Notch signalling synchronizes the zebrafish segmentation clock but is not needed to create somite boundaries
about
What can vertebrates tell us about segmentation?Faster embryonic segmentation through elevated Delta-Notch signalling.Stochastic Regulation of her1/7 Gene Expression Is the Source of Noise in the Zebrafish Somite Clock Counteracted by Notch Signallingα5β1 integrin-mediated adhesion to fibronectin is required for axis elongation and somitogenesis in miceA multi-cell, multi-scale model of vertebrate segmentation and somite formationSomitogenesis clock-wave initiation requires differential decay and multiple binding sites for clock proteinA spatio-temporal model of Notch signalling in the zebrafish segmentation clock: conditions for synchronised oscillatory dynamicsDelta-Notch signalling in segmentationQuantitative and logic modelling of molecular and gene networksSomitogenesisTbx protein level critical for clock-mediated somite positioning is regulated through interaction between Tbx and RipplyNotch is a critical component of the mouse somitogenesis oscillator and is essential for the formation of the somitesDelayed coupling theory of vertebrate segmentation.Random cell movement promotes synchronization of the segmentation clockSingle-cell-resolution imaging of the impact of Notch signaling and mitosis on segmentation clock dynamicsSpatial gradients of protein-level time delays set the pace of the traveling segmentation clock waves.From signals to patterns: space, time, and mathematics in developmental biology.Turn It Down a NotchDickkopf1--a new player in modelling the Wnt pathway.Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.Genetic oscillations. A Doppler effect in embryonic pattern formation.Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation.Zebrafish foxc1a plays a crucial role in early somitogenesis by restricting the expression of aldh1a2 directly.Dynamics of the slowing segmentation clock reveal alternating two-segment periodicity.Generation of dispersed presomitic mesoderm cell cultures for imaging of the zebrafish segmentation clock in single cellsA balance of positive and negative regulators determines the pace of the segmentation clockInterfering with Wnt signalling alters the periodicity of the segmentation clock.Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis.Role of unusual O-glycans in intercellular signalingNotch signaling, the segmentation clock, and the patterning of vertebrate somites.Cyclic Nrarp mRNA expression is regulated by the somitic oscillator but Nrarp protein levels do not oscillate.The segmentation clock mechanism moves up a notch.Live cell imaging and systems biology.Vertebrate segmentation: from cyclic gene networks to scoliosis.Experiments, measurements, and mathematical modeling to decipher time signals in development.Oscillatory gene expression and somitogenesis.Signalling dynamics in vertebrate segmentation.Molecular mechanism for cyclic generation of somites: Lessons from mice and zebrafish.A framework for quantification and physical modeling of cell mixing applied to oscillator synchronization in vertebrate somitogenesis.Zebrafish phenotypic screen identifies novel Notch antagonists.
P2860
Q27027888-1A8A8AA7-A43A-4AD0-B807-A84174B1C144Q27313481-50C78211-314E-4A9A-A1D0-91547629BA4CQ27318039-64380D65-32E1-4A3F-A0D7-0A3BF589D483Q27332406-8639C935-B8FF-4472-A96D-4FEA031DC9A2Q27332728-05C96D03-A7A5-454B-88BC-638798172288Q27335009-B58788B6-735F-4797-8420-94C75B7CE52FQ27355549-D737463E-6B72-4ACF-872F-EBEFD2725E17Q28069407-1CB8BBA0-0EB8-4815-9A7A-A1C4F2E12D32Q28083248-BAFEFD23-38B0-4223-8AB5-F1280654D241Q28269656-23FC86AA-F6FD-4E20-B256-87C957A9A1B3Q28543283-E90C34E7-1337-4496-8190-40ACA232C3DBQ28590793-EF448B3E-B690-4DCD-B2C8-190A9621001EQ30487939-E272E6E9-05E8-4E02-A1EC-7C039A9657FAQ30493790-CD2AF408-2A67-4BA6-86C7-D39ADC6C6B7AQ30528453-97D023DB-C9F4-4B47-89C9-C90BE737B2D5Q30617464-8E48839D-C76E-4BDC-BE8A-6DBAF2CBC086Q33346156-0A4FC3D7-BC42-45F3-8084-0B6E4E13606FQ33364683-2B0C5969-E0F0-4C42-8E31-990A3482FC21Q34055635-F100F9FA-5087-4449-98B9-36C7F28B3213Q34154195-FA8264A8-45C9-46EE-8D93-0CD0A7797935Q34428712-E77AAB71-0AC0-426E-A26C-8B32E932D1A8Q34809773-DD246EE9-E8AD-4509-ACD3-3EE601522707Q35451072-FD510DC8-B1D0-40A7-8D93-F1C46756D8A6Q35635073-7E25D903-A8EE-4160-BB01-964E3578D1A8Q35879220-65DB07B2-520B-4419-A1EF-766BDFD12331Q36146536-9590740F-D855-4289-9FA5-A6CB4E7B08E9Q37201732-ACE08DF4-C6C3-48A3-920A-BA0D854C6C70Q37229838-3FF448C0-2DC4-4817-AC38-D1D783D3AAFBQ37308624-9F6E6C90-4C83-4529-AB67-FF4E3806EA76Q37503775-85541CA2-34A2-45F0-B132-96A094E4359BQ37592411-7A4E3F01-7B5D-4BF2-8B4C-9B1D56EC52B8Q37781196-0AC9D577-8D08-4E25-92DF-EEF1783E851FQ37781761-0728415A-C7F3-4A29-9EB6-04ECCA1B2170Q37881028-304BB546-817F-486B-924F-E5729C8B5A29Q38018288-8F6147B2-DC4B-41FA-A871-61F5420AB1A2Q38116917-6A753EF0-7330-4684-88E1-B7AF6C7865A6Q38261780-623F5E20-6337-458B-9737-DEF9EBE254EEQ38671655-FB470905-686E-4AD4-8E0D-2A9F0DB22B85Q38708057-9BDC48ED-2EFF-4A42-BC6A-7B70DCE9EBE6Q39036896-69E61619-CD54-4A6F-AA28-8CB8BED44B2D
P2860
Notch signalling synchronizes the zebrafish segmentation clock but is not needed to create somite boundaries
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Notch signalling synchronizes ...... ed to create somite boundaries
@ast
Notch signalling synchronizes ...... ed to create somite boundaries
@en
Notch signalling synchronizes ...... ed to create somite boundaries
@nl
type
label
Notch signalling synchronizes ...... ed to create somite boundaries
@ast
Notch signalling synchronizes ...... ed to create somite boundaries
@en
Notch signalling synchronizes ...... ed to create somite boundaries
@nl
prefLabel
Notch signalling synchronizes ...... ed to create somite boundaries
@ast
Notch signalling synchronizes ...... ed to create somite boundaries
@en
Notch signalling synchronizes ...... ed to create somite boundaries
@nl
P2860
P3181
P1433
P1476
Notch signalling synchronizes ...... ed to create somite boundaries
@en
P2093
Ertuğrul M Ozbudak
Julian Lewis
P2860
P3181
P356
10.1371/JOURNAL.PGEN.0040015
P407
P577
2008-02-01T00:00:00Z