The transforming growth factor beta receptors types I, II, and III form hetero-oligomeric complexes in the presence of ligand
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Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptorTGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairsBone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptorsBetaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sitesRecombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agentDifferent domains regulate homomeric and heteromeric complex formation among type I and type II transforming growth factor-beta receptors.Characterization of novel transforming growth factor-beta type I receptors found in malignant pleural effusion tumor cells.The roles of TGFβ in the tumour microenvironment.The regulation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumor promotion by estradiol in female A/J miceAssociated changes of lipid peroxidation and transforming growth factor beta1 levels in human colon cancer during tumour progression.Beta3 integrin and Src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells.Mapping of the ligand binding domain of the transforming growth factor beta receptor type III by deletion mutagenesis.Proliferation of mutators in A cell population.Signaling by chimeric erythropoietin-TGF-beta receptors: homodimerization of the cytoplasmic domain of the type I TGF-beta receptor and heterodimerization with the type II receptor are both required for intracellular signal transduction.Loss of functional cell surface transforming growth factor beta (TGF-beta) type 1 receptor correlates with insensitivity to TGF-beta in chronic lymphocytic leukemia.The types II and III transforming growth factor-beta receptors form homo-oligomers.TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors.Endoglin modulates cellular responses to TGF-beta 1.Oligomeric structure of type I and type II transforming growth factor beta receptors: homodimers form in the ER and persist at the plasma membrane.Independent changes in type I and type II receptors for transforming growth factor beta induced by bone morphogenetic protein 2 parallel expression of the osteoblast phenotype.Transforming Growth Factor-beta2 protects the small intestine during methotrexate treatment in rats possibly by reducing stem cell cyclingTGFbeta induces SIK to negatively regulate type I receptor kinase signaling.Complexity in interpretation of embryonic epithelial-mesenchymal transition in response to transforming growth factor-beta signalingMonocrotaline pyrrole induces Smad nuclear accumulation and altered signaling expression in human pulmonary arterial endothelial cellsReconstitution and transphosphorylation of TGF-beta receptor complexes.GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex.Paracrine co-delivery of TGF-β and IL-2 using CD4-targeted nanoparticles for induction and maintenance of regulatory T cells.Signaling Receptors for TGF-β Family Members.Expression and autoregulation of transforming growth factor beta receptor mRNA in small-cell lung cancer cell lines.A dominant inhibitory mutant of the type II transforming growth factor beta receptor in the malignant progression of a cutaneous T-cell lymphomaRestoration of TGF-beta signalling reduces tumorigenicity in human lung cancer cells.Mechanism of TGFbeta receptor inhibition by FKBP12Colon cancer cells that are not growth inhibited by TGF-beta lack functional type I and type II TGF-beta receptors.Plasmin cleaves betaglycan and releases a 60 kDa transforming growth factor-beta complex from the cell surface.Lipid Peroxidation and Transforming Growth Factor-β1 Levels in Gastric Cancer at Pathologic StagesThe type III TGF-β receptor betaglycan transmembrane-cytoplasmic domain fragment is stable after ectodomain cleavage and is a substrate of the intramembrane protease γ-secretase.Regulation of fibroblast procollagen production. Transforming growth factor-beta 1 induces prostaglandin E2 but not procollagen synthesis via a pertussis toxin-sensitive G-proteinBetaglycan has multiple binding sites for transforming growth factor-beta 1.Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling.TGF-beta receptor signaling activates SMADs
P2860
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P2860
The transforming growth factor beta receptors types I, II, and III form hetero-oligomeric complexes in the presence of ligand
description
1993 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1993
@ast
im Oktober 1993 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1993/10/25)
@sk
vědecký článek publikovaný v roce 1993
@cs
wetenschappelijk artikel (gepubliceerd op 1993/10/25)
@nl
наукова стаття, опублікована в жовтні 1993
@uk
name
The transforming growth factor ...... exes in the presence of ligand
@ast
The transforming growth factor ...... exes in the presence of ligand
@en
The transforming growth factor ...... exes in the presence of ligand
@nl
type
label
The transforming growth factor ...... exes in the presence of ligand
@ast
The transforming growth factor ...... exes in the presence of ligand
@en
The transforming growth factor ...... exes in the presence of ligand
@nl
prefLabel
The transforming growth factor ...... exes in the presence of ligand
@ast
The transforming growth factor ...... exes in the presence of ligand
@en
The transforming growth factor ...... exes in the presence of ligand
@nl
P2093
P1476
The transforming growth factor ...... exes in the presence of ligand
@en
P2093
A. Moustakas
J. Plamondon
M. D. O'Connor-McCourt
Y. I. Henis
P304
22215–22218
P407
P577
1993-10-25T00:00:00Z