Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation
about
Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1A novel role of Sprouty 2 in regulating cellular apoptosisDistinct requirements for the Sprouty domain for functional activity of Spred proteinsFunctional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancersExpression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational controlA functional interaction between sprouty proteins and caveolin-1FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasisIdentification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathwaysCoordinating ERK/MAPK signalling through scaffolds and inhibitorsSystematic analysis of copy number variants of a large cohort of orofacial cleft patients identifies candidate genes for orofacial clefts.Regulation of sprouty stability by Mnk1-dependent phosphorylation.Modeling cancer progression via pathway dependenciesDecreased expression of Sprouty2 in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder: a correlation with BDNF expression.How Genetics Has Helped Piece Together the MAPK Signaling Pathway.A quantitative image cytometry technique for time series or population analyses of signaling networks.HECT domain-containing E3 ubiquitin ligase Nedd4 interacts with and ubiquitinates Sprouty2.Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loopThe expression of the Sprouty 1 protein inversely correlates with growth, proliferation, migration and invasion of ovarian cancer cellsSprouty2 and Spred1-2 proteins inhibit the activation of the ERK pathway elicited by cyclopentenone prostanoidsThe developing story of Sprouty and cancer.Axotomy-induced miR-21 promotes axon growth in adult dorsal root ganglion neurons.Sprouty1, a new target of the angiostatic agent 16K prolactin, negatively regulates angiogenesis.Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway.Sprouty proteins inhibit receptor-mediated activation of phosphatidylinositol-specific phospholipase C.Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation.G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation.Sprouty4 is an endogenous negative modulator of TrkA signaling and neuronal differentiation induced by NGFChange or die: targeting adaptive signaling to kinase inhibition in cancer cells.The aged niche disrupts muscle stem cell quiescence.Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis.The Sprouty-related protein, Spred-1, localizes in a lipid raft/caveola and inhibits ERK activation in collaboration with caveolin-1.Conditional ablation of Pten in osteoprogenitors stimulates FGF signalingBCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcomaSpry1 and Spry4 differentially regulate human aortic smooth muscle cell phenotype via Akt/FoxO/myocardin signalingExpression and functional role of sprouty-2 in breast morphogenesis.Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.Shoc2/Sur8 protein regulates neurite outgrowthMicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy.Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrainNegative Regulation of Receptor Tyrosine Kinase (RTK) Signaling: A Developing Field
P2860
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P2860
Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation
description
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im Dezember 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/12/07)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/12/07)
@nl
наукова стаття, опублікована в грудні 2001
@uk
name
Mammalian sprouty proteins inh ...... n by preventing ras activation
@ast
Mammalian sprouty proteins inh ...... n by preventing ras activation
@en
Mammalian sprouty proteins inh ...... n by preventing ras activation
@nl
type
label
Mammalian sprouty proteins inh ...... n by preventing ras activation
@ast
Mammalian sprouty proteins inh ...... n by preventing ras activation
@en
Mammalian sprouty proteins inh ...... n by preventing ras activation
@nl
prefLabel
Mammalian sprouty proteins inh ...... n by preventing ras activation
@ast
Mammalian sprouty proteins inh ...... n by preventing ras activation
@en
Mammalian sprouty proteins inh ...... n by preventing ras activation
@nl
P2093
P2860
P921
P3181
P356
P1476
Mammalian sprouty proteins inh ...... n by preventing ras activation
@en
P2093
P2860
P304
46460–46468
P3181
P356
10.1074/JBC.M108234200
P407
P577
2001-12-07T00:00:00Z