Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity
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Electrical activity as a developmental regulator in the formation of spinal cord circuitsFunctional Diversification of Motor Neuron-specific Isl1 Enhancers during EvolutionCharacterization of the Gbx1-/- mouse mutant: a requirement for Gbx1 in normal locomotion and sensorimotor circuit developmentStructural Basis for Partial Redundancy in a Class of Transcription Factors, the LIM Homeodomain Proteins, in Neural Cell Type SpecificationHair cell overexpression of Islet1 reduces age-related and noise-induced hearing loss.The Isl1-Lhx3 Complex Promotes Motor Neuron Specification by Activating Transcriptional Pathways that Enhance Its Own Expression and FormationLoss of LMO4 in the retina leads to reduction of GABAergic amacrine cells and functional deficits.Interactions between LHX3- and ISL1-family LIM-homeodomain transcription factors are conserved in Caenorhabditis elegansExpression of Isl1 during mouse developmentSpinal neurons require Islet1 for subtype-specific differentiation of electrical excitability.Islet-1 Is essential for pancreatic β-cell function.SSDP cofactors regulate neural patterning and differentiation of specific axonal projectionsDistinct cis regulatory elements govern the expression of TAG1 in embryonic sensory ganglia and spinal cordCholestenoic acids regulate motor neuron survival via liver X receptors.Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice.The structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4.Isl1 is required for multiple aspects of motor neuron development.Slit and Semaphorin signaling governed by Islet transcription factors positions motor neuron somata within the neural tubeFusion protein Isl1-Lhx3 specifies motor neuron fate by inducing motor neuron genes and concomitantly suppressing the interneuron programs.Transcription factor ISL1 is essential for pacemaker development and function.Lmo4 establishes rostral motor cortex projection neuron subtype diversity.Conditionally immortalized stem cell lines from human spinal cord retain regional identity and generate functional V2a interneurons and motorneurons.Islet1 deletion causes kidney agenesis and hydroureter resembling CAKUT.ISL1-based LIM complexes control Slit2 transcription in developing cranial motor neurons.LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.Generating spinal motor neuron diversity: a long quest for neuronal identity.Motor neurons and the generation of spinal motor neuron diversityThe LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells.Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification.Chip/Ldb1 interacts with Tailup/islet1 to regulate cardiac gene expression in Drosophila.High-efficiency motor neuron differentiation from human pluripotent stem cells and the function of Islet-1.A Quantitative Fluorescence-Based Assay for Assessing LIM Domain-Peptide Interactions.LMO4 functions as a co-activator of neurogenin 2 in the developing cortex.LIM domain only 4 protein promotes granulocyte colony-stimulating factor-induced signaling in neurons.The LIM-homeodomain protein islet dictates motor neuron electrical properties by regulating K(+) channel expression.Lmo4 and Other LIM domain only factors are necessary and sufficient for multiple retinal cell type development.The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis.Gata6 restricts Isl1 to the posterior of nascent hindlimb buds through Isl1 cis-regulatory modules.Disparate binding kinetics by an intrinsically disordered domain enables temporal regulation of transcriptional complex formation.Reciprocal Negative Regulation Between Lmx1a and Lmo4 Is Required for Inner Ear Formation.
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P2860
Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity
description
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im September 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/09/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/09/01)
@nl
наукова стаття, опублікована у вересні 2009
@uk
مقالة علمية (نشرت في سبتمبر 2009)
@ar
name
Islet-to-LMO stoichiometries c ...... n and V2a interneuron identity
@ast
Islet-to-LMO stoichiometries c ...... n and V2a interneuron identity
@en
Islet-to-LMO stoichiometries c ...... n and V2a interneuron identity
@nl
type
label
Islet-to-LMO stoichiometries c ...... n and V2a interneuron identity
@ast
Islet-to-LMO stoichiometries c ...... n and V2a interneuron identity
@en
Islet-to-LMO stoichiometries c ...... n and V2a interneuron identity
@nl
prefLabel
Islet-to-LMO stoichiometries c ...... n and V2a interneuron identity
@ast
Islet-to-LMO stoichiometries c ...... n and V2a interneuron identity
@en
Islet-to-LMO stoichiometries c ...... n and V2a interneuron identity
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Islet-to-LMO stoichiometries c ...... n and V2a interneuron identity
@en
P2093
Ami Bryson
Gordon N. Gill
Mi-Ryoung Song
Samuel L. Pfaff
Sylvia M. Evans
P2860
P304
P3181
P356
10.1242/DEV.037986
P407
P577
2009-09-01T00:00:00Z