Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus - sprookjes - yvandenbroek - TriplyDB

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

http://www.wikidata.org/entity/Q28345088

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Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation PR72, a novel regulator of Wnt signaling required for Naked cuticle function Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex Nuclear export and centrosome targeting of the protein phosphatase 2A subunit B56alpha: role of B56alpha in nuclear export of the catalytic subunit Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex Wnt signaling: the good and the bad The links between axin and carcinogenesis Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex The broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance Regulation of the Wnt/β-Catenin Signaling Pathway by Human Papillomavirus E6 and E7 Oncoproteins Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin beta-catenin destruction complex: insights and questions from a structural perspective Molecular basis for PP2A regulatory subunit B56alpha targeting in cardiomyocytes Phosphoprotein phosphatase-2A docks to Dishevelled and counterregulates Wnt3a/beta-catenin signaling.Regulation of c-Myc Protein Abundance by a Protein Phosphatase 2A-Glycogen Synthase Kinase 3β-Negative Feedback Pathway.Identification of a novel conserved mixed-isoform B56 regulatory subunit and spatiotemporal regulation of protein phosphatase 2A during Xenopus laevis development.A novel functional screen in human cells identifies MOCA as a negative regulator of Wnt signaling.Selective inhibition of IFNG-induced autophagy by Mir155- and Mir31-responsive WNT5A and SHH signaling Quantification of beta-catenin signaling components in colon cancer cell lines, tissue sections, and microdissected tumor cells using reaction monitoring mass spectrometry.CIP2A mediates fibronectin-induced bladder cancer cell proliferation by stabilizing β-catenin.Patterning and gastrulation defects caused by the tw18 lethal are due to loss of Ppp2r1a.PP2A inhibitors suppress migration and growth of PANC-1 pancreatic cancer cells through inhibition on the Wnt/β-catenin pathway by phosphorylation and degradation of β-catenin.Two conserved domains in regulatory B subunits mediate binding to the A subunit of protein phosphatase 2A.Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer.A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins.Genetic and epigenetic changes of components affecting the WNT pathway in colorectal carcinomas stratified by microsatellite instability Casein kinase I in the mammalian circadian clock pp32 reduction induces differentiation of TSU-Pr1 cells.Parameter-free methods distinguish Wnt pathway models and guide design of experiments.Regulation of nuclear-cytoplasmic shuttling and function of Family with sequence similarity 13, member A (Fam13a), by B56-containing PP2As and Akt.Phosphatases: the new brakes for cancer development?Evolutionary Analysis of the B56 Gene Family of PP2A Regulatory Subunits.A Nonsynonymous/Synonymous Substitution Analysis of the B56 Gene Family Aids in Understanding B56 Isoform Diversity.Functional genomics analyses of differential macaque peripheral blood mononuclear cell infections by human immunodeficiency virus-1 and simian immunodeficiency virus ReSETting PP2A tumour suppressor activity in blast crisis and imatinib-resistant chronic myelogenous leukaemia.Cardiomyocyte specific deletion of PP2A causes cardiac hypertrophy.

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P2860

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

http://www.wikidata.org/entity/Q28345088

description

2001 nî lūn-bûn

@nan

2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2001年の論文

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2001年論文

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2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

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2001年論文

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2001年论文

@wuu

name

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

@ast

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

@en

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

@nl

type

label

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

@ast

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

@en

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

@nl

prefLabel

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

@ast

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

@en

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

@nl

P1433

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The EMBO Journal

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Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

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P2093

D M Virshup

http://www.w3.org/2001/XMLSchema#string

H J Yost

http://www.w3.org/2001/XMLSchema#string

J M Seeling

http://www.w3.org/2001/XMLSchema#string

X Li

http://www.w3.org/2001/XMLSchema#string

P2860

DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin

The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin.

A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

PPX, a novel protein serine/threonine phosphatase localized to centrosomes.

Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers

Lessons from hereditary colorectal cancer

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4122-31

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450002

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10.1093/EMBOJ/20.15.4122

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15

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11858660

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11483515

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149155

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