Setting the tempo in development: an investigation of the zebrafish somite clock mechanism
about
Pulsed feedback defers cellular differentiationStochastic Regulation of her1/7 Gene Expression Is the Source of Noise in the Zebrafish Somite Clock Counteracted by Notch SignallingA multi-cell, multi-scale model of vertebrate segmentation and somite formationSomitogenesis clock-wave initiation requires differential decay and multiple binding sites for clock proteinA spatio-temporal model of Notch signalling in the zebrafish segmentation clock: conditions for synchronised oscillatory dynamicsDelta-Notch signalling in segmentationNotch signalling synchronizes the zebrafish segmentation clock but is not needed to create somite boundariesTopology and dynamics of the zebrafish segmentation clock core circuitDelta1 expression, cell cycle exit, and commitment to a specific secretory fate coincide within a few hours in the mouse intestinal stem cell systemAn analysis of segmentation dynamics throughout embryogenesis in the centipede Strigamia maritimaDelayed coupling theory of vertebrate segmentation.Random cell movement promotes synchronization of the segmentation clockSingle-cell-resolution imaging of the impact of Notch signaling and mitosis on segmentation clock dynamicsA segmentation clock operating in blastoderm and germband stages of Tribolium development.Spatial gradients of protein-level time delays set the pace of the traveling segmentation clock waves.From signals to patterns: space, time, and mathematics in developmental biology.Intron delays and transcriptional timing during development.Modeling the zebrafish segmentation clock's gene regulatory network constrained by expression data suggests evolutionary transitions between oscillating and nonoscillating transcriptionAn iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development.Dickkopf1--a new player in modelling the Wnt pathway.Rbm24a and Rbm24b are required for normal somitogenesis.Expression of the oscillating gene her1 is directly regulated by Hairy/Enhancer of Split, T-box, and Suppressor of Hairless proteins in the zebrafish segmentation clock.Genetic oscillations. A Doppler effect in embryonic pattern formation.ACME: automated cell morphology extractor for comprehensive reconstruction of cell membranes.Intronic delay is essential for oscillatory expression in the segmentation clockModels in biology: 'accurate descriptions of our pathetic thinking'.Making sense in biology: an appreciation of Julian Lewis.Dynamics of the slowing segmentation clock reveal alternating two-segment periodicity.Generation of dispersed presomitic mesoderm cell cultures for imaging of the zebrafish segmentation clock in single cellsAncient role of ten-m/odz in segmentation and the transition from sequential to syncytial segmentation.Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock.Silver nanoparticles incite size- and dose-dependent developmental phenotypes and nanotoxicity in zebrafish embryos.Neocortical neurogenesis: morphogenetic gradients and beyond.Transcript processing and export kinetics are rate-limiting steps in expressing vertebrate segmentation clock genes.Notch signaling, the segmentation clock, and the patterning of vertebrate somites.Progress and perspective of TBX6 gene in congenital vertebral malformations.The segmentation clock mechanism moves up a notch.Vertebrate segmentation: from cyclic gene networks to scoliosis.Computational approaches to developmental patterning.Experiments, measurements, and mathematical modeling to decipher time signals in development.
P2860
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P2860
Setting the tempo in development: an investigation of the zebrafish somite clock mechanism
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Setting the tempo in developme ...... brafish somite clock mechanism
@ast
Setting the tempo in developme ...... brafish somite clock mechanism
@en
type
label
Setting the tempo in developme ...... brafish somite clock mechanism
@ast
Setting the tempo in developme ...... brafish somite clock mechanism
@en
prefLabel
Setting the tempo in developme ...... brafish somite clock mechanism
@ast
Setting the tempo in developme ...... brafish somite clock mechanism
@en
P2093
P2860
P1433
P1476
Setting the tempo in developme ...... brafish somite clock mechanism
@en
P2093
Ertuğrul M Ozbudak
François Giudicelli
Julian Lewis
P2860
P356
10.1371/JOURNAL.PBIO.0050150
P407
P577
2007-06-01T00:00:00Z