Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase
about
Bile acid transporters in health and diseaseDetergent screening and purification of the human liver ABC transporters BSEP (ABCB11) and MDR3 (ABCB4) expressed in the yeast Pichia pastorisBile acids alter the subcellular localization of CNT2 (concentrative nucleoside cotransporter) and increase CNT2-related transport activity in liver parenchymal cellsEnhancement of interaction of BSEP and HAX-1 on the canalicular membrane of hepatocytes in a mouse model of cholesterol cholelithiasis.Protein Kinases C-Mediated Regulations of Drug Transporter Activity, Localization and Expression.Clinical application of transcriptional activators of bile salt transporters.Cyclic AMP stimulates Mrp2 translocation by activating p38{alpha} MAPK in hepatic cells.Bile formation and secretion.The bile salt export pump: clinical and experimental aspects of genetic and acquired cholestatic liver diseaseINTRACELLULAR SIGNALING BY BILE ACIDS.ERK1/2 and p38 MAPKs are complementarily involved in estradiol 17ß-D-glucuronide-induced cholestasis: crosstalk with cPKC and PI3K.Stellate cells from rat pancreas are stem cells and can contribute to liver regenerationSandwich-cultured hepatocytes: an in vitro model to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity.Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.Activation of bile acid biosynthesis by the p38 mitogen-activated protein kinase (MAPK): hepatocyte nuclear factor-4alpha phosphorylation by the p38 MAPK is required for cholesterol 7alpha-hydroxylase expressionRegulation of neutral sphingomyelinase-2 (nSMase2) by tumor necrosis factor-alpha involves protein kinase C-delta in lung epithelial cellsDrug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis.Ursodeoxycholic acid: Mechanism of action and novel clinical applications.p38 MAPK α and β isoforms differentially regulate plasma membrane localization of MRP2.Multiple effects of acetaminophen and p38 inhibitors: towards pathway toxicology.Molecular pathogenesis of intrahepatic cholestasis of pregnancy.Bile-acid-induced cell injury and protectionWhich in vitro models could be best used to study hepatocyte polarity?Biosynthesis and trafficking of the bile salt export pump, BSEP: therapeutic implications of BSEP mutations.Dynamic localization of hepatocellular transporters in health and disease.Ursodeoxycholic acid in cholestasis: linking action mechanisms to therapeutic applications.Autoimmune BSEP disease: disease recurrence after liver transplantation for progressive familial intrahepatic cholestasis.Role of tight junctions in signal transduction: an update.Recent advances in the exploration of the bile salt export pump (BSEP/ABCB11) function.Antibody-mediated inhibition of EGFR reduces phosphate excretion and induces hyperphosphatemia and mild hypomagnesemia in mice.Anchoring of protein kinase A-regulatory subunit IIalpha to subapically positioned centrosomes mediates apical bile canalicular lumen development in response to oncostatin M but not cAMP.Exon-skipping and mRNA decay in human liver tissue: molecular consequences of pathogenic bile salt export pump mutations.A mutation within the extended X loop abolished substrate-induced ATPase activity of the human liver ATP-binding cassette (ABC) transporter MDR3The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism.Protein kinase C induces endocytosis of the sodium taurocholate cotransporting polypeptide.Hypoxia downregulates farnesoid X receptor via a hypoxia-inducible factor-independent but p38 mitogen-activated protein kinase-dependent pathway.Ursodeoxycholic acid stabilizes the bile salt export pump in the apical membrane in MDCK II cells.Expression and localization of hepatobiliary transport proteins in progressive familial intrahepatic cholestasis.Adaptive responses of renal organic anion transporter 3 (OAT3) during cholestasis.Role of mitogen-activated protein kinases in tauroursodeoxycholic acid-induced bile formation in cholestatic rat liver.
P2860
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P2860
Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase
description
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Februar 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/02/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/02/01)
@nl
наукова стаття, опублікована в лютому 2004
@uk
مقالة علمية (نشرت في فبراير 2004)
@ar
name
Trafficking of the bile salt e ...... egulated by the p38 MAP kinase
@ast
Trafficking of the bile salt e ...... egulated by the p38 MAP kinase
@en
Trafficking of the bile salt e ...... egulated by the p38 MAP kinase
@nl
type
label
Trafficking of the bile salt e ...... egulated by the p38 MAP kinase
@ast
Trafficking of the bile salt e ...... egulated by the p38 MAP kinase
@en
Trafficking of the bile salt e ...... egulated by the p38 MAP kinase
@nl
prefLabel
Trafficking of the bile salt e ...... egulated by the p38 MAP kinase
@ast
Trafficking of the bile salt e ...... egulated by the p38 MAP kinase
@en
Trafficking of the bile salt e ...... egulated by the p38 MAP kinase
@nl
P2093
P3181
P1433
P1476
Trafficking of the bile salt e ...... egulated by the p38 MAP kinase
@en
P2093
Gerrit Sütfels
Ralf Kubitz
Ralf Kölling
Thomas Kühlkamp
P304
P3181
P356
10.1053/J.GASTRO.2003.11.003
P407
P577
2004-02-01T00:00:00Z