Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice
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Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffnessThe Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cellsHypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic nicheFibulin-4 regulates expression of the tropoelastin gene and consequent elastic-fibre formation by human fibroblastsVE-statin/egfl7 regulates vascular elastogenesis by interacting with lysyl oxidasesLysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissuesMarfan syndrome: current perspectivesThe Extracellular Matrix in Bronchopulmonary Dysplasia: Target and SourceRecent Advances in the Development of Experimental Animal Models Mimicking Human Aortic AneurysmsLysyl Oxidase Activity Is Required for Ordered Collagen Fibrillogenesis by Tendon CellsMolecular Cues Guiding Matrix Stiffness in Liver FibrosisMolecular basis of neurodegeneration and neurodevelopmental defects in Menkes diseaseCharacterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber FormationThe Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibersConditional knockout of the Menkes disease copper transporter demonstrates its critical role in embryogenesisTransforming growth factor Beta2 is required for valve remodeling during heart developmentLysyl oxidase-like-2 (LOXL2) is a major isoform in chondrocytes and is critically required for differentiationLoss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in MiceLoss of lysyl oxidase-like 3 causes cleft palate and spinal deformity in miceLoss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humansInhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide.A novel chronic advanced stage abdominal aortic aneurysm murine model.The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cellsRemodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer.T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) miceMaternofetal and neonatal copper requirements revealed by enterocyte-specific deletion of the Menkes disease protein.LOXL as a target to increase the elastin content in adult skin: a dill extract induces the LOXL gene expression.Dynamic transcription programs during ES cell differentiation towards mesoderm in serum versus serum-freeBMP4 culture.Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair.Hypoxia, inflammation, and the tumor microenvironment in metastatic diseaseCaveolin 1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase.Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases.Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progressionDisruption of the aortic elastic lamina and medial calcification share genetic determinants in mice.Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose-Induced ApoptosisLysyl oxidase activity is dysregulated during impaired alveolarization of mouse and human lungs.Pseudoexfoliation syndrome-associated genetic variants affect transcription factor binding and alternative splicing of LOXL1.Prediction of marker genes associated with hypertension by bioinformatics analysesPharmacologically induced thoracic and abdominal aortic aneurysms in mice.Unraveling the mechanism of elastic fiber assembly: The roles of short fibulins
P2860
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P2860
Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice
description
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im November 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/11/05)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/11/05)
@nl
наукова стаття, опублікована в листопаді 2002
@uk
مقالة علمية (نشرت في 5-11-2002)
@ar
name
Inactivation of the lysyl oxid ...... n, and perinatal death in mice
@ast
Inactivation of the lysyl oxid ...... n, and perinatal death in mice
@en
Inactivation of the lysyl oxid ...... n, and perinatal death in mice
@nl
type
label
Inactivation of the lysyl oxid ...... n, and perinatal death in mice
@ast
Inactivation of the lysyl oxid ...... n, and perinatal death in mice
@en
Inactivation of the lysyl oxid ...... n, and perinatal death in mice
@nl
prefLabel
Inactivation of the lysyl oxid ...... n, and perinatal death in mice
@ast
Inactivation of the lysyl oxid ...... n, and perinatal death in mice
@en
Inactivation of the lysyl oxid ...... n, and perinatal death in mice
@nl
P2093
P3181
P1433
P1476
Inactivation of the lysyl oxid ...... n, and perinatal death in mice
@en
P2093
Hilkka Tikkanen
Joni M. Mäki
Juha Räsänen
Kaarin Mäkikallio
Kari I. Kivirikko
Raija Soininen
Raija Sormunen
P304
P3181
P356
10.1161/01.CIR.0000038109.84500.1E
P407
P577
2002-11-05T00:00:00Z