Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5'-O-(3-[35S]thio)triphosphate binding studies reflects binding of an endogenous agonist
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Potential roles of GPR120 and its agonists in the management of diabetesThe action and mode of binding of thiazolidinedione ligands at free fatty acid receptor 1Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsLipid receptors and islet function: therapeutic implications?The saturated fatty acid, palmitic acid, induces anxiety-like behavior in mice.Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator.Attenuation of inflammatory and neuropathic pain behaviors in mice through activation of free fatty acid receptor GPR40.Hunting for the function of orphan GPCRs - beyond the search for the endogenous ligand.G Protein-coupled Receptor 40 (GPR40) and Peroxisome Proliferator-activated Receptor γ (PPARγ): AN INTEGRATED TWO-RECEPTOR SIGNALING PATHWAY.Thiazolidinediones induce osteocyte apoptosis by a G protein-coupled receptor 40-dependent mechanism.Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptorTwo arginine-glutamate ionic locks near the extracellular surface of FFAR1 gate receptor activation.Progress in the discovery and development of small-molecule modulators of G-protein-coupled receptor 40 (GPR40/FFA1/FFAR1): an emerging target for type 2 diabetes.Low affinity GPCRs for metabolic intermediates: challenges for pharmacologists.Heterodimerisation of G protein-coupled receptors: implications for drug design and ligand screening.Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4.GPR40 agonists for the treatment of type 2 diabetes: life after 'TAKing' a hit.The Role and Future of FFA1 as a Therapeutic Target.Evaluation of the insulin-releasing and glucose-lowering effects of GPR120 activation in pancreatic β-cells.Free Fatty Acid Receptor 1 (FFAR1) as an Emerging Therapeutic Target for Type 2 Diabetes Mellitus: Recent Progress and Prevailing Challenges.Drug discovery opportunities and challenges at g protein coupled receptors for long chain free Fatty acids.Effects of a treatment with Se-rich rice flour high in resistant starch on enteric dysbiosis and chronic inflammation in diabetic ICR mice.Ligands at Free Fatty Acid Receptor 1 (GPR40).A synthetic free fatty acid-regulated transgene switch in mammalian cells and mice
P2860
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P2860
Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5'-O-(3-[35S]thio)triphosphate binding studies reflects binding of an endogenous agonist
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2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
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2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Uncovering the pharmacology of ...... nding of an endogenous agonist
@ast
Uncovering the pharmacology of ...... nding of an endogenous agonist
@en
Uncovering the pharmacology of ...... nding of an endogenous agonist
@nl
type
label
Uncovering the pharmacology of ...... nding of an endogenous agonist
@ast
Uncovering the pharmacology of ...... nding of an endogenous agonist
@en
Uncovering the pharmacology of ...... nding of an endogenous agonist
@nl
prefLabel
Uncovering the pharmacology of ...... nding of an endogenous agonist
@ast
Uncovering the pharmacology of ...... nding of an endogenous agonist
@en
Uncovering the pharmacology of ...... nding of an endogenous agonist
@nl
P356
P1476
Uncovering the pharmacology of ...... nding of an endogenous agonist
@en
P2093
Andrew J Brown
Leigh A Stoddart
P304
P356
10.1124/MOL.106.031534
P407
P577
2007-04-01T00:00:00Z