Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3
about
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formationParathyroid hormone receptor type 1/Indian hedgehog expression is preserved in the growth plate of human fetuses affected with fibroblast growth factor receptor type 3 activating mutationsThe Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal developmentNestin-positive mesenchymal stem cells favour the astroglial lineage in neural progenitors and stem cells by releasing active BMP4Normal proliferation and differentiation of Hoxc-8 transgenic chondrocytes in vitroThe life cycle of chondrocytes in the developing skeleton.Fibroblast growth factor signaling in skeletal development and diseaseA pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturationRelating the chondrocyte gene network to growth plate morphology: from genes to phenotypeGenetic insights into the mechanisms of Fgf signalingRegulation of Long Bone Growth in Vertebrates; It Is Time to Catch UpSixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasiasSynovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spineBMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formationDefective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasiaDisruption of fibroblast growth factor receptor 3 signaling results in defects in cellular differentiation, neuronal patterning, and hearing impairmentMultiple congenital malformations of Wolf-Hirschhorn syndrome are recapitulated in Fgfrl1 null miceGain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesisCoordination of chondrogenesis and osteogenesis by fibroblast growth factor 18Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritisFGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesisDwarfism and early death in mice lacking C-type natriuretic peptideRetinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouseFGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopodFGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescenceESCRT-II/Vps25 constrains digit number by endosome-mediated selective modulation of FGF-SHH signaling.Conditional expression of Wnt4 during chondrogenesis leads to dwarfism in miceIdentification of SOX9 interaction sites in the genome of chondrocytesMultiple osteochondromas: clinicopathological and genetic spectrum and suggestions for clinical management.Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesisUncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3FGFR3 induces degradation of BMP type I receptor to regulate skeletal development.Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth platePhenotype profile of a genetic mouse model for Muenke syndrome.A novel FGFR3-binding peptide inhibits FGFR3 signaling and reverses the lethal phenotype of mice mimicking human thanatophoric dysplasia.The Fibroblast Growth Factor signaling pathwayMolecular, phenotypic aspects and therapeutic horizons of rare genetic bone disorders.Conditional ablation of Pten in osteoprogenitors stimulates FGF signalingA genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3.Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway
P2860
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P2860
Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3
description
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Dezember 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/12/01)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/12/01)
@nl
наукова стаття, опублікована в грудні 1998
@uk
مقالة علمية (نشرت في ديسمبر 1998)
@ar
name
Repression of hedgehog signali ...... blast growth factor receptor 3
@ast
Repression of hedgehog signali ...... blast growth factor receptor 3
@en
Repression of hedgehog signali ...... blast growth factor receptor 3
@nl
type
label
Repression of hedgehog signali ...... blast growth factor receptor 3
@ast
Repression of hedgehog signali ...... blast growth factor receptor 3
@en
Repression of hedgehog signali ...... blast growth factor receptor 3
@nl
prefLabel
Repression of hedgehog signali ...... blast growth factor receptor 3
@ast
Repression of hedgehog signali ...... blast growth factor receptor 3
@en
Repression of hedgehog signali ...... blast growth factor receptor 3
@nl
P2093
P3181
P1433
P1476
Repression of hedgehog signali ...... blast growth factor receptor 3
@en
P2093
D. M. Ornitz
J. D. Coffin
J. S. Colvin
M. C. Naski
P304
P3181
P407
P577
1998-12-01T00:00:00Z