STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells
about
Long Intergenic Non-Coding RNAs: Novel Drivers of Human Lymphocyte DifferentiationMechanisms underlying helper T-cell plasticity: implications for immune-mediated disease.Histone Posttranslational Modifications of CD4⁺ T Cell in Autoimmune DiseasesTrithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity.GRHL3/GET1 and trithorax group members collaborate to activate the epidermal progenitor differentiation program.Transcriptional and epigenetic regulation of T-helper lineage specification.Genome-Wide Gene Expression Profiling Revealed a Critical Role for GATA3 in the Maintenance of the Th2 Cell Identity.Hoxb4 overexpression in CD4 memory phenotype T cells increases the central memory population upon homeostatic proliferationChallenges and opportunities in targeting the menin-MLL interaction.T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production.Transcriptional regulatory networks for CD4 T cell differentiation.Hierarchical IL-5 expression defines a subpopulation of highly differentiated human Th2 cells.Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner.Poly (ADP-ribose) polymerase 14 and its enzyme activity regulates T(H)2 differentiation and allergic airway disease.Epigenetic regulation of IL-12-dependent T cell proliferation.Helper T-cell identity and evolution of differential transcriptomes and epigenomes.Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identityAkt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cellsT cell immunity as a tool for studying epigenetic regulation of cellular differentiationGata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression.Interleukin-4-mediated 15-lipoxygenase-1 trans-activation requires UTX recruitment and H3K27me3 demethylation at the promoter in A549 cells.E3 ubiquitin ligase Cbl-b suppresses proallergic T cell development and allergic airway inflammationEpigenetic plasticity of Cd8a locus during CD8(+) T-cell development and effector differentiation and reprogramming.The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis.Transcriptional regulation by STAT6.T-cell identity and epigenetic memory.Roles of repressive epigenetic machinery in lineage decision of T cells.Histone methyltransferase and histone methylation in inflammatory T-cell responses.Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis.Transcriptional regulation of T helper type 2 differentiation.Deciphering the epigenetic code of T lymphocytes.IFNγ Influences Epithelial Anti-viral Responses via Histone Methylation of the Rig-I Promoter.Spatial Interplay between Polycomb and Trithorax Complexes Controls Transcriptional Activity in T LymphocytesEpigenetic Alterations in Cellular Immunity: New Insights into Autoimmune Diseases.T Cell Receptor and Cytokine Signaling Can Function at Different Stages to Establish and Maintain Transcriptional Memory and Enable T Helper Cell Differentiation.Modeling TH 2 responses and airway inflammation to understand fundamental mechanisms regulating the pathogenesis of asthma.Epigenetic regulation of T-helper cell differentiation, memory, and plasticity in allergic asthma.Interleukin-25 initiates Th2 differentiation of human CD4(+) T cells and influences expression of its own receptor.Methylation of Gata3 protein at Arg-261 regulates transactivation of the Il5 gene in T helper 2 cells.
P2860
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P248
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P2860
STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells
description
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im Oktober 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/10/25)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/10/25)
@nl
наукова стаття, опублікована в жовтні 2010
@uk
مقالة علمية (نشرت في 25-10-2010)
@ar
name
STAT6-mediated displacement of ...... ssion in T helper type 2 cells
@ast
STAT6-mediated displacement of ...... ssion in T helper type 2 cells
@en
STAT6-mediated displacement of ...... ssion in T helper type 2 cells
@nl
type
label
STAT6-mediated displacement of ...... ssion in T helper type 2 cells
@ast
STAT6-mediated displacement of ...... ssion in T helper type 2 cells
@en
STAT6-mediated displacement of ...... ssion in T helper type 2 cells
@nl
prefLabel
STAT6-mediated displacement of ...... ssion in T helper type 2 cells
@ast
STAT6-mediated displacement of ...... ssion in T helper type 2 cells
@en
STAT6-mediated displacement of ...... ssion in T helper type 2 cells
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
STAT6-mediated displacement of ...... ssion in T helper type 2 cells
@en
P2093
Akinori Kanai
Atsushi Onodera
Makoto Kuwahara
Masakatsu Yamashita
Yusuke Endo
Yutaka Suzuki
P2860
P304
P3181
P356
10.1084/JEM.20100760
P407
P577
2010-10-25T00:00:00Z