Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice. - sprookjes - yvandenbroek - TriplyDB

Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice.

Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice.

http://www.wikidata.org/entity/Q35224570

about

Mechanisms of retinoic acid signalling and its roles in organ and limb development Reduced BMP signaling results in hindlimb fusion with lethal pelvic/urogenital organ aplasia: a new mouse model of sirenomelia Sirenomelia phenotype in bmp7;shh compound mutants: a novel experimental model for studies of caudal body malformations Shared Enhancer Activity in the Limbs and Phallus and Functional Divergence of a Limb-Genital cis-Regulatory Element in Snakes Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathway ISL1 directly regulates FGF10 transcription during human cardiac outflow formation.Genome-wide Twist1 occupancy in endocardial cushion cells, embryonic limb buds, and peripheral nerve sheath tumor cells.RA Acts in a Coherent Feed-Forward Mechanism with Tbx5 to Control Limb Bud Induction and Initiation.Impaired enteroendocrine development in intestinal-specific Islet1 mouse mutants causes impaired glucose homeostasis.β-catenin is required in the neural crest and mesencephalon for pituitary gland organogenesis.Isl1 and Ldb co-regulators of transcription are essential early determinants of mouse limb development Pitx1 broadly associates with limb enhancers and is enriched on hindlimb cis-regulatory elements Molecular and evolutionary basis of limb field specification and limb initiation.How the embryo makes a limb: determination, polarity and identity.ISLET1-Dependent β-Catenin/Hedgehog Signaling Is Required for Outgrowth of the Lower Jaw.Life-long preservation of the regenerative capacity in the fin and heart in zebrafish Isl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor.Isl1 mediates mesenchymal expansion in the developing external genitalia via regulation of Bmp4, Fgf10, and Wnt5a.PITX1 promotes chondrogenesis and myogenesis in mouse hindlimbs through conserved regulatory targets.Pitx1 directly modulates the core limb development program to implement hindlimb identity.Gata6 restricts Isl1 to the posterior of nascent hindlimb buds through Isl1 cis-regulatory modules.A novel genetic variant in the transcription factor Islet-1 exerts gain of function on myocyte enhancer factor 2C promoter activity.Developmental Mechanism of Limb Field Specification along the Anterior-Posterior Axis during Vertebrate Evolution.

P2860

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P2860

Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice.

http://www.wikidata.org/entity/Q35224570

description

2011 nî lūn-bûn

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2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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Islet1-mediated activation of ...... r hindlimb initiation in mice.

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Islet1-mediated activation of ...... r hindlimb initiation in mice.

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Austin Johnson

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Dennis D M O'Leary

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Hiroko Kawakami

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Junji Itou

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Mark Lewandoski

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Merce Marti

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Samuel Pfaff

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Setsuko Sahara

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Sylvia M Evans

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Yasuhiko Kawakami

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P2860

A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs

Functions of FGF signalling from the apical ectodermal ridge in limb development

The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor

Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation

Lack of beta-catenin affects mouse development at gastrulation

Fgf10 is essential for limb and lung formation

Isl1Cre reveals a common Bmp pathway in heart and limb development

Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos

Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity

Tbx5 and Tbx4 are not sufficient to determine limb-specific morphologies but have common roles in initiating limb outgrowth

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4465-4473

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10.1242/DEV.065359

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20

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138

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Juan Carlos Izpisúa Belmonte

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2011-10-01T00:00:00Z

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51661341

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21937598

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