Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2.
about
Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating proteinCREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P.Luman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysisA proteolytic pathway that controls the cholesterol content of membranes, cells, and bloodMammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localizationDiverse roles of SIRT1 in cancer biology and lipid metabolismCleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavageReconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and InsigsThe luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the GolgiA role for smooth endoplasmic reticulum membrane cholesterol ester in determining the intracellular location and regulation of sterol-regulatory-element-binding protein-2Decreased lipid synthesis in livers of mice with disrupted Site-1 protease geneMaintaining cholesterol homeostasis: sterol regulatory element-binding proteinsCleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studiesBiosynthesis and enzymatic characterization of human SKI-1/S1P and the processing of its inhibitory prosegmentAra12 subtilisin-like protease from Arabidopsis thaliana: purification, substrate specificity and tissue localization.Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells.Regulated intramembrane proteolysis of FtsL protein and the control of cell division in Bacillus subtilis.Perilipin-mediated lipid droplet formation in adipocytes promotes sterol regulatory element-binding protein-1 processing and triacylglyceride accumulation.The Streptomyces coelicolor developmental transcription factor sigmaBldN is synthesized as a proproteinAdipose tissue insulin resistance in adolescents with and without type 2 diabetes.Lack of suppression of circulating free fatty acids and hypercholesterolemia during weight loss on a high-fat, low-carbohydrate diet.Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi.A genetic screen for the isolation and characterization of site-specific proteases.Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.An orchestrated program regulating secretory pathway genes and cargos by the transmembrane transcription factor CREB-H.Nelfinavir and nelfinavir analogs block site-2 protease cleavage to inhibit castration-resistant prostate cancer.Cholesterol: from feeding to gene regulation.Structural requirements for sterol regulatory element-binding protein (SREBP) cleavage in fission yeastBlunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N).Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's beenRegulation of Sterol Biosynthesis in the Human Fungal Pathogen Aspergillus fumigatus: Opportunities for Therapeutic DevelopmentSterol regulatory element-binding protein (SREBP) cleavage regulates Golgi-to-endoplasmic reticulum recycling of SREBP cleavage-activating protein (SCAP).New insights into S2P signaling cascades: regulation, variation, and conservation.Regulation of cholesterol and fatty acid synthesis.Regulation of cholesterol homeostasis.A pathway approach to investigate the function and regulation of SREBPs.Biosynthesis and cellular trafficking of the convertase SKI-1/S1P: ectodomain shedding requires SKI-1 activity.Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress.Development of protein-based inhibitors of the proprotein of convertase SKI-1/S1P: processing of SREBP-2, ATF6, and a viral glycoprotein.Allyl isothiocyanate suppresses the proteolytic activation of sterol regulatory element-binding proteins and de novo fatty acid and cholesterol synthesis.
P2860
Q24320818-E9D17214-A369-4D4D-8E67-D2925C0DBB30Q24338672-466249CA-FCD3-494C-BD56-6D8AE16956AFQ24537679-3378B11D-E9FD-4C67-93F5-4F7E85C1CCBDQ24614744-7484D5DA-E600-46A4-90F1-4EDD8E7A18ACQ24675925-A7F50445-2F4F-452F-9A9A-E26A934A5660Q26997827-9D5E5A47-9E39-42A6-99F2-A9B33A830F1DQ27657164-D18A250D-375B-4E8C-9D5E-BC99186724CAQ28184828-5A37C4F5-515D-4640-B0A6-BC2E63211B76Q28217040-7F42E2AD-DCEE-4F95-B0DF-74BCE025BD3EQ28346400-8D1A487D-53D7-4934-A7C5-9ABC9DEBEA76Q28588943-0C36864B-D8D1-4100-8A48-A5765B3D6952Q28609710-F70B45AA-C018-4CAE-9509-1C71B17CEB0AQ28611460-28A40E9A-D2D6-4FB2-9B33-6436C31A3AF9Q28640526-D498FDBC-AEA9-4D29-8205-B22B750EB2B0Q30754193-37F8C4D6-DB55-4991-9092-C89A0CE07D87Q31582971-2B3C52BF-56EB-4ABB-A117-5B63427EE1C2Q33259339-A444FF9D-46DF-43DB-9797-FAACBAA5CA7AQ34755570-A70A6497-0D1B-43DD-913F-64AA79D8F08CQ34810663-09166FC8-A683-4CAD-A270-0A9179C21F49Q34845017-63DB11E2-4451-424D-9F58-2DEFE725FAAFQ35093065-ABD28EF7-CC62-445D-926B-C3D390A3FEF3Q35644888-E7E881A3-0F03-4DCC-B2B5-E4235606EFD6Q35972875-D8C8F139-C6A1-4EEA-8478-83EF03B3A966Q36619009-679C7FA1-9235-49CF-8BF5-9E5C3A5E0108Q36673609-3A59A5BF-0FEF-48F8-AF49-116DB10D5E20Q36752045-7D067960-B615-41D6-BB03-515A13D57094Q36776696-6DF4305F-3E8F-47A6-BC97-33C6E99F08CAQ37012432-118AF26D-D4A4-4DAF-966A-A9F65193D47AQ37388151-2648FD01-65A3-4FB4-A93C-32FBF4AE8323Q37426801-97110A73-085D-4775-BC37-FA1028DAE03BQ37617395-5079A07A-EA61-4627-BFF8-555B2A514476Q37635793-31158D69-68A9-4127-AF54-26BA6BC3651AQ37788073-0DB30A36-6A88-47F3-92E4-93E7D8D1ED92Q37866898-B42C7C3F-32DE-4444-9F0D-3FB22CDCB479Q37947137-25857C2D-2EB7-4560-A43D-3355701EAAD9Q38091672-24E746B3-2C5F-4911-BD26-74E869BA0026Q38293570-A9067B36-1A5D-46AF-BFAC-00E0E99DE46BQ38316703-993120CF-0E92-4698-97F3-AF2A5E800B53Q38344667-2F410906-4353-4677-A906-C88DAB8EEA2CQ38798594-3D1C8D81-5A8F-4DB0-9F78-D77EB2A32F15
P2860
Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2.
description
1997 nî lūn-bûn
@nan
1997 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Cleavage site for sterol-regul ...... ory element-binding protein-2.
@ast
Cleavage site for sterol-regul ...... ory element-binding protein-2.
@en
Cleavage site for sterol-regul ...... ory element-binding protein-2.
@nl
type
label
Cleavage site for sterol-regul ...... ory element-binding protein-2.
@ast
Cleavage site for sterol-regul ...... ory element-binding protein-2.
@en
Cleavage site for sterol-regul ...... ory element-binding protein-2.
@nl
prefLabel
Cleavage site for sterol-regul ...... ory element-binding protein-2.
@ast
Cleavage site for sterol-regul ...... ory element-binding protein-2.
@en
Cleavage site for sterol-regul ...... ory element-binding protein-2.
@nl
P2093
P2860
P356
P1476
Cleavage site for sterol-regul ...... ory element-binding protein-2.
@en
P2093
E A Duncan
J L Goldstein
P2860
P304
12778-12785
P356
10.1074/JBC.272.19.12778
P407
P577
1997-05-01T00:00:00Z