs.The conversion challenge: from intrathecal to oral morphine.The bioavailability and pharmacokinetics of subcutaneous, nebulized and oral morphine-6-glucuronideBlood-brain barrier transport of morphine in patients with severe brain traumaAltered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitisMorphine and morphine-6-glucuronide in the plasma and cerebrospinal fluid of childrenThe pharmacokinetics of morphine and morphine glucuronide metabolites after subcutaneous bolus injection and subcutaneous infusion of morphine.Synthesis and characterization of a dual kappa-delta opioid receptor agonist analgesic blocking cocaine reward behaviorNeuroexcitatory effects of morphine-3-glucuronide are dependent on Toll-like receptor 4 signaling.Differences in absorption, distribution, metabolism and excretion of xenobiotics between the paediatric and adult populations.HIM-herbal ingredients in-vivo metabolism databaseMorphine-6-glucuronide (M6G) for postoperative pain relief.Characterization of Contributing Factors to Variability in Morphine Clearance Through PBPK Modeling Implemented With OCT1 Transporter.UDP-glucuronosyltransferases (UGTs) in neuro-olfactory tissues: expression, regulation, and function.In vitro and in vivo small intestinal metabolism of CYP3A and UGT substrates in preclinical animals species and humans: species differences.Morphine metabolism, transport and brain disposition.Comparison and analysis of the animal models used to study the effect of morphine on tumour growth and metastasis
P2860
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P2860
Morphine and metabolite behavior after different routes of morphine administration: demonstration of the importance of the active metabolite morphine-6-glucuronide
description
1990 nî lūn-bûn
@nan
1990 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Morphine and metabolite behavi ...... abolite morphine-6-glucuronide
@ast
Morphine and metabolite behavi ...... abolite morphine-6-glucuronide
@en
Morphine and metabolite behavi ...... abolite morphine-6-glucuronide
@nl
type
label
Morphine and metabolite behavi ...... abolite morphine-6-glucuronide
@ast
Morphine and metabolite behavi ...... abolite morphine-6-glucuronide
@en
Morphine and metabolite behavi ...... abolite morphine-6-glucuronide
@nl
prefLabel
Morphine and metabolite behavi ...... abolite morphine-6-glucuronide
@ast
Morphine and metabolite behavi ...... abolite morphine-6-glucuronide
@en
Morphine and metabolite behavi ...... abolite morphine-6-glucuronide
@nl
P2093
P3181
P356
P1476
Morphine and metabolite behavi ...... abolite morphine-6-glucuronide
@en
P2093
P2888
P3181
P356
10.1038/CLPT.1990.2
P407
P577
1990-01-01T00:00:00Z
P5875
P6179
1015687088