The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory
about
Plant and animal pathogen recognition receptors signal through non-RD kinasesSIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanismsForward genetic analysis of Toll-like receptor responses in wild-derived mice reveals a novel antiinflammatory role for IRAK1BP1A mutation in Irak2c identifies IRAK-2 as a central component of the TLR regulatory network of wild-derived miceHelical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signallingSignal transduction by the lipopolysaccharide receptor, Toll-like receptor-4Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomesNegative regulation of toll-like receptor-mediated immune responsesIRAK-2 regulates IL-1-mediated pathogenic Th17 cell development in helminthic infection.Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analysesOsteogenic differentiation capacity of human skeletal muscle-derived progenitor cells.Limiting of the innate immune response by SF3A-dependent control of MyD88 alternative mRNA splicing.Alternatively spliced myeloid differentiation protein-2 inhibits TLR4-mediated lung inflammation.Human interleukin-1 receptor-associated kinase-2 is essential for Toll-like receptor-mediated transcriptional and post-transcriptional regulation of tumor necrosis factor alphaRegulation of toll-like receptor signaling by the SF3a mRNA splicing complex.Limiting inflammatory responses during activation of innate immunity.A comprehensive map of the toll-like receptor signaling network.The negative regulation of Toll-like receptor and associated pathways.Evidence for postinitiation regulation of mRNA biogenesis in tuberculosis.Alternative splicing in the NF-kappaB signaling pathway.The involvement of the interleukin-1 receptor-associated kinases (IRAKs) in cellular signaling networks controlling inflammationTwo phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice.Toll-like receptors as targets in chronic liver diseases.Regulation of Toll-like receptor signaling in the innate immunity.IRAK-M regulation and function in host defense and immune homeostasis.Limiting inflammation-the negative regulation of NF-κB and the NLRP3 inflammasome.Alternative Pre-mRNA Splicing of Toll-Like Receptor Signaling Components in Peripheral Blood Mononuclear Cells from ARDS Patients.A novel splice variant of interleukin-1 receptor (IL-1R)-associated kinase 1 plays a negative regulatory role in Toll/IL-1R-induced inflammatory signaling.Significance of MD-2 and MD-2B expression in rat liver during acute cholangitis.Identification and Characterization of a Splicing Variant in the 5' UTR of the Human TLR5 Gene.Breaking the tolerance for tumor: Targeting negative regulators of TLR signaling.Alternate transcription of the Toll-like receptor signaling cascade.Human Pax-5 C-terminal isoforms possess distinct transactivation properties and are differentially modulated in normal and malignant B cells.Dihydrofolate Reductase/Thymidylate Synthase Fine-Tunes the Folate Status and Controls Redox Homeostasis in Plants.Modulating inflammation through the negative regulation of NF-κB signaling.Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.Macrophages and the Recovery from Acute and Chronic Inflammation.
P2860
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P2860
The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory
description
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2004
@ast
im Juni 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/06/25)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/06/25)
@nl
наукова стаття, опублікована в червні 2004
@uk
name
The murine IRAK2 gene encodes ...... s, two of which are inhibitory
@ast
The murine IRAK2 gene encodes ...... s, two of which are inhibitory
@en
The murine IRAK2 gene encodes ...... s, two of which are inhibitory
@nl
type
label
The murine IRAK2 gene encodes ...... s, two of which are inhibitory
@ast
The murine IRAK2 gene encodes ...... s, two of which are inhibitory
@en
The murine IRAK2 gene encodes ...... s, two of which are inhibitory
@nl
prefLabel
The murine IRAK2 gene encodes ...... s, two of which are inhibitory
@ast
The murine IRAK2 gene encodes ...... s, two of which are inhibitory
@en
The murine IRAK2 gene encodes ...... s, two of which are inhibitory
@nl
P2860
P356
P1476
The murine IRAK2 gene encodes ...... s, two of which are inhibitory
@en
P2093
Matthew P Hardy
P2860
P304
27699-27708
P356
10.1074/JBC.M403068200
P407
P577
2004-04-13T00:00:00Z