Synergistic binding of sterol regulatory element-binding protein and NF-Y to the farnesyl diphosphate synthase promoter is critical for sterol-regulated expression of the gene
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Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein responseOccupancy and function of the -150 sterol regulatory element and -65 E-box in nutritional regulation of the fatty acid synthase gene in living animalsNFY interacts with the promoter region of two genes involved in the rat peroxisomal fatty acid beta-oxidation: the multifunctional protein type 1 and the 3-ketoacyl-CoA B thiolaseCo-stimulation of promoter for low density lipoprotein receptor gene by sterol regulatory element-binding protein and Sp1 is specifically disrupted by the yin yang 1 proteinTranscriptional regulation of the murine acetyl-CoA synthetase 1 gene through multiple clustered binding sites for sterol regulatory element-binding proteins and a single neighboring site for Sp1Differential transcriptional regulation of the human squalene synthase gene by sterol regulatory element-binding proteins (SREBP) 1a and 2 and involvement of 5' DNA sequence elements in the regulationCBP is required for sterol-regulated and sterol regulatory element-binding protein-regulated transcriptionDirect interaction between USF and SREBP-1c mediates synergistic activation of the fatty-acid synthase promoterYY1 is a negative regulator of transcription of three sterol regulatory element-binding protein-responsive genesIdentification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteinsGlucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes.A novel sequence element is involved in the transcriptional regulation of expression of the ERG1 (squalene epoxidase) gene in Saccharomyces cerevisiae.High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding.Tandem ChoRE and CCAAT motifs and associated factors regulate Txnip expression in response to glucose or adenosine-containing moleculesDifferential gene regulation of StarD4 and StarD5 cholesterol transfer proteins. Activation of StarD4 by sterol regulatory element-binding protein-2 and StarD5 by endoplasmic reticulum stress.Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2.Sterol regulation of human fatty acid synthase promoter I requires nuclear factor-Y- and Sp-1-binding sites.Specificity in cholesterol regulation of gene expression by coevolution of sterol regulatory DNA element and its binding protein.ATF6 modulates SREBP2-mediated lipogenesis.Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cellsBlunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N).Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's beenDifferent sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase.Gene-specific transcriptional activity of the insulin cAMP-responsive element is conferred by NF-Y in combination with cAMP response element-binding protein.The roles of sterol regulatory element-binding proteins in the transactivation of the rat ATP citrate-lyase promoter.Pleiotropic effects of a schweinfurthin on isoprenoid homeostasisCoactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors.A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.Differential regulation of human and mouse orphan nuclear receptor small heterodimer partner promoter by sterol regulatory element binding protein-1.The FIRE3-mediated sterol response of the FAS promoter requires NF-Y/CBF as a coactivator.Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene.FIRE3 in the promoter of the rat fatty acid synthase (FAS) gene binds the ubiquitous transcription factors CBF and USF but does not mediate an insulin response in a rat hepatoma cell line.A critical role for cAMP response element-binding protein (CREB) as a Co-activator in sterol-regulated transcription of 3-hydroxy-3-methylglutaryl coenzyme A synthase promoter.Polyunsaturated fatty acid suppression of fatty acid synthase (FASN): evidence for dietary modulation of NF-Y binding to the Fasn promoter by SREBP-1c.Identification of diazepam-binding Inhibitor/Acyl-CoA-binding protein as a sterol regulatory element-binding protein-responsive gene.Molecular cloning, characterization, and differential expression of a farnesyl-diphosphate synthase gene from the basidiomycetous fungus Ganoderma lucidum.Cholesterol biosynthesis from lanosterol. A concerted role for Sp1 and NF-Y-binding sites for sterol-mediated regulation of rat 7-dehydrocholesterol reductase gene expression.Sterol regulatory element-binding protein-1 interacts with the nuclear thyroid hormone receptor to enhance acetyl-CoA carboxylase-alpha transcription in hepatocytes.A role for cyclic AMP response element-binding protein (CREB) but not the highly similar ATF-2 protein in sterol regulation of the promoter for 3-hydroxy-3-methylglutaryl coenzyme A reductase.
P2860
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P2860
Synergistic binding of sterol regulatory element-binding protein and NF-Y to the farnesyl diphosphate synthase promoter is critical for sterol-regulated expression of the gene
description
1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1996
@ast
im Oktober 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/10/04)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/10/04)
@nl
наукова стаття, опублікована в жовтні 1996
@uk
name
Synergistic binding of sterol ...... gulated expression of the gene
@ast
Synergistic binding of sterol ...... gulated expression of the gene
@en
Synergistic binding of sterol ...... gulated expression of the gene
@nl
type
label
Synergistic binding of sterol ...... gulated expression of the gene
@ast
Synergistic binding of sterol ...... gulated expression of the gene
@en
Synergistic binding of sterol ...... gulated expression of the gene
@nl
prefLabel
Synergistic binding of sterol ...... gulated expression of the gene
@ast
Synergistic binding of sterol ...... gulated expression of the gene
@en
Synergistic binding of sterol ...... gulated expression of the gene
@nl
P2860
P356
P1476
Synergistic binding of sterol ...... gulated expression of the gene
@en
P2093
P A Edwards
S M Jackson
P2860
P304
24359-24364
P356
10.1074/JBC.271.40.24359
P407
P577
1996-10-01T00:00:00Z