P688
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systemsAllergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant miceInterleukin-4 deficiency promotes gallstone formationCoordinate regulation of GATA-3 and Th2 cytokine gene expression by the RNA-binding protein HuRImpaired IgA class switching in APRIL-deficient miceCross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cellsProtein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosisRUN and FYVE domain-containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4.The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to BadInvolvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cellsEssential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene lociTCR-dependent translational control of GATA-3 enhances Th2 differentiationRecombinant soluble interleukin-4 (IL-4) receptor acts as an antagonist of IL-4 in murine cutaneous LeishmaniasisLymphotactin gene expression in mast cells following Fc(epsilon) receptor I aggregation: modulation by TGF-beta, IL-4, dexamethasone, and cyclosporin AIL-4 induces IL-2 receptor p75 beta-chain gene expression and IL-2-dependent proliferation in mouse T lymphocytesIL-4 acts as a myoblast recruitment factor during mammalian muscle growthEnforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathologyInsect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFNmiR-181b negatively regulates activation-induced cytidine deaminase in B cellsDifferential requirements of CD45 for lymphocyte development and functionStat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl- and bcr/abl-induced transformation are independent of stat5STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cellsThe mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cellsStat5 activation is uniquely associated with cytokine signaling in peripheral T cellsDifferential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall componentsImpaired germinal center maturation in adenosine deaminase deficiencyIgE generation and mast cell effector function in mice deficient in IL-4 and IL-13Enhancer-mediated control of macrophage-specific arginase I expressionThe sequential activity of Gata3 and Thpok is required for the differentiation of CD1d-restricted CD4+ NKT cellsControl of inflammation, cytokine expression, and germinal center formation by BCL-6ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1)Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activityLymphotactin acts as an innate mucosal adjuvantT-bet regulates T-independent IgG2a class switchingM17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in miceIL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cellsThe transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gammaInterleukin 4 increases type 5 acid phosphatase mRNA expression in murine bone marrow macrophagesInterleukin-4 regulates lipid metabolism by inhibiting adipogenesis and promoting lipolysisSeveral different cell surface molecules control negative selection of medullary thymocytes
P921
Q24292468-59FA7957-2D8E-465C-B28E-8C11E6FAF2D3Q24293865-2916F581-D6C4-4774-BCA0-06A638553D56Q24295010-0FFF1CBA-0D7F-4FB3-B64D-1C058E2D127DQ24304394-24C54306-ED8A-4F36-AB78-FDC23FACD29BQ24313032-3A8BCB59-6D85-48C7-AD5D-C074545DB110Q24317763-EFFDC2DC-78E2-4ADA-B0B9-8A19246AAFEDQ24646492-ECAED53F-6E1D-4C53-813B-79F87DA28237Q27310220-85F037C2-2E83-4D62-8F02-30F5095A2B17Q28214523-251915C6-6637-4E48-8756-B3DC709F574EQ28244421-AD36B80D-C387-471E-BBE5-9BDA45CBACA8Q28256853-BA9A9333-6F5B-456F-9C5D-94BD1D0CDB9EQ28290084-9253FDA6-EBFF-4967-B016-4971895DC94BQ28505268-ED88D9EB-5C8E-4D13-B436-16837DCDBBFCQ28505473-FB041983-1A9B-4B7F-92D3-FF95A12617D1Q28505716-1A2E3901-E1DA-4E39-BA95-32A9CBDEF8C3Q28505736-BB7CAB05-904E-4257-A7D9-4425075D5757Q28507698-194599DB-763E-42F6-94E9-55DD10F84B44Q28508268-06224F8D-567D-4783-88BA-EC54B67531F3Q28508305-86156ABA-399A-4970-9570-A263C2643B1DQ28508466-88E272B6-8A57-4C02-97A1-5FED8025384EQ28508796-653421F6-D924-44A2-9208-D00A2722C8E7Q28510023-0F1C858B-3757-436C-9720-C0DDB75C483FQ28510411-2B004F39-AC4D-41A8-8D89-FB2A596D4867Q28511057-E3ADA62F-68B0-403F-8698-5763A25A0DC1Q28511151-2AC6AF66-0553-446C-B2E4-937DFD5E805FQ28511394-B65B44B8-B448-4481-9F72-607939EFBF1CQ28511800-4448AE51-EB23-4229-9B57-F194AD6C1050Q28585151-24D70F18-7735-47F0-BA90-2534F0E47AF0Q28585176-DAA92D34-0BDF-444F-88BF-25E4BD7ECD0BQ28585541-7DE1D325-757D-442A-882D-2746E7ECC605Q28586577-04CCEA5B-7B90-4141-B4F2-D10D644DE790Q28586849-271D4DFD-25DF-4330-8DE6-43F73BF6183FQ28588021-5231A5DD-58AF-4BCB-A34E-5D68E0B271F6Q28588710-637DEEBC-44D7-4816-B07D-323D49CB12EBQ28589356-BE52BF8C-795B-4880-9DED-912ADE497C7EQ28590243-E485A68F-F7A6-4531-9430-662AACDCD000Q28590652-0AD6331A-D994-43D6-ADB4-8F6531656E35Q28590896-C558D89B-18D9-48EA-B2AC-8349415EBF49Q28591246-7708323F-530A-4F18-93CD-C9E9B67F1451Q28591321-3551256A-C454-4424-A442-6836907E955F
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Interleukin 4
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Interleukin 4
@en
type
label
Interleukin 4
@en
altLabel
B-cell IgG differentiation factor
@en
B-cell growth factor 1
@en
B-cell stimulatory factor 1
@en
BSF-1
@en
IGG1 induction factor
@en
Il4
@en
interleukin-4
@en
lymphocyte stimulatory factor 1
@en
prefLabel
Interleukin 4
@en
P680
P681
P682
P705
P352
P637
P279
P31
P352
P637
P682
P702
P703
P705
ENSMUSP00000000889
ENSMUSP00000133617
ENSMUSP00000134414