Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis
about
Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cellsPush-and-pull regulation of the fusion pore by synaptotagmin-7Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreasSynaptotagmin-1 and -7 are functionally overlapping Ca2+ sensors for exocytosis in adrenal chromaffin cellsGenetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosisImpaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant miceSynaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic β-cellsSynaptotagmin VII regulates bone remodeling by modulating osteoclast and osteoblast secretionClass II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cellsPalmitoylation-dependent association with CD63 targets the Ca2+ sensor synaptotagmin VII to lysosomesA manual collection of Syt, Esyt, Rph3a, Rph3al, Doc2, and Dblc2 genes from 46 metazoan genomes--an open access resource for neuroscience and evolutionary biology.PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppressionSynaptotagmin-7 is an asynchronous calcium sensor for synaptic transmission in neurons expressing SNAP-23Microarray analysis of novel candidate genes responsible for glucose-stimulated insulin secretion in mouse pancreatic β cell line MIN6.Neuropeptide exocytosis involving synaptotagmin-4 and oxytocin in hypothalamic programming of body weight and energy balance.Gelsolin associates with the N terminus of syntaxin 4 to regulate insulin granule exocytosis.Novel aspects of the molecular mechanisms controlling insulin secretion.Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells.Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: mechanistic contrast between isoforms 1 and 7Neurotransmitters and Neuropeptides: New Players in the Control of Islet of Langerhans' Cell Mass and Function.Glucagon-like peptide-1 drives energy metabolism on the synaptic highway.C2-domain containing calcium sensors in neuroendocrine secretion.Local and regional control of calcium dynamics in the pancreatic islet.Differential distribution of synaptotagmin-1, -4, -7, and -9 in rat adrenal chromaffin cells.Membrane Docking of the Synaptotagmin 7 C2A Domain: Electron Paramagnetic Resonance Measurements Show Contributions from Two Membrane Binding Loops.SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans.
P2860
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P2860
Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis
description
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Januar 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/01/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/01/01)
@nl
наукова стаття, опублікована в січні 2008
@uk
مقالة علمية (نشرت عام 2008)
@ar
name
Synaptotagmin VII splice varia ...... nd regulate insulin exocytosis
@ast
Synaptotagmin VII splice varia ...... nd regulate insulin exocytosis
@en
Synaptotagmin VII splice varia ...... nd regulate insulin exocytosis
@nl
type
label
Synaptotagmin VII splice varia ...... nd regulate insulin exocytosis
@ast
Synaptotagmin VII splice varia ...... nd regulate insulin exocytosis
@en
Synaptotagmin VII splice varia ...... nd regulate insulin exocytosis
@nl
prefLabel
Synaptotagmin VII splice varia ...... nd regulate insulin exocytosis
@ast
Synaptotagmin VII splice varia ...... nd regulate insulin exocytosis
@en
Synaptotagmin VII splice varia ...... nd regulate insulin exocytosis
@nl
P2093
P356
P1433
P1476
Synaptotagmin VII splice varia ...... nd regulate insulin exocytosis
@en
P2093
Benoit R. Gauthier
Bernhard Wehrle-Haller
Claes B. Wollheim
Dominique L. Duhamel
Frédéric Saltel
Mariella Iezzi
Mitsunori Fukuda
Sten Theander
P304
P356
10.1096/FJ.07-8333COM
P407
P577
2008-01-01T00:00:00Z