The transcription factor NF-ATc is essential for cardiac valve formation
about
NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and JunChondromodulin-I maintains cardiac valvular function by preventing angiogenesisCalreticulin signals upstream of calcineurin and MEF2C in a critical Ca(2+)-dependent signaling cascadeTargeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growthModulation of T cell cytokine production by interferon regulatory factor-4The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel diseaseThe DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitmentIntegration of calcium and cyclic AMP signaling pathways by 14-3-3An ORFeome-based analysis of human transcription factor genes and the construction of a microarray to interrogate their expressionImmunological function in mice lacking the Rac-related GTPase RhoGFOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1NFAT: ubiquitous regulator of cell differentiation and adaptationCharacterization of DNA binding, transcriptional activation, and regulated nuclear association of recombinant human NFATpCell cycle and apoptosis regulation by NFAT transcription factors: new roles for an old playerDevelopment of the mammalian lymphatic vasculatureArchitecture and expression of the nfatc1 gene in lymphocytesUnderstanding the pathogenesis of Kawasaki disease by network and pathway analysisConserved transcriptional regulatory mechanisms in aortic valve development and diseaseGene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesisInhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes.Development of the endocardium.Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae.Yeast calcineurin regulates nuclear localization of the Crz1p transcription factor through dephosphorylationTargeted deletion of Hand2 in cardiac neural crest-derived cells influences cardiac gene expression and outflow tract developmentAtrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart.Nf1 has an essential role in endothelial cellsEssential role of Sox9 in the pathway that controls formation of cardiac valves and septaCardiac defects and renal failure in mice with targeted mutations in Pkd2NFATc1 balances quiescence and proliferation of skin stem cellsEndocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesisNovel interactions between NFATc1 (Nuclear Factor of Activated T cells c1) and STAT-3 (Signal Transducer and Activator of Transcription-3) mediate G protein-coupled receptor agonist, thrombin-induced biphasic expression of cyclin D1, with first phasNFATc1 targets cyclin A in the regulation of vascular smooth muscle cell multiplication during restenosisOpposing roles of FoxP1 and Nfat3 in transcriptional control of cardiomyocyte hypertrophyRequirement of transcription factor NFAT in developing atrial myocardiumActivity-dependent repression of muscle genes by NFATLack of periostin leads to suppression of Notch1 signaling and calcific aortic valve diseaseAblation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal developmentImpairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryosMsx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardiumNFATc1 regulates lymphatic endothelial development
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P2860
The transcription factor NF-ATc is essential for cardiac valve formation
description
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 1998
@ast
scientific journal article
@en
vedecký článok (publikovaný 1998/03/12)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/03/12)
@nl
наукова стаття, опублікована в березні 1998
@uk
مقالة علمية (نشرت في 12-3-1998)
@ar
name
The transcription factor NF-ATc is essential for cardiac valve formation
@ast
The transcription factor NF-ATc is essential for cardiac valve formation
@en
The transcription factor NF-ATc is essential for cardiac valve formation
@nl
type
label
The transcription factor NF-ATc is essential for cardiac valve formation
@ast
The transcription factor NF-ATc is essential for cardiac valve formation
@en
The transcription factor NF-ATc is essential for cardiac valve formation
@nl
prefLabel
The transcription factor NF-ATc is essential for cardiac valve formation
@ast
The transcription factor NF-ATc is essential for cardiac valve formation
@en
The transcription factor NF-ATc is essential for cardiac valve formation
@nl
P2093
P2860
P3181
P356
P1433
P1476
The transcription factor NF-ATc is essential for cardiac valve formation
@en
P2093
A. M. Ranger
C. Mickanin
E. M. Gravallese
F. C. de la Brousse
H. S. Baldwin
L. H. Glimcher
M. J. Grusby
M. R. Hodge
P2860
P2888
P304
P3181
P356
10.1038/32426
P407
P577
1998-03-12T00:00:00Z
P6179
1049183837