Thiazolidinediones induce osteocyte apoptosis by a G protein-coupled receptor 40-dependent mechanism.
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p38 MAPK Signaling in Osteoblast DifferentiationMinireview: Challenges and opportunities in development of PPAR agonistsDiabetes, bone and glucose-lowering agents: basic biology.Diet and gene interactions influence the skeletal response to polyunsaturated fatty acidsMinireview: nuclear receptor regulation of osteoclast and bone remodeling.Impact of oral antidiabetic agents on bone metabolism.G Protein-coupled Receptor 40 (GPR40) and Peroxisome Proliferator-activated Receptor γ (PPARγ): AN INTEGRATED TWO-RECEPTOR SIGNALING PATHWAY.GPR120: A bi-potential mediator to modulate the osteogenic and adipogenic differentiation of BMMSCsThe free fatty acid receptor G protein-coupled receptor 40 (GPR40) protects from bone loss through inhibition of osteoclast differentiation.Do thiazolidinediones still have a role in treatment of type 2 diabetes mellitus?The future of thiazolidinedione therapy in the management of type 2 diabetes mellitus.Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4.Adipose, bone and muscle tissues as new endocrine organs: role of reciprocal regulation for osteoporosis and obesity development.GPR40 agonists for the treatment of type 2 diabetes: life after 'TAKing' a hit.Oral anti-diabetic drugs and fracture risk, cut to the bone: safe or dangerous? A narrative review.Agonist-induced activation of human FFA1 receptor signals to extracellular signal-regulated kinase 1 and 2 through Gq- and Gi-coupled signaling cascades.The Role and Future of FFA1 as a Therapeutic Target.GPR40, a free fatty acid receptor, differentially impacts osteoblast behavior depending on differentiation stage and environment.PPARγ signaling and emerging opportunities for improved therapeutics.Rosiglitazone, a PPARγ agonist, ameliorates palmitate-induced insulin resistance and apoptosis in skeletal muscle cells.Diabetes Drug Effects on the Skeleton.Exendin-4 protects pancreatic beta cells from palmitate-induced apoptosis by interfering with GPR40 and the MKK4/7 stress kinase signalling pathway.
P2860
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P2860
Thiazolidinediones induce osteocyte apoptosis by a G protein-coupled receptor 40-dependent mechanism.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Thiazolidinediones induce oste ...... ceptor 40-dependent mechanism.
@ast
Thiazolidinediones induce oste ...... ceptor 40-dependent mechanism.
@en
type
label
Thiazolidinediones induce oste ...... ceptor 40-dependent mechanism.
@ast
Thiazolidinediones induce oste ...... ceptor 40-dependent mechanism.
@en
prefLabel
Thiazolidinediones induce oste ...... ceptor 40-dependent mechanism.
@ast
Thiazolidinediones induce oste ...... ceptor 40-dependent mechanism.
@en
P2093
P2860
P356
P1476
Thiazolidinediones induce oste ...... eceptor 40-dependent mechanism
@en
P2093
Aleksandra Mieczkowska
Daniel Chappard
Michel F Baslé
P2860
P304
23517-23526
P356
10.1074/JBC.M111.324814
P407
P577
2012-05-16T00:00:00Z