SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors - sprookjes - yvandenbroek - TriplyDB

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

http://www.wikidata.org/entity/Q28284908

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G6b, a novel immunoglobulin superfamily member encoded in the human major histocompatibility complex, interacts with SHP-1 and SHP-2 A THEMIS:SHP1 complex promotes T-cell survival Differential regulation of TCR-mediated gene transcription by Vav family members NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway Specific dephosphorylation of the Lck tyrosine protein kinase at Tyr-394 by the SHP-1 protein-tyrosine phosphatase SHP-1 regulation of p62(DOK) tyrosine phosphorylation in macrophages Association of 3BP2 with SHP-1 regulates SHP-1-mediated production of TNF-α in RBL-2H3 cells.SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels Insufficient phosphorylation prevents fc gamma RIIB from recruiting the SH2 domain-containing protein-tyrosine phosphatase SHP-1.Novel SHP-1 inhibitors tyrosine phosphatase inhibitor-1 and analogs with preclinical anti-tumor activities as tolerated oral agents.How to extinguish lymphocyte activation, immunotyrosine-based inhibition motif (ITIM)-bearing molecules a solution?Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2.SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells.Functional requirements for inhibitory signal transmission by the immunomodulatory receptor CD300a.Molecular underpinning of B-cell anergy.Natural killer cells and the syndrome of chronic natural killer cell lymphocytosis.SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells The conundrum of inhibitory signaling by ITAM-containing immunoreceptors: potential molecular mechanisms.The transmembrane adapter LAT plays a central role in immune receptor signalling.Intracellular signaling by the killer immunoglobulin-like receptors and Ly49.ITAMs versus ITIMs: striking a balance during cell regulation.NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells.Human natural killer cell receptors and signal transduction.Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells Natural killer cell activation in mice and men: different triggers for similar weapons?Vav1 dephosphorylation by the tyrosine phosphatase SHP-1 as a mechanism for inhibition of cellular cytotoxicity.Phosphatase inhibitor, sodium stibogluconate, in combination with interferon (IFN) alpha 2b: phase I trials to identify pharmacodynamic and clinical effects.A balance between positive and negative signals in cytotoxic lymphocytes regulates the polarization of lipid rafts during the development of cell-mediated killing Protein tyrosine phosphatase function: the substrate perspective.A new look at T cell receptor signaling to nuclear factor-κB Dynamin 2 regulates granule exocytosis during NK cell-mediated cytotoxicity SHP-2 expression negatively regulates NK cell function.Shp1 function in myeloid cells.Dephosphorylation of the adaptor LAT and phospholipase C-γ by SHP-1 inhibits natural killer cell cytotoxicity.PI3K links NKG2D signaling to a CrkL pathway involved in natural killer cell adhesion, polarity, and granule secretion.Reduction of hematopoietic cell-specific tyrosine phosphatase SHP-1 gene expression in natural killer cell lymphoma and various types of lymphomas/leukemias : combination analysis with cDNA expression array and tissue microarray.Requirement for CD28 co-stimulation is lower in SHP-1-deficient T cells.

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P2860

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

http://www.wikidata.org/entity/Q28284908

description

1998 nî lūn-bûn

@nan

1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

@ast

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

@en

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

@nl

type

label

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

@ast

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

@en

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

@nl

prefLabel

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

@ast

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

@en

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

@nl

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Journal of Biological Chemistry

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SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

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P2093

B L Williams

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D D Billadeau

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G A Koretzky

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N Fang

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P J Leibson

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R T Abraham

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T Yi

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P2860

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

Intramolecular regulation of protein tyrosine phosphatase SH-PTP1: a new function for Src homology 2 domains

Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells

Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk

Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor

Differential functions of the two Src homology 2 domains in protein tyrosine phosphatase SH-PTP1

A novel phosphotyrosine motif with a critical amino acid at position -2 for the SH2 domain-mediated activation of the tyrosine phosphatase SHP-1

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27518-27523

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scholarly article

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10.1074/JBC.273.42.27518

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42

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P478

273

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Bryce A. Binstadt

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1998-10-01T00:00:00Z

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P5875

13521362

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9765283

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