Recombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agent

Recombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agent

Item
http://www.wikidata.org/entity/Q28360679
Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF-  bindingTbetaR-II discriminates the high- and low-affinity TGF-beta isoforms via two hydrogen-bonded ion pairsRoles for the type III TGF-beta receptor in human cancerThe balance of cell surface and soluble type III TGF-β receptor regulates BMP signaling in normal and cancerous mammary epithelial cells.Type III TGF-β receptor enhances colon cancer cell migration and anchorage-independent growth.Activation of the transforming growth factor-β/SMAD transcriptional pathway underlies a novel tumor-promoting role of sulfatase 1 in hepatocellular carcinoma.Implications of TGFβ on Transcriptome and Cellular Biofunctions of Palatal MesenchymeTGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma.Expression, purification and characterization of BG(E)RII: a novel pan-TGFbeta inhibitorMacrophage-specific deletion of transforming growth factor-β1 does not prevent renal fibrosis after severe ischemia-reperfusion or obstructive injury.Betaglycan has two independent domains required for high affinity TGF-beta binding: proteolytic cleavage separates the domains and inactivates the neutralizing activity of the soluble receptor.Expression of TGFβ3 and its effects on migratory and invasive behavior of prostate cancer cells: involvement of PI3-kinase/AKT signaling pathway.Absence of Thy-1 results in TGF-β induced MMP-9 expression and confers a profibrotic phenotype to human lung fibroblasts.The type III TGF-β receptor betaglycan transmembrane-cytoplasmic domain fragment is stable after ectodomain cleavage and is a substrate of the intramembrane protease γ-secretase.Transforming Growth Factor Beta Signaling in Cutaneous Wound Healing: Lessons Learned from Animal Studies.Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling.
P2860

Recombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agent

Item
http://www.wikidata.org/entity/Q28360679
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Recombinant soluble betaglycan ...... factor-beta neutralizing agent
@ast
Recombinant soluble betaglycan ...... factor-beta neutralizing agent
@en
Recombinant soluble betaglycan ...... factor-beta neutralizing agent
@nl
type
label
Recombinant soluble betaglycan ...... factor-beta neutralizing agent
@ast
Recombinant soluble betaglycan ...... factor-beta neutralizing agent
@en
Recombinant soluble betaglycan ...... factor-beta neutralizing agent
@nl
prefLabel
Recombinant soluble betaglycan ...... factor-beta neutralizing agent
@ast
Recombinant soluble betaglycan ...... factor-beta neutralizing agent
@en
Recombinant soluble betaglycan ...... factor-beta neutralizing agent
@nl
P1433
P1476
P2093
P2860
P304
P31
P407
P433
P478
P577
P698
P932
P1433
P1476
Recombinant soluble betaglycan ...... factor-beta neutralizing agent
@en
P2093
P2860
P304
P31
P407
P433
P478
P577
P698
P932