Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells - sprookjes - yvandenbroek - TriplyDB

Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells

Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells

http://www.wikidata.org/entity/Q34600774

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Cell biological steps and checkpoints in accessing NK cell cytotoxicity The role of natural cytotoxicity receptors in various pathologies: emphasis on type I diabetes Natural killer cell tolerance: control by self or self-control?Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells SHP-1 phosphatase is a critical regulator in preventing natural killer cell self-killing Diacylglycerol kinase α establishes T cell polarity by shaping diacylglycerol accumulation at the immunological synapse A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.A Generalizable Platform for the Photoactivation of Cell Surface Receptors.Balancing natural killer cell activation through paired receptors.A single amino acid change in inhibitory killer cell Ig-like receptor results in constitutive receptor self-association and phosphorylation.Retargeting T cells to GD2 pentasaccharide on human tumors using Bispecific humanized antibody.Imaging of Cell-Cell Communication in a Vertical Orientation Reveals High-Resolution Structure of Immunological Synapse and Novel PD-1 Dynamics.The adaptor protein Crk controls activation and inhibition of natural killer cells.The Size of Activating and Inhibitory Killer Ig-like Receptor Nanoclusters Is Controlled by the Transmembrane Sequence and Affects Signaling NK cell tolerance of self-specific activating receptor KIR2DS1 in individuals with cognate HLA-C2 ligand Successful engineering of a highly potent single-chain variable-fragment (scFv) bispecific antibody to target disialoganglioside (GD2) positive tumors Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse.Controlling natural killer cell responses: integration of signals for activation and inhibition.NK cell development, homeostasis and function: parallels with CD8⁺ T cells.Building tolerance by dismantling synapses: inhibitory receptor signaling in natural killer cells.New views of the human NK cell immunological synapse: recent advances enabled by super- and high-resolution imaging techniques.The central role of the cytoskeleton in mechanisms and functions of the NK cell immune synapse.Activation of Lymphocyte Cytolytic Machinery: Where are We?Redirected Primary Human Chimeric Antigen Receptor Natural Killer Cells As an "Off-the-Shelf Immunotherapy" for Improvement in Cancer Treatment.Suppressing the killer instinct.The ap-2 clathrin adaptor mediates endocytosis of an inhibitory killer cell Ig-like receptor in human NK cells.Visualization of the immunological synapse by dual color time-gated stimulated emission depletion (STED) nanoscopy.Cell-mediated autophagy promotes cancer cell survival.KIR3DL1 and HLA-B Density and Binding Calibrate NK Education and Response to HIV.The Planar Lipid Bilayer System Serves as a Reductionist Approach for Studying NK Cell Immunological Synapses and Their Functions.Inhibitory receptor signaling destabilizes immunological synapse formation in primary NK cells.Illuminating the dynamics of signal integration in Natural Killer cells.Superresolution microscopy reveals nanometer-scale reorganization of inhibitory natural killer cell receptors upon activation of NKG2D.Probing Synaptic Biomechanics Using Micropillar Arrays.Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells.Natural Killer Cell Education and the Response to Infection and Cancer Therapy: Stay Tuned.Actin retrograde flow controls natural killer cell response by regulating the conformation state of SHP-1.Natural killer cells commute death sentence.

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P2860

Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells

http://www.wikidata.org/entity/Q34600774

description

2011 nî lūn-bûn

@nan

2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

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2011年论文

@wuu

name

Inhibitory signaling blocks ac ...... action in natural killer cells

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Inhibitory signaling blocks ac ...... action in natural killer cells

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Inhibitory signaling blocks ac ...... action in natural killer cells

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type

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Inhibitory signaling blocks ac ...... action in natural killer cells

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Inhibitory signaling blocks ac ...... action in natural killer cells

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Inhibitory signaling blocks ac ...... action in natural killer cells

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Inhibitory signaling blocks ac ...... action in natural killer cells

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Inhibitory signaling blocks ac ...... action in natural killer cells

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Inhibitory signaling blocks ac ...... action in natural killer cells

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Inhibitory signaling blocks ac ...... action in natural killer cells

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Ernesto Merino

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Morgan Huse

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Thushara P Abeyweera

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P2860

Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases

Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor

Regulatory and signaling properties of the Vav family

The human natural killer cell immune synapse

Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling.

Natural killer cell signal integration balances synapse symmetry and migration

Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand

Engagement of the inhibitory receptor CD158a interrupts TCR signaling, preventing dynamic membrane reorganization in CTL/tumor cell interaction

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

Inhibitory receptor signaling via tyrosine phosphorylation of the adaptor Crk

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675-690

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scholarly article

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10.1083/JCB.201009135

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21339333

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