Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading - sprookjes - yvandenbroek - TriplyDB

Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading

Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading

http://www.wikidata.org/entity/Q28481462

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Recent progress in osteocyte research Physiological mechanisms and therapeutic potential of bone mechanosensing.Primary cilia-mediated mechanotransduction in human mesenchymal stem cells.The primary cilium functions as a mechanical and calcium signaling nexus Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts.Function and regulation of primary cilia and intraflagellar transport proteins in the skeleton Biological and Chemical Removal of Primary Cilia Affects Mechanical Activation of Chondrogenesis Markers in Chondroprogenitors and Hypertrophic Chondrocytes Mechanical signals promote osteogenic fate through a primary cilia-mediated mechanism Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation A pre-clinical murine model of oral implant osseointegration.Disruption of kif3a results in defective osteoblastic differentiation in dental mesenchymal stem/precursor cells via the Wnt signaling pathway.KIF3A binds to β-arrestin for suppressing Wnt/β-catenin signalling independently of primary cilia in lung cancer.Adenylyl cyclase 6 mediates loading-induced bone adaptation in vivo.Role of Osteocyte-derived Insulin-Like Growth Factor I in Developmental Growth, Modeling, Remodeling, and Regeneration of the Bone.The primary cilium as a novel extracellular sensor in bone Emerging role of primary cilia as mechanosensors in osteocytes Osteocyte Mechanobiology.Primary Cilia and Intraflagellar Transport Proteins in Bone and Cartilage.Bone cell mechanosensation of fluid flow stimulation: a fluid-structure interaction model characterising the role integrin attachments and primary cilia.The growth plate's response to load is partially mediated by mechano-sensing via the chondrocytic primary cilium.Functional Diversity of Ciliary Proteins in Bone Development and Disease.TGFβ1 - induced recruitment of human bone mesenchymal stem cells is mediated by the primary cilium in a SMAD3-dependent manner.Primary cilia act as mechanosensors during bone healing around an implant The multi-faceted role of the actin cap in cellular mechanosensation and mechanotransduction.KIF3A and IL-4 are disease-specific biomarkers for psoriatic arthritis susceptibility.Primary cilia: Cell and molecular mechanosensors directing whole tissue function.TGF-β1 impairs mechanosensation of human osteoblasts via HDAC6-mediated shortening and distortion of primary cilia.Primary cilia exist in a small fraction of cells in trabecular bone and marrow.Lengthening primary cilia enhances cellular mechanosensitivity.Baby fish working out: an epigenetic source of adaptive variation in the cichlid jaw.Sending mixed signals: Cilia-dependent signaling during development and disease.

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Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading

http://www.wikidata.org/entity/Q28481462

description

2012 nî lūn-bûn

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2012 թուականին հրատարակուած գիտական յօդուած

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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Mechanosensing by the primary ...... bone formation due to loading

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Mechanosensing by the primary ...... bone formation due to loading

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Mechanosensing by the primary ...... bone formation due to loading

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Mechanosensing by the primary ...... bone formation due to loading

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Alesha B Castillo

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Christopher R Jacobs

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Jill A Helms

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Sara Temiyasathit

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Stefanie D Monica

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W Joyce Tang

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P2860

Generalized lacZ expression with the ROSA26 Cre reporter strain

Vertebrate Smoothened functions at the primary cilium.

Intraflagellar transport

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling

Cilia and Hedgehog responsiveness in the mouse

Association of the testis-specific TRIM/RBCC protein RNF33/TRIM60 with the cytoplasmic motor proteins KIF3A and KIF3B

Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II

Hedgehog signalling in the mouse requires intraflagellar transport proteins

Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli

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Charles T Anderson

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