Multiple congenital malformations of Wolf-Hirschhorn syndrome are recapitulated in Fgfrl1 null mice
about
Cytogenomic Aberrations in Congenital Cardiovascular MalformationsOf mice and men: molecular genetics of congenital heart diseaseHectd1 is required for development of the junctional zone of the placentaGiraffe genome sequence reveals clues to its unique morphology and physiology.Extending the family table: Insights from beyond vertebrates into the regulation of embryonic development by FGFsDeletions involving genes WHSC1 and LETM1 may be necessary, but are not sufficient to cause Wolf-Hirschhorn Syndrome.Prenatal ultrasound findings observed in the Wolf-Hirschhorn syndrome: data from the registry of congenital malformations in Auvergne.FGFRL1 is a neglected putative actor of the FGF signalling pathway present in all major metazoan phylaComparison of the receptor FGFRL1 from sea urchins and humans illustrates evolution of a zinc binding motif in the intracellular domain.The FGFRL1 receptor is shed from cell membranes, binds fibroblast growth factors (FGFs), and antagonizes FGF signaling in Xenopus embryosGenome-wide association studies identified multiple genetic loci for body size at four growth stages in Chinese Holstein cattleExamination of FGFRL1 as a candidate gene for diaphragmatic defects at chromosome 4p16.3 shows that Fgfrl1 null mice have reduced expression of Tpm3, sarcomere genes and Lrtm1 in the diaphragm.Targeted disruption of the intracellular domain of receptor FgfrL1 in mice.Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signalingRapid fusion and syncytium formation of heterologous cells upon expression of the FGFRL1 receptor.The Fibroblast Growth Factor signaling pathwayWolf-Hirschhorn syndrome: A review and update.Fine-grained facial phenotype-genotype analysis in Wolf-Hirschhorn syndrome.Prenatal diagnosis of Wolf-Hirschhorn syndrome confirmed by comparative genomic hybridization array: report of two cases and review of the literatureIdentification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies.Genome-wide comparison of FGFRL1 with structurally related surface receptors.Receptor FGFRL1 does not promote cell proliferation but induces cell adhesionEvidence that the novel receptor FGFRL1 signals indirectly via FGFR1.Biology of FGFRL1, the fifth fibroblast growth factor receptor.Role of FGFRL1 and other FGF signaling proteins in early kidney development.Congenital diaphragmatic hernias: from genes to mechanisms to therapies.Interstitial 287 kb deletion of 4p16.3 including FGFRL1 gene associated with language impairment and overgrowth.Cytogenomic Integrative Network Analysis of the Critical Region Associated with Wolf-Hirschhorn Syndrome.
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P2860
Multiple congenital malformations of Wolf-Hirschhorn syndrome are recapitulated in Fgfrl1 null mice
description
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
scientific journal article
@en
vedecký článok (publikovaný 2009/05/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/05/01)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в травні 2009
@uk
مقالة علمية (نشرت في مايو 2009)
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name
Multiple congenital malformati ...... apitulated in Fgfrl1 null mice
@ast
Multiple congenital malformati ...... apitulated in Fgfrl1 null mice
@en
Multiple congenital malformati ...... apitulated in Fgfrl1 null mice
@nl
type
label
Multiple congenital malformati ...... apitulated in Fgfrl1 null mice
@ast
Multiple congenital malformati ...... apitulated in Fgfrl1 null mice
@en
Multiple congenital malformati ...... apitulated in Fgfrl1 null mice
@nl
prefLabel
Multiple congenital malformati ...... apitulated in Fgfrl1 null mice
@ast
Multiple congenital malformati ...... apitulated in Fgfrl1 null mice
@en
Multiple congenital malformati ...... apitulated in Fgfrl1 null mice
@nl
P2093
P2860
P50
P3181
P356
P1476
Multiple congenital malformati ...... apitulated in Fgfrl1 null mice
@en
P2093
Catarina Catela
Esfir Slonimsky
Pascal Te Welscher
P2860
P304
P3181
P356
10.1242/DMM.002287
P577
2009-04-21T00:00:00Z